A sampling unit includes a needle for aspirating a sample fluid, a housing, and a fitting. The needle includes a needle tip and a needle channel through the needle for guiding the aspirated sample fluid. The needle channel opens at the needle tip. The housing includes a housing cavity and a housing channel opening into the housing cavity. The fitting includes a fitting cavity and a fitting channel. The fitting is configured for sealingly receiving the needle tip into the fitting cavity and for being inserted into the housing cavity, so that the fitting channel on one side fluidically couples to the needle channel and on another side couples to the housing channel.

A particle detection device is provided. The particle detection device may include a substrate and at least one detection unit setting on the substrate. The at least one detection unit may include: a detection pool, configured to accommodate a sample liquid; a sample injection part communicating the detection pool, the sample injection part being sealable with a liquid driving device, wherein the liquid driving device and the sample injection part cooperate to enable the sample liquid to get in and out of the detection pool

A septum contains at least one internal chamber along the central axis of the septum. The chamber provides relief space into which the sealing sections of the septum can deform as a needle passes through the septum. Incorporation of the chamber reduces surface area contact and friction between the septum and needle, which results in reduced septum tearing and reduced production of particulate matter from abrasion.

A sample injector for injecting a fluid into a fluidic path, wherein the sample injector comprises a robot arm configured for moving an injection needle, when being connected to the robot arm, between a fluid container containing the fluid and a seat in fluid communication with the fluidic path, the needle configured for aspirating the fluid from the fluid container, when the needle has been moved to the fluid container, and for injecting aspirated fluid into the fluidic path, when the needle is accommodated in the seat, and the seat configured for accommodating the needle and providing fluid communication with the fluidic path, wherein the robot arm is configured for selectively disconnecting the needle from the robot arm when the needle is accommodated in the seat, and wherein the robot arm is configured for performing a further task while the needle is disconnected from the robot arm.

A seal pack of a sample manager of a liquid chromatography system having a plurality of wash flow pathways fluidically connected to a central pathway that accommodates a sample needle, wherein a first wash flow pathway is vertically offset from a second wash flow pathway, such that a wash solution flows axially along an exterior surface of the sample needle in a vertical direction to wash the sample needle when flowing from the first wash flow pathway to the vertically offset second wash flow pathway, is provided. Furthermore, an autosampler and associated methods are also provided.

A pierceable self-resealing stopper for a container is disclosed. The disclosed stopper is suitable for sealing a container containing reagents for use in a high-throughput analysis system in which reagents in the container are accessed by an aspirator probe piercing the stopper. The stopper is configured for being pierced and resealing itself a large number of times without degradation of the stopper by coring or fragmentation, for example. A set of protrusions extending from a top surface of the stopper is depressed to stretch a thin diaphragm area between the protrusions prior to and during insertion of the probe. After extraction of the probe, the protrusions are allowed to return to a relaxed state, which discontinues stretching of the diaphragm area and reseals the container.

A ferrule includes a deformable portion and a rigid sleeve surrounding at least a portion of the deformable portion. The deformable portion includes between about 5% and about 50% graphite. The deformable portion further includes between about 50% and about 95% polyimide. The rigid sleeve can include a metal, such as stainless steel.

A seal pack of a sample manager of a liquid chromatography system having a plurality of wash flow pathways fluidically connected to a central pathway that accommodates a sample needle, wherein a first wash flow pathway is vertically offset from a second wash flow pathway, such that a wash solution flows axially along an exterior surface of the sample needle in a vertical direction to wash the sample needle when flowing from the first wash flow pathway to the vertically offset second wash flow pathway, is provided. Furthermore, an autosampler and associated methods are also provided.

In order to provide a piston and a syringe with good sliding performance and pressure resistance performance, the piston contained in the syringe that pressurizes or decompresses an internal medium is configured such that a soft portion made of a soft material and a rigid portion made of a material having rigidity higher than rigidity of the soft portion, are connected in series, and arranged such that the soft portion is in contact with the medium and the rigid portion is not in contact with the medium. The soft portion includes a hollow on a surface in contact with the medium. The rigid portion has an end surface facing the soft portion, the end surface including at least an outer peripheral portion in contact with the soft portion. The outer diameter of the soft portion is larger than the outer diameter of the rigid portion, and the outer diameter of the rigid portion is slightly smaller than the inner diameter of an outer cylinder of the syringe.

A gas chromatograph with a positioning system for the inlet liner and the column includes a column and the positioning system for the inlet liner and the column. The column is configured for gas chromatography. Wherein, the positioning system for the inlet liner and the column is configured to position the inlet liner and the column with respect to one another. The positioning system for the inlet liner and the column is configured to repeatably and optimally position the inlet liner and the column with respect to one another. The positioning system for the inlet liner and the column positions the inlet liner in a perpendicular orientation to the column.