The invention relates to a linear polyglycerol compound, comprising a backbone of linearly linked glycerol residues. This compound is characterized in that it carries a plurality of substituents in the nature of covalently bound sulfates, wherein a degree of substitution of the backbone is preferably between 30 and 100%. A method of manufacturing the compound as well as uses of this compound and similar compounds are also disclosed.

According to one aspect of the present invention, an organic fluorine compound is represented by a general formula
(R-π-E-CH.sub.2-A-CH.sub.2-E′).sub.n-π′-G  (1B) (where n is an integer of 2 to 5, A is a divalent perfluoropolyether group, π is an arylene group or a single bond, R is an alkenyl group or an alkynyl group, and E and E′ are each independently an ether bond or an ester bond or a group that is represented by a chemical formula
—O—CH.sub.2CH(OH)CH.sub.2O—
π′ is a group in which n+1 hydrogen atoms are separated from benzene, G is an organic group containing a fullerene skeleton, the n number of groups each of which is represented by a general formula
R-π-E-CH.sub.2-A-CH.sub.2-E′-
may be the same or different, and at least one π among the n number of π is an arylene group).

According to one aspect of the present invention, an organic fluorine compound is represented by a general formula
(R-π-E-CH.sub.2-A-CH.sub.2-E′).sub.n-π′-G  (1B) (where n is an integer of 2 to 5, A is a divalent perfluoropolyether group, π is an arylene group or a single bond, R is an alkenyl group or an alkynyl group, and E and E′ are each independently an ether bond or an ester bond or a group that is represented by a chemical formula
—O—CH.sub.2CH(OH)CH.sub.2O—
π′ is a group in which n+1 hydrogen atoms are separated from benzene, G is an organic group containing a fullerene skeleton, the n number of groups each of which is represented by a general formula
R-π-E-CH.sub.2-A-CH.sub.2-E′-
may be the same or different, and at least one π among the n number of π is an arylene group).

High temperature lubricants for magnetic media are provided. One such lubricant includes fluoroalkyl, fluoroalkenyl, perfluoroalkyl, or perfluoroalkyl ether segments, anchoring functional groups engageable with a protective overcoat of a magnetic recording media, and cyclic functional groups. The lubricants can be used in conjunction with a magnetic recording medium and/or a magnetic data storage system.

The present invention provides a production method for obtaining, by a simple method, a polyalkylene oxide whose molecular weight and polydispersity are controlled in the desired range.

The method for producing a polyalkylene oxide of the present disclosure comprises step 1 of performing a polymerization reaction of an alkylene oxide in the presence of a chain transfer agent to obtain a high-molecular-weight polyalkylene oxide; and step 2 of irradiating the high-molecular-weight polyalkylene oxide obtained in step 1 with radiation to obtain a polyalkylene oxide; wherein the amount of the chain transfer agent is 800 mass ppm or more relative to the alkylene oxide, and the high-molecular-weight polyalkylene oxide has a viscosity in a 1 mass % aqueous solution of 6000 mPas or less.

The present disclosure is directed to a plasticizer composition, polymeric compositions containing the plasticizer composition, and coated conductors comprising the polymeric composition. The plasticizer composition comprises an epoxidized fatty acid alkyl ester having an APHA color value of less than 100, a triepoxide content of at least 6.5 weight percent, and an oxirane oxygen content of at least 5 grams oxirane per 100 grams of epoxidized fatty acid alkyl ester.

High temperature lubricants for magnetic media are provided. One such lubricant includes fluoroalkyl, fluoroalkenyl, perfluoroalkyl, or perfluoroalkyl ether segments, anchoring functional groups engageable with a protective overcoat of a magnetic recording media, and cyclic functional groups. The lubricants can be used in conjunction with a magnetic recording medium and/or a magnetic data storage system.

The present invention discloses a method of preparing PEGylated biomolecules having controllable binding sites, including the following steps: (1) binding a blocker to a biomolecule; (2) PEGylating the biomolecule; and (3) separating the blocker from the biomolecule. In another aspect, the present invention discloses a method for preparing PEGylated IL-2 having controllable binding sites, including the following steps: (1) binding IL-2 to an IL-2α receptor, closing the a binding site of the IL-2; (2) PEGylating, coupling PEG with the IL-2; and (3) separating the IL-2 from the IL-2α receptor. By regulating IL-2 binding sites and a PEGylation process only adding one or two polyethylene glycols, the IL-2 is caused to selectively bind to an IL-2R βγ-type receptor.

The present invention discloses a method of preparing PEGylated biomolecules having controllable binding sites, including the following steps: (1) binding a blocker to a biomolecule; (2) PEGylating the biomolecule; and (3) separating the blocker from the biomolecule. In another aspect, the present invention discloses a method for preparing PEGylated IL-2 having controllable binding sites, including the following steps: (1) binding IL-2 to an IL-2α receptor, closing the a binding site of the IL-2; (2) PEGylating, coupling PEG with the IL-2; and (3) separating the IL-2 from the IL-2α receptor. By regulating IL-2 binding sites and a PEGylation process only adding one or two polyethylene glycols, the IL-2 is caused to selectively bind to an IL-2R βγ-type receptor.

A preformed thermoplastic polymer is dispersed into a polyol via a mechanical dispersion process. A stabilizer is present to stabilize the dispersed polymer particles. An antisolvent is also present. The antisolvent has been found to lead to smaller particle size and increased dispersion stability.