Disclosed is an optical sensor device for detecting a chemical analyte including a light source configured to generate probe light having a first wavelength spectrum, an optical fiber sensor probe including a mechanically processed optical fiber segment which is chemically functionalized to include a sensing material formed on exterior of the fiber segment, the optical fiber sensor probe coupled to receive and guide the generated probe light inside the optical fiber sensor probe while allowing optical evanescent coupling between probe light guided inside the optical fiber sensor probe and the sensing material, and a detector coupled to the optical fiber sensor probe to optically detect the guided probe light to obtain information on a material property of the sensing material.

The present invention is directed to a biosensor (10) having a photonic sensing device (20), a sheet of a porous material (60), and an optically clear cover layer (70). The optically clear cover layer (70) may be removable and replaceable, whereby the sheet of porous material (60) can be replaced, and the photonic sensing device (20) can be re-used. Detection devices (810, 910) that include the biosensor (10), as well as methods of making and using the biosensor (10) are also disclosed.

The disclosure provides compositions, kits and methods comprising an absorbent pad comprising a fibrous material and a liquid formulation comprising a luminescent substrate for identifying and quantifying biomolecule analytes.

The disclosure provides compositions, kits and methods comprising an absorbent pad comprising a fibrous material and a liquid formulation comprising a luminescent substrate for identifying and quantifying biomolecule analytes.