A miniature cooling system includes a base metal sheet, a flow channel layer, a piezoelectrically actuated metal sheet, a piezoelectric boundary compression layer and two piezoelectric ceramic vibrators. The flow channel layer is located on the base metal sheet and includes a first chamber, a second chamber, an inlet channel, a linking channel and an outlet channel. The inlet channel links the outside environment to the first chamber. The linking channel links the first chamber and the second chamber. The outlet channel links the second chamber to the outside environment. The piezoelectrically actuated metal sheet is located on the flow channel layer. The piezoelectric boundary compression layer is located on the piezoelectrically actuated metal sheet. The piezoelectric boundary compression layer includes two containing areas, and the two containing areas are respectively located above the first chamber and the second chamber.

A liquid handling device includes a chamber including a first opening and a second opening in a wall surface; a first channel connected to the first opening of the chamber; and a second channel connected to the second opening of the chamber. The chamber includes a recess and a film disposed to cover an opening of the recess, the film including an air chamber part curved to a side opposite to the recess. In plan view, an entirety of the air chamber part is disposed inside the opening of the recess.

A mini air pump which includes a diaphragm, a bladder base provided with penetrating bladder holes and air inlet channels, a pump body having a valve seat and a pump cover, an air inlet valve, an air outlet valve, a relief valve and a preload member is revealed. The valve seat is stacked over the diaphragm. An exhaust chamber and a spring chamber are constructed by the valve seat and the pump cover. The valve seat has exhaust channels communicating with the bladder cavity. A communicating return channel is constructed by the diaphragm, the bladder base and the valve seat. The return channel is communicating with the air inlet channel but not communicating with the spring chamber. A spring of the preload member applies a preload to the relief valve. Thereby the relief valve acts more accurately and the mini air pump is more stable in use.

Linear peristaltic pumps for use with fluidic cartridges. An apparatus includes a reagent cartridge configured to be received within a cartridge receptacle of a system. The reagent cartridge includes a reagent reservoir and a body including a surface that forms depressions. Each depression has a fluid inlet and a fluid outlet and is fluidly coupled to at least one other depression. The reagent cartridge also includes a deformable material coupled to the surface of the body and includes portions. Each portion covers one of the depressions to define chambers. The portions of the deformable material are movable relative to the depressions between a first position outside of a dimensional envelope of the body and a second position within the dimensional envelope of the body.

Certain aspects of the present disclosure provide a surgical cassette configured to engage a first plurality of rollers of a first roller head. The cassette comprises a face coupled to a first substrate, the face being at a first angle with respect to the first roller head's axis of rotation and a wall of first substrate being at a second angle with respect to the axis of rotation, wherein the first angle is different from the second angle. The cassette also comprises a first sheet positioned on the wall's surface, wherein the first sheet and the wall form first one or more pump segments configured to engage the first plurality of rollers in a position where force applied by each one of the first plurality of rollers on the first one or more pump segments has a direction that is not parallel to the first roller head's axis of rotation.

An analysis device, a cartridge and a method for analysing a sample are provided, including a rotatable pump head having contact elements that are resiliently biased in the axial direction acting on an elastically deformable pump chamber in order to pump or convey a fluid, such as the sample, a reagent or a gas, when the pump head rotates, in particular in a defined and/or efficient manner.

Linear peristaltic pumps for use with fluidic cartridges. An apparatus includes a reagent cartridge configured to be received within a cartridge receptacle of a system. The reagent cartridge includes a reagent reservoir and a body including a surface that forms depressions. Each depression has a fluid inlet and a fluid outlet and is fluidly coupled to at least one other depression. The reagent cartridge also includes a deformable material coupled to the surface of the body and includes portions. Each portion covers one of the depressions to define chambers. The portions of the deformable material are movable relative to the depressions between a first position outside of a dimensional envelope of the body and a second position within the dimensional envelope of the body.

Certain aspects of the present disclosure provide a surgical cassette configured to engage a first plurality of rollers of a first roller head. The cassette comprises a face coupled to a first substrate, the face being at a first angle with respect to the first roller head's axis of rotation and a wall of first substrate being at a second angle with respect to the axis of rotation, wherein the first angle is different from the second angle. The cassette also comprises a first sheet positioned on the wall's surface, wherein the first sheet and the wall form first one or more pump segments configured to engage the first plurality of rollers in a position where force applied by each one of the first plurality of rollers on the first one or more pump segments has a direction that is not parallel to the first roller head's axis of rotation.

A miniature cooling system includes a base metal sheet, a flow channel layer, a piezoelectrically actuated metal sheet, a piezoelectric boundary compression layer and two piezoelectric ceramic vibrators. The flow channel layer is located on the base metal sheet and includes a first chamber, a second chamber, an inlet channel, a linking channel and an outlet channel. The inlet channel links the outside environment to the first chamber. The linking channel links the first chamber and the second chamber. The outlet channel links the second chamber to the outside environment. The piezoelectrically actuated metal sheet is located on the flow channel layer. The piezoelectric boundary compression layer is located on the piezoelectrically actuated metal sheet. The piezoelectric boundary compression layer includes two containing areas, and the two containing areas are respectively located above the first chamber and the second chamber.

A membrane system comprising a membrane and connecting elements for connecting the membrane to a membrane pump for conveying a fluid, which membrane pump has a drive shaft designed for an oscillating translatory movement perpendicular to the plane of the membrane during operation of the membrane pump and has an external thread at an end portion for engagement with the membrane system by screwing. To ensure a secure and torque-proof connection between the membrane and the connecting element to be screwed to a drive shaft, the connecting elements comprise a threaded socket, a thrust ring and a thrust plate.