Patent classifications
C09B1/005
NIR to SWIR fluorescent compounds for imaging and detection
This disclosure provides a family of compounds that absorb and fluoresce in the short wave infrared region (SWIR, optionally 1000 nm to 1300 nm), including hydrophilic compounds that exhibit absorption and emission spectral profiles in aqueous solutions substantially similar to those observed in organic solvents such as methanol or DMSO. The compounds can be chemically linked to biomolecules including proteins, nucleic acids, and therapeutic small molecules. The compounds are useful for imaging in a variety of medical, biological and diagnostic applications, including SWIR in vivo imaging of regions of interest within a mammal.
NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION
This disclosure provides a family of compounds that absorb and fluoresce in the short wave infrared region (SWIR, optionally 1000 nm to 1300 nm), including hydrophilic compounds that exhibit absorption and emission spectral profiles in aqueous solutions substantially similar to those observed in organic solvents such as methanol or DMSO. The compounds can be chemically linked to biomolecules including proteins, nucleic acids, and therapeutic small molecules. The compounds are useful for imaging in a variety of medical, biological and diagnostic applications, including SWIR in vivo imaging of regions of interest within a mammal.
Electrowetting element
Electrowetting element including a compound comprising a plurality of colorant moieties and a linker. The plurality of colorant moieties includes a first colorant moiety having a first net dipole and a second colorant moiety having a second net dipole. The plurality of colorant moieties are linked by and disposed around the linker so that the first net dipole and the second net dipole at least partially cancel each other.
NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION
This disclosure provides a family of compounds that absorb and fluoresce in the short wave infrared region (SWIR, optionally 1000 nm to 1300 nm), including hydrophilic compounds that exhibit absorption and emission spectral profiles in aqueous solutions substantially similar to those observed in organic solvents such as methanol or DMSO. The compounds can be chemically linked to biomolecules including proteins, nucleic acids, and therapeutic small molecules. The compounds are useful for imaging in a variety of medical, biological and diagnostic applications, including SWIR in vivo imaging of regions of interest within a mammal.
DISPLAY DEVICE
A display device includes: a light unit for emitting blue light; a color conversion panel on the light unit; a display panel between the light unit and the color conversion panel, the display panel comprising transistors; and column spacers between the transistors and the color conversion panel, the column spacers overlapping the transistors. The color conversion panel includes: a substrate; color conversion layers between the substrate and the display panel, the color conversion layers comprising semiconductor nanocrystals; a transmission layer between the substrate and the display panel; and polarization layers between the color conversion layers and the display panel and between the transmission layer and the display panel. The column spacers include a pigment that absorbs blue light.
METHOD FOR VISUALIZATION OF CALCIUM CONTAINING COMPONENTS IN BIOLOGICAL SYSTEMS
Provided are compositions and methods for visualizing the skeletal tissues of a biological specimen, comprising treating the specimen with a calcium chelating agent, a staining solution, and a clearing solution.
ELECTROWETTING ELEMENT
Electrowetting element including a compound comprising a plurality of colorant moieties and a linker. The plurality of colorant moieties includes a first colorant moiety having a first net dipole and a second colorant moiety having a second net dipole. The plurality of colorant moieties are linked by and disposed around the linker so that the first net dipole and the second net dipole at least partially cancel each other.