Apparatus and methods for measuring infrared absorption of a sample that includes delivering a pulse of infrared radiation to a region of the sample, delivering pulses of radiation of a shorter wavelength than infrared radiation to a sub-region within the region, and using one or more properties of the induced photoacoustic signals to create a signal indicative of infrared absorption of the sub-region of the sample.

The invention is a device and method for detecting an analyte in a medium. An exciting light source produces an exciting light wave, which propagates to the medium and heats the latter. The device comprises a transducer for detecting the heating of the medium. According to one embodiment, the transducer is a thermal transducer, configured to detect a variation in the temperature of the medium. According to another embodiment, the transducer is an acoustic transducer, configured to detect a photoacoustic wave propagating from the medium. Whatever the embodiment, the transducer employs a membrane, on which a waveguide is placed. The waveguide comprises a resonant optical cavity. Transduction is achieved by analyzing a variation in a resonant wavelength of the optical cavity.

Methods, devices, apparatus, and systems for three-dimensional (3D) contoured scanning photoacoustic imaging and/or deep learning virtual staining.

The disclosure includes a system for photoacoustic inspection of an object. The system includes a broadband emission source configured to generate an emission beam, a direction apparatus including at least one spectrum splitter configured to split the emission beam into at least a first and a second component, the direction apparatus being configured to sequentially direct the respective components to N respective locations on the object at N times to generate N respective acoustic waves within the object. The N respective locations and N times are such that the respective N acoustic waves at least semi-constructively interfere to generate a respective propagating acoustic wave within the object. The system also includes a vibration sensing system configured to detect said respective propagating acoustic waves at a respective detection location on the object.

The present invention discloses a method for detecting a microstructure of a functionally graded material based on digital acousto-optic holography, including the following steps: excite a sample with an ultrasonic wave; record a light wave; form a single tomographic acousto-optic hologram; perform numerical reconstruction of phase information, and perform global detection. The present invention uses an acoustic-optic modulation device to modulate a laser light source of a laser of a laser device to form two light waves of different frequencies. The two light waves each constitute a Mach-Zehnder interference system to record reflection wave information and transmission wave information of an ultrasound, and are finally combined and recorded in the same hologram to form the single tomographic acousto-optic hologram. A reflection-transmission dual-mode interference optical path is beneficial to avoiding the mutual interference of the reflection wave information and the transmission wave information, and being able to improve the integrity of information record and information redundancy by using time delay integration with point sensing and surface output to scan CCD through an image collector and cooperate with a synchronous control system to perform surface scanning and record for information of an ultrasound carrier.

Methods and apparatuses for manufacturing are disclosed, including (a) providing an apparatus having: a laser; scanner; powder injection system; powder spreading system; dichroic filter; imager-and-processor; and computer; (b) programming the computer with specifications of a sample; (c) using the computer to set initial parameters based on the sample specifications; (d) adjusting a stage to position the sample; (e) focusing and scanning electromagnetic radiation onto the sample while powder is concurrently injected onto the sample in order to deposit a layer; (f) capturing two-dimensional images of the sample and probing the sample to determine whether the deposited layer was manufactured per the specifications; (g) use the computer to adjust the three-dimensional manufacturing parameters based on the determination made in step (f) prior to additively manufacturing a subsequent layer or making repairs; and (h) repeating steps (d), (e), (f), and (g) until the manufacture is complete. Other embodiments are described and claimed.

A non-destructive opto-acoustic metrology device detects the presence and location of non-uniformities in a film stack that includes a large number, e.g., 50 or more, transparent layers. A transducer layer at the bottom of the film stack produces an acoustic wave in response to an excitation beam. A probe beam is reflected from the layer interfaces of the film stack and the acoustic wave to produce an interference signal that encodes data in a time domain from destructive and constructive interference as the acoustic wave propagates upward in the film stack. The data may be analyzed across the time domain to determine the presence and location of one or more non-uniformities in the film stack. An acoustic metrology target may be produced with a transducer layer configured to generate an acoustic wave with a desired acoustic profile based on characteristics of the film stack.

A method and system of nanoscale photoacoustic tomography (nPAT) for non-invasive three-dimensional mapping and characterization of fine cellular structures (such as but not limited to organelles, vesicles, and macromolecules) of biological samples is disclosed.

This disclosure presents a process to determine characteristics of a subterranean formation proximate a borehole. Borehole material can be typically pumped from the borehole, though borehole material can be used within the borehole as well. Extracted material of interest can be collected from the borehole material and prepared for analyzation. Typically, the preparation can utilize various processes, for example, separation, filtering, moisture removal, pressure control, cleaning, and other preparation processes. The prepared extracted material can be placed in a photoacoustic device where measurements can be taken, such as a photoacoustic imager or a photoacoustic spectroscopy device. A photoacoustic analyzer can generate results utilizing the measurements, where the results of the extracted material can include one or more of fracture parameters, fracture plane parameters, permeability parameters, porosity parameters, and composition parameters. The results can be communicated to other systems and processes to be used as inputs.

Disclosed herein is a transparent ultrasonic sensor-based ultrasonic optical composite imaging system including at least one light source and a transparent ultrasonic sensor coaxially aligned with light emitted from the light source and allowing the light emitted from the light source to be transmitted therethrough, wherein the transparent ultrasonic sensor is disposed between the light source and a subject.