The present disclosure provides a laundry care composition having at least one laundry care ingredient and at least one leuco composition conforming to Formula (I):
Ar.sup.1Ar.sup.2Ar.sup.3CH  (I)
wherein Ar.sup.2 and Ar.sup.3 are independently a carbocyclic aryl or heteroaryl, and Ar.sup.1 is selected from the group consisting of: unsubstituted phenyl, electron deficient carbocyclic aryl, and heteroaryl. The present disclosure also provides a method of determining an authentic laundry care composition and test kits for detecting authentic laundry care compositions.

The present disclosure provides a laundry care composition having at least one laundry care ingredient and at least one leuco composition conforming to Formula (I):
Ar.sup.1Ar.sup.2Ar.sup.3CH  (I)
wherein Ar.sup.2 and Ar.sup.3 are independently a carbocyclic aryl or heteroaryl, and Ar.sup.1 is selected from the group consisting of: unsubstituted phenyl, electron deficient carbocyclic aryl, and heteroaryl. The present disclosure also provides a method of determining an authentic laundry care composition and test kits for detecting authentic laundry care compositions.

Molecular probes for detecting and imaging pancreatic cancer are disclosed. The probes are modified benzoxanthene fluorophores, which are selectively taken up by pancreatic cancer cells, such as pancreatic ductal adenocarcinoma cells. Embodiments of the disclosed probes are useful for pancreatic cancer detection, therapeutic monitoring, and/or image-guided surgery.

The present disclosure provides a laundry care composition having at least one laundry care ingredient and at least one leuco composition conforming to Formula (I):

##STR00001##

wherein Ar.sup.2 and Ar.sup.3 are independently a carbocyclic aryl or heteroaryl, and Ar.sup.1 is selected from the group consisting of: unsubstituted phenyl, electron deficient carbocyclic aryl, and heteroaryl. The present disclosure also provides a method of determining an authentic laundry care composition and test kits for detecting authentic laundry care compositions.

The present disclosure provides a laundry care composition having at least one laundry care ingredient and at least one leuco composition conforming to Formula (I):

##STR00001##

wherein Ar.sup.2 and Ar.sup.3 are independently a carbocyclic aryl or heteroaryl, and Ar.sup.1 is selected from the group consisting of: unsubstituted phenyl, electron deficient carbocyclic aryl, and heteroaryl. The present disclosure also provides a method of determining an authentic laundry care composition and test kits for detecting authentic laundry care compositions.

[Problems] To provided are a reversibly thermochromic composition that shows black during color development by using a fluoran derivative having a specific structure as an electron-donating color-developing organic compound, turns colorless during decoloration, and is excellent in light resistance and a microcapsule pigment encapsulating the reversibly thermochromic composition.

[Solution] Disclosed is a reversibly thermochromic composition including: (a) a fluoran derivative having a specific structure as an electron-donating color-developing organic compound; (b) a compound having a specific structure as an electron-accepting compound; and (c) a reaction medium which reversibly induces an electron transfer reaction between the component (a) and the component (b) in a specific temperature range, and a reversibly thermochromic microcapsule pigment encapsulating the reversibly thermochromic composition.

[Problems] To provided are a reversibly thermochromic composition that shows black during color development by using a fluoran derivative having a specific structure as an electron-donating color-developing organic compound, turns colorless during decoloration, and is excellent in light resistance and a microcapsule pigment encapsulating the reversibly thermochromic composition.

[Solution] Disclosed is a reversibly thermochromic composition including: (a) a fluoran derivative having a specific structure as an electron-donating color-developing organic compound; (b) a compound having a specific structure as an electron-accepting compound; and (c) a reaction medium which reversibly induces an electron transfer reaction between the component (a) and the component (b) in a specific temperature range, and a reversibly thermochromic microcapsule pigment encapsulating the reversibly thermochromic composition.

A method of making a triarylmethane leuco compound comprises reacting an aromatic aldehyde compound, a first oxyalkylenated aryl compound, and a second oxyalkylenated aryl compound in a condensation reaction in the presence of an acidic catalyst to produce the triarylmethane leuco compound. The first oxyalkylenated aryl compound is oxyalkylenated with ethylene oxide. The second oxyalkylenated aryl compound is oxyalkylenated with propylene oxide or with both ethylene oxide and propylene oxide.

A method of making a triarylmethane leuco compound comprises reacting an aromatic aldehyde compound, a first oxyalkylenated aryl compound, and a second oxyalkylenated aryl compound in a condensation reaction in the presence of an acidic catalyst to produce the triarylmethane leuco compound. The first oxyalkylenated aryl compound is oxyalkylenated with ethylene oxide. The second oxyalkylenated aryl compound is oxyalkylenated with propylene oxide or with both ethylene oxide and propylene oxide.

Molecular probes for detecting and imaging pancreatic cancer are disclosed. The probes are modified benzoxanthene fluorophores, which are selectively taken up by pancreatic cancer cells, such as pancreatic ductal adenocarcinoma cells. Embodiments of the disclosed probes are useful for pancreatic cancer detection, therapeutic monitoring, and/or image-guided surgery.