The present disclosure provides new attenuated Pepino mosaic viruses useful in the control of plant disease. Compositions for biological control of plant disease are also provided as well as methods for producing Pepino mosaic virus resistant plants.

Methods for treatment and prevention of Potexvirus disease in plants are provided. Further provided are compositions for treatment or prevention of Potexvirus disease in plants, and methods for reducing expression of a Potexvirus gene and for identifying polynucleotides useful in modulating gene expression in plant viruses.

The present disclosure provides new attenuated Pepino mosaic viruses useful in the control of plant disease. Compositions for biological control of plant disease are also provided as well as methods for producing Pepino mosaic virus resistant plants.