Multichannel optical coherence systems and methods involving optical coherence tomography (OCT) subsystems are operably and respectively connected to optical fibers of a multichannel optical probe, such that each optical fiber forms at least a distal portion of a sample beam path of a respective OCT subsystem. The optical fibers are in optical communication with distal optical elements such that external beam paths associated therewith are directed towards a common spatial region external to the housing. Image processing computer hardware is employed to process OCT signals obtained from the plurality of OCT subsystems to generate an OCT image dataset comprising a plurality of OCT A-scans and process the OCT image dataset to generate volumetric image data based on known positions and orientations of the external beam paths associated with the OCT subsystems.

Exemplary systems, devices, methods, apparatus and computer-accessible media for providing and/or utilizing optical frequency domain imaging (OFDI) and fluorescence of structures and, e.g., multimodality imaging using OFDI techniques and fluorescence imaging techniques are described. For example, an arrangement can provide at least one electro-magnetic radiation to an anatomical structure. Such exemplary arrangement can include at least one optical core and at least one cladding at least partially surrounding the fiber(s). A region between the optical core(s) and the cladding(s) can have an index that is different from indexes of the optical core(s) and the cladding(s). The arrangement can also include at least one apparatus which is configured to transmit the radiation(s) via the optical core(s) and the cladding(s) to the anatomical structure.

The invention relates to an assembly comprising a interferometer for carrying out an optical coherence tomography, wherein the interferometer is divided into two spatially spaced-apart interferometer parts (1, 2), wherein the two interferometer parts (1, 2) can be moved related to one another and are optically connected to one another via flexible light guides (3, 4, 5), which bridge the spatial distance, wherein according to the invention, an assembly having an interferometer is provided, which is as unsusceptible as possible to the effects brought about by bending a tube cable packet and allows for an optimum signal-to-noise ratio or an optimum image quality of an OCT image, characterised in that at least one first flexible light guide (3) is designed as a polarisation-maintaining light guide consisting of two connected polarisation-maintaining light-guiding fibres (3a, 3b).

The present disclosure provides a common-path optical waveguide probe. The common-path optical waveguide probe includes an optical waveguide, a lens, and a reference reflector. The optical waveguide includes a proximal end and a distal end. The lens is coupled to the distal end. The reference reflector is positioned between the optical waveguide and the lens. The disclosure also provides a catheter and an optical coherence tomography system utilizing the common-path optical waveguide probe. The disclosure also provides methods of making and using the common-path optical waveguide probe.

A fiber-optic point probe for a distance measurement system has an optical fiber that can be connected to a light source or an evaluation device. Illumination light is transmitted via the optical fiber to a beam-forming element and is converted into beam-formed illumination light. The beam-formed illumination light is guided along a first optical axis to a planar surface of a deflection element and is reflected thereby. The beam-formed illumination light reflected on the planar surface spreads along a second optical axis, exits on a spherical end surface of the deflection element and forms a focused illumination beam having a focus area outside of the deflection element. An object surface arranged in the focus area can be probed such that a distance relative to a probe internal reference surface can be determined in a contactless manner.

One or more devices, systems, methods and storage mediums for performing common path optical coherence tomography (OCT) with a controlled reference signal and efficient geometric coupling are provided. Examples of such applications include imaging, evaluating and diagnosing biological objects, such as, but not limited to, for Gastro-intestinal, cardio and/or ophthalmic applications, and being obtained via one or more optical instruments, such as, but not limited to, optical probes (e.g., common path probes), common path catheters, common path capsules and common path needles (e.g., a biopsy needle). Preferably, the OCT devices, systems methods and storage mediums include or involve a reference reflection or a reference plane that is at least one of: (i) disposed in the collimation field or path; and (ii) is perpendicular (or normal) or substantially perpendicular (or substantially normal) to light propagation. One or more embodiments may include beam shaping optics to properly image luminal or other hollow structures or objects.

An optical device provided with an optical parts position adjusting and fixing device for adjusting and fixing the position of the optical parts moving in an optical axis direction, wherein the position adjusting and fixing device is provided with a long slotted hole extended in the optical axis direction formed on a side surface of the optical parts; a fixing means which is mounted on an object to be fixed of the optical parts and which is movable along the long slotted hole; a non-penetrating screw hole formed in the fixing means and which is divided by a slit; and a screw which is screwed into the screw hole and spreads the slit when screwed into the screw hole so as to press the outer surface of the fixing means against the inner surface of the long slotted hole.

An ophthalmic intraoperative imaging system may include a handheld light probe including a first optical fiber and a second optical fiber. The system may include an illumination light source configured to transmit an illumination beam for intraocular illumination via the first optical fiber of the light probe. The system may include an optical coherence tomography (OCT) light source configured to transmit an OCT beam towards an intraocular region of interest (ROI) via the second optical fiber of the light probe. The system may include an OCT detector configured to detect light reflected by the intraocular ROI. The system may include a processor configured to control the illumination light source and the OCT light source, obtain an OCT signal, obtain a B-mode OCT image of the intraocular ROI by freehand sweeping of the handheld light probe across the intraocular ROI, and control a display to display the B-mode OCT image.

A system for optical coherence tomography includes a source of optical radiation, an optical fiber, and a graded index fiber attached to a distal end of the optical fiber. The optical fiber and the graded index fiber are together configured to provide a common path for optical radiation reflected from a reference interface at a distal end of the graded index fiber and from a target.

An optical measuring probe for measuring inner and/or outer diameters of objects, uses a first optical element for focusing or collimating an optical beam onto a surface of an object. A second optical element for splitting the optical beam into a first measuring beam and a second measuring beam is provided in the optical measuring probe in such a way that the second measuring beam is guided out of the measuring probe in a direction opposite the direction of the first measuring beam and that the first measuring beam forms a first scan point and the second measuring beam forms a second scan point. Also described is a corresponding method for measuring diameters using the optical measuring probe. The optical measuring probe and the associated method make it possible to optically measure inner and outer diameters of measuring probes objects in a simple manner.