A squeeze doser with a childproof cap is described herein. The squeeze doser with a childproof cap includes a container, a reservoir, and a cap. The container includes a neck. A reservoir is coupled with the neck of the container, wherein the reservoir further comprises a spout and at least one notch located on an outer surface of the neck, said spout coupled with a fill tube that guides liquid stored in the container to the spout, the spout including one or more holes positioned to maintain a predetermined dosage of liquid within the reservoir. The cap is releaseably attached to the neck and includes at least one protrusion that is configured to mate with the at least one notch of the neck, whereby the at least one protrusion coupled with the at least one notch renders the container childproof.

The present invention provides for a method for the treatment of a respiratory disease, disorder or condition, or a viral infection or viral disease, disorder or condition in a subject, the method comprising the step of administering to said subject a medically active liquid in nebulized form by inhalation, wherein the medically active liquid comprises niclosamide or a pharmaceutically acceptable salt thereof and wherein the medically active liquid is administered in nebulized form using an inhalation device.

The present invention provides for a method for the treatment of a respiratory disease, disorder or condition, or a viral infection or viral disease, disorder or condition in a subject, the method comprising the step of administering to the subject a medically active liquid in nebulized form by inhalation, wherein the medically active liquid comprises niclosamide or a pharmaceutically acceptable salt thereof and wherein the medically active liquid is administered in nebulized form using an inhalation device, and wherein the inhalation device used to administer the medically active liquid comprising the niclosamide or a pharmaceutically acceptable salt thereof is a soft-mist-inhaler.

A squeeze doser with a childproof cap is described herein. The squeeze doser with a childproof cap includes a container, a reservoir, and a cap. The container includes a neck. A reservoir is coupled with the neck of the container, wherein the reservoir further comprises a spout and at least one notch located on an outer surface of the neck, said spout coupled with a fill tube that guides liquid stored in the container to the spout, the spout including one or more holes positioned to maintain a predetermined dosage of liquid within the reservoir. The cap is releaseably attached to the neck and includes at least one protrusion that is configured to mate with the at least one notch of the neck, whereby the at least one protrusion coupled with the at least one notch renders the container childproof.

A liquid dosing device for a container includes a dosing chamber having a front end and a back end. An outlet passage is located at the front end. A plunger is located in the dosing chamber, divides it in a front and a back space, and is moveable between a forward position in which the plunger closes off the outlet passage, and a backward position, in which the front space has a maximal volume. An inlet passage provides fluid communication between the front space and the container. A timer passage provides fluid communication between the container and the back space. A release passage, being greater than the timer passage, provides fluid communication between the back space and the container. A valve assembly at the release passage includes a valve seat located at the back end of the dosing chamber.

A liquid dosing device for dispensing a metered dose of liquid from a squeezable container, comprising an outlet passage leading to a discharge opening; a dosing chamber positioned behind said discharge opening and having at least one entrance opening allowing a charging flow of liquid from said container into said dosing chamber under the influence of weight of liquid, and a drive opening allowing a control flow of liquid from said container into said dosing chamber in response on a rise of pressure of liquid in the squeezable container; a floating plunger movably arranged in the dosing chamber so as to advance upon said rise of pressure from a rest position in which under the influence of a lifting force of buoyancy said floating plunger closes said drive opening, into a blocking position in which said floating plunger blocks said outlet passage, wherein said floating plunger when advancing into said blocking position, pushes said liquid charged into said dosing chamber, to said outlet passage; a stop seat upon which said floating plunger acts in its blocking position, and a sealing lip for closing said outlet passage, being arranged such that a seat-sided portion of the floating plunger or a plunger-sided portion of the stop seat and said sealing lip is formed, particularly injection-mold, of one single piece of the same plastic material.

A dosing bottle has a container; a riser; a cap piece; a standpipe connected to the riser and one or more return openings in a tubular wall of the standpipe; and a closure member. The closure member is rotatably attached to the cap piece and defines an interior dosing volume and a dispenser opening. The closure member is axially movable relative to the cap piece between a closed position and an open position. The open position allows a liquid in the interior volume of the container to flow through the riser and through the return opening and into the interior dosing volume.

A two-piece measured-dose dispensing closure (10) includes a cup-shaped measuring chamber (12) and a rotatable dispensing control lid (14). In use, the dispensing control lid is axially moved relative to the measuring chamber by rotation between a first closed position, a second intermediate dispensing position, and a third drain position.

A squeeze doser with a childproof cap is described herein. The squeeze doser with a childproof cap includes a container, a reservoir, and a cap. The container includes a neck. A reservoir is coupled with the neck of the container, wherein the reservoir further comprises a spout and at least one notch located on an outer surface of the neck, said spout coupled with a fill tube that guides liquid stored in the container to the spout, the spout including one or more holes positioned to maintain a predetermined dosage of liquid within the reservoir. The cap is releaseably attached to the neck and includes at least one protrusion that is configured to mate with the at least one notch of the neck, whereby the at least one protrusion coupled with the at least one notch renders the container childproof.

A two-piece measured-dose dispensing closure (10) includes a cup-shaped measuring chamber (12) and a rotatable dispensing control lid (14). In use, the dispensing control lid is axially moved relative to the measuring chamber by rotation between a first closed position, a second intermediate dispensing position, and a third drain position.