An apparatus and method for providing a simpler and more robust mechanism for transporting materials to be dried through a vacuum microwave chamber in rotating containers. The apparatus (20) has a vacuum chamber (22), an input end (26) to introduce a container (24) into the chamber, and a discharge end (28) to remove the container. The container has spur gear teeth (60) extending along its outer circumferential surface. The apparatus has a single roller (42) having spur gear teeth (46) extending along its outer circumferential surface. The spur gear teeth of the roller mesh with the spur gear teeth of the container such that rotation of the roller about its longitudinal axis rotates the container. The apparatus also includes means for holding the container on the roller, means for moving the container through the chamber, a microwave generator 76 arranged for transmission of microwave radiation from the generator into the chamber, and means for reducing pressure inside the chamber.

A carrier plate for inserting containers filled with a medical, pharmaceutical or cosmetic substance into a freeze dryer, wherein the carrier plate comprises a plurality of receptacles that are configured to each receive a container. Furthermore, the present application relates to a carrier plate arrangement having a plurality of such carrier plates. Furthermore, the present application relates to a loading system for a freeze dryer, wherein the loading system comprises one or more handling devices and one or more such carrier plates or the carrier plate arrangement. Furthermore, the present application relates to a loading system and to a freeze-drying system having such a loading system.

Provided is a gas fill fixture for use in lyophilization, a related system and method. The gas fill fixture includes a chassis, fill indicator and a lid, such that the chassis and lid together form a cavity for receiving a flexible lyophilization container. The system includes a lyophilization container, a lyophilizer and a gas fill fixture incorporating a chassis, a fill indicator and a lid. The method includes process steps for using the system to lyophilize a fluid.

A process for freeze drying a material. The process has the steps of (a) placing material to be freeze-dried in a vessel, the vessel comprising a container having a base, and at least one wall defining an opening at one end; (b) applying a membrane to the at least one wall to thereby cover the opening, wherein the membrane comprises an aperture which, in use, is aligned with the opening; and (c) subjecting the vessel to a lyophilisation procedure, wherein the membrane is in place on the container during the lyophilisation procedure.

A method of preparing a pharmaceutical product in a single multiple chamber flexible bag. A pharmaceutical product is introduced in a liquid state into a first chamber of the flexible bag through a first port. The pharmaceutical product is lyophilized within the first chamber of the flexible bag to provide a lyophilized pharmaceutical product. The flexible bag has a second chamber and the first chamber and the second chamber are separated by a breakable seal. The second chamber further includes a reconstituting solution for reconstituting the lyophilized pharmaceutical product in the first chamber. A user may apply pressure to the flexible bag to break the seal and mix the lyophilized pharmaceutical product and the reconstituting solution to order to administer the pharmaceutical product to a patient.

An object of the present invention is to provide a new freeze-dried article that is easy to handle and a producing method thereof. A freeze-dried structure of the present invention includes a freeze-dried article and a support member, wherein the support member has an embedded region and a protruding region, the embedded region of the support member is embedded in the internal portion of the freeze-dried article, and the protruding region of the support member protrudes outward from the freeze-dried article.

Provided is a loading tray assembly for housing a lyophilization container and a related system and method. The loading tray assembly includes a chassis including a contact void configured to facilitate direct contact between the attached lyophilization container and a lyophilizer shelf. The method includes securing a multi-part lyophilization container including a peelable seal on a lyophilization loading tray assembly, inputting a liquid into a non-breathable section of the lyophilization container, loading the tray assembly into a lyophilizer, freezing the liquid, applying heat energy and a vacuum, the vacuum causing an opening of the peelable seal and occluding the lyophilization container to isolate the frozen liquid.

A drying rack having a stainless steel rectangular tubed frame with two vertical frame members and at least three horizontal frame members. The horizontal frame members have a plurality of rails extending from the horizontal members. The each rail of the plurality of rails is each equally spaced and extends from opposites sides of each horizontal member. The rails are configured to hold cannabis plant matter after harvest. The rails may be angled slightly for helping to retain the cannabis plant matter on the rails during use. The drying rack is on casters for mobility and rotation.

Provided is a multi-part lyophilization container for lyophilizing a fluid, storing the lyophilizate, reconstituting the lyophilizate, and infusing the reconstituted lyophilizate into a patient, including a method of using same. The container includes a front surface, a back surface, a non-breathable section including a port region, a breathable section including a breathable membrane, and an occlusion zone encompassing a boundary between the non-breathable section and the breathable section. The non-breathable section is configured to accommodate any of a liquid, a solid, a gas or combination thereof. The breathable section is configured to accommodate only a gas. The method includes creating a temporary seal between the non-breathable section of the container and the breathable section, inputting a liquid into the non-breathable section, freezing the liquid, removing the temporary seal to allow vapor transport between the non-breathable section and the breathable section, and adding heat energy the frozen liquid under vacuum.

A method of preparing a pharmaceutical product in a single multiple chamber flexible bag. A pharmaceutical product is introduced in a liquid state into a first chamber of the flexible bag through a first port. The pharmaceutical product is lyophilized within the first chamber of the flexible bag to provide a lyophilized pharmaceutical product. The flexible bag has a second chamber and the first chamber and the second chamber are separated by a breakable seal. The second chamber further includes a reconstituting solution for reconstituting the lyophilized pharmaceutical product in the first chamber. A user may apply pressure to the flexible bag to break the seal and mix the lyophilized pharmaceutical product and the reconstituting solution to order to administer the pharmaceutical product to a patient.