Provided is a fermentation fungal substance of Astragalus membranaceus/Paecilomyces cicadae and its use. The fermentation fungal substance is obtained by solid fermentation with Astragalus membranaceus powder as a fermentation substrate and Paecilomyces cicadae as a fermentation strain. The fermentation fungal substance of Astragalus membranaceus/Paecilomyces cicadae in the present disclosure plays a significant role in treating hyperuricemia and/or hypertriglyceridemia.

The invention relates to the method for producing the fungus Paecilomyces spp., and to the uses, methods and nematicide compositions for the prevention and/or control and/or eradication of nematodes that form cysts developing in solanaceae cultures. Said invention includes a system for the application of the fungus combined with the rotation of cultures for effectively and efficiently reducing the viability of the cysts of nematodes in solanaceae cultures.

Provided herein are methods of preventing/controlling phytoparasitic nematodes in migratory and sedentary endoparasites belonging to families Anguinidae, Aphelenchidae, Aphelenchoididae, Criconematidae, Dolichodoridae, Hemicycliophoridae, Heteroderidae, Hoplolaimidae, Iotonchidae, Neotylenchidae, Pratylenchidae, Sphaerulariidae, Tilenchidae, and Tylenchulidae: Suborder Tylenchina; Longidoridae: Suborder Dorylaimina; Trichodoridae: Suborder Diphtherophorina using Paecilomyces carneus. The compositions and processes disclosed herein are useful in the prevention and/or control and/or eradication of phytoparasitic nematodes that infect and/or infest the vast majority of cultures for animal and human consumption, while optimum conditions are created in the soil for improving crop yield, with the option of getting organic products.

The present invention relates to a paecilomyces variotii var. brunneolus GPP1101B (microorganism deposit number KCTC 119938BP) isolated during a ginseng fermentation process, and a preparation using the same. According to the present invention, remarkable anticancer, immune regulation, mutation inhibition and antibacterial effects are obtained by injecting the strain or the preparation into a ginseng extract or into a red ginseng extract.

A method of producing a fungal biomass includes culturing genetically changed genomes of filamentous fungus on a medium, which has non-metabolizable glucose analogue and a growth carbon source comprising glycerol, isolating improved fungal strains from the cultured genetically changed genomes, wherein the improved fungal strains exhibit growth on the medium, pre-cultivating the isolated improved fungal strains, fermenting the pre-cultivated improved fungal strains with a feedstock to obtain a fermentation broth, wherein the feedstock has a fermentation carbon source with glycerol, collecting the fermentation broth, and separating the fungal biomass from the fermentation broth.