A method for purifying a polyethylene glycol compound represented by formula [1], including a Step (A) of dissolving the compound represented by formula [1] in an organic solvent having a Hildebrand solubility parameter of 8 to 10 (cal/cm.sup.3).sup.1/2 to obtain a solution, and a Step (B) of mixing the solution with 0.1 to 1 part by mass of an adsorbent made from a hydrotalcite having a specific surface area of 50 to 200 m.sup.2/g with respect to 1 part by mass of the compound of the formula [1] to prepare a slurry,

##STR00001##

where Z, Y.sup.1, Y.sup.2, A, Polymer, X, a, b, l and m are as defined herein.

A method for purifying a polyethylene glycol compound represented by formula [1], including a Step (A) of dissolving the compound represented by formula [1] in an organic solvent having a Hildebrand solubility parameter of 8 to 10 (cal/cm.sup.3).sup.1/2 to obtain a solution, and a Step (B) of mixing the solution with 0.1 to 1 part by mass of an adsorbent made from a hydrotalcite having a specific surface area of 50 to 200 m.sup.2/g with respect to 1 part by mass of the compound of the formula [1] to prepare a slurry,

##STR00001##

where Z, Y.sup.1, Y.sup.2, A, Polymer, X, a, b, l and m are as defined herein.

The present disclosure relates to a method of immobilizing a phenolic compound having a M.sub.w≥500 g/mol, wherein the method comprises the steps of ionizing the phenolic compound by subjecting it to a base; and contacting, under agitation, the ionized phenolic compound with a cross-linked resin comprising the functionality of —C(═0)—CHXCH.sub.2R, wherein X is chosen from the group consisting of Br, Cl, I, CN, OMs, OTs, or OTf, and R is H, CH.sub.3 or an branched or unbranched alkyl having 1 to 8 carbon atoms, in the presence of a base and a solvent. The present disclosure also relates to a method of removing phenolic compounds having a M.sub.w≥500 g/mol from a composition comprising compounds having at least one alkoxy silane group. The present disclosure also relates to the use of a method according to the present disclosure as well as to a product, from which at least one phenolic compound having a M.sub.w>500 g/mol has been removed by a method according to the present disclosure.

The present disclosure relates to a method of immobilizing a phenolic compound having a M.sub.w≥500 g/mol, wherein the method comprises the steps of ionizing the phenolic compound by subjecting it to a base; and contacting, under agitation, the ionized phenolic compound with a cross-linked resin comprising the functionality of —C(═0)—CHXCH.sub.2R, wherein X is chosen from the group consisting of Br, Cl, I, CN, OMs, OTs, or OTf, and R is H, CH.sub.3 or an branched or unbranched alkyl having 1 to 8 carbon atoms, in the presence of a base and a solvent. The present disclosure also relates to a method of removing phenolic compounds having a M.sub.w≥500 g/mol from a composition comprising compounds having at least one alkoxy silane group. The present disclosure also relates to the use of a method according to the present disclosure as well as to a product, from which at least one phenolic compound having a M.sub.w>500 g/mol has been removed by a method according to the present disclosure.

The disclosure provides a preparation process of an allyl alcohol polyether with a low potassium and sodium content, comprising the following steps: reacting allyl alcohol with a mixture of epoxypropane and oxacyclopropane to prepare an allyl alcohol oligomer crude product with a molecular weight of 150-1500; reducing the total content of potassium and sodium ions in the allyl alcohol oligomer crude product prepared in step S1 to 2 ppm or less through a cation exchange resin; and reacting the allyl alcohol oligomer product treated in step S2 with the mixture of epoxypropane and oxacyclopropane to prepare allyl alcohol high-molecular-weight polyether with a molecular weight of 2000-5000. According to the present disclosure, the total content of potassium and sodium ions in the product is reduced to 2 ppm or less, and the product has a good double bond protection rate.

The disclosure provides a preparation process of an allyl alcohol polyether with a low potassium and sodium content, comprising the following steps: reacting allyl alcohol with a mixture of epoxypropane and oxacyclopropane to prepare an allyl alcohol oligomer crude product with a molecular weight of 150-1500; reducing the total content of potassium and sodium ions in the allyl alcohol oligomer crude product prepared in step S1 to 2 ppm or less through a cation exchange resin; and reacting the allyl alcohol oligomer product treated in step S2 with the mixture of epoxypropane and oxacyclopropane to prepare allyl alcohol high-molecular-weight polyether with a molecular weight of 2000-5000. According to the present disclosure, the total content of potassium and sodium ions in the product is reduced to 2 ppm or less, and the product has a good double bond protection rate.

A method for purifying a branched polyethylene glycol, which includes adding, to a branched polyethylene glycol compound represented by the following formula [1] and having a weight average molecular weight of 40000 or more:

##STR00001##

where Z, Y.sup.1, Y.sup.2, A, Polymer, l, m and b are as defined herein, at least one solid acid selected from magnesium silicate, aluminum silicate, and aluminum magnesium silicate and having a specific surface area of 50 to 250 m.sup.2/g in the presence of an aprotic organic solvent to obtain a mixture; stirring the mixture; and subsequently separating the solid acid.

A method for purifying a branched polyethylene glycol, which includes adding, to a branched polyethylene glycol compound represented by the following formula [1] and having a weight average molecular weight of 40000 or more:

##STR00001##

where Z, Y.sup.1, Y.sup.2, A, Polymer, l, m and b are as defined herein, at least one solid acid selected from magnesium silicate, aluminum silicate, and aluminum magnesium silicate and having a specific surface area of 50 to 250 m.sup.2/g in the presence of an aprotic organic solvent to obtain a mixture; stirring the mixture; and subsequently separating the solid acid.

Methods for preparing a PEG composition by co-precipitation of two or more components to produce a substantially homogenous powder. According to some embodiments, the two or more components are at least and partially soluble in a solvent, and at least one component is a functionalized PEG. Contacting the at least two component with the solvent at least partially dissolves the components which are then co-precipitated. The resulting product is substantially homogenous, unlike product made by other methods. The PEG composition may be co-precipitated with additional compounds, such as a colorant like indocyanine green.

Methods for preparing a PEG composition by co-precipitation of two or more components to produce a substantially homogenous powder. According to some embodiments, the two or more components are at least and partially soluble in a solvent, and at least one component is a functionalized PEG. Contacting the at least two component with the solvent at least partially dissolves the components which are then co-precipitated. The resulting product is substantially homogenous, unlike product made by other methods. The PEG composition may be co-precipitated with additional compounds, such as a colorant like indocyanine green.