A liquid chromatography system including a solvent delivery system, a sample delivery system in fluidic communication with solvent delivery system, a liquid chromatography column located downstream from the solvent delivery system and the sample delivery system, a detector located downstream from the liquid chromatography column, a thermal chamber housing at least one of the solvent delivery system, the sample delivery system, the liquid chromatography column and the detector, an engine configured to control the temperature in the thermal chamber, a heatsink operably connected to the engine, a first temperature sensor in the thermal chamber, a second temperature sensor, and a computer system configured to receive temperature information from each of the first and second temperature sensors, and implement a method for controlling temperature in the thermal chamber.

A first attachment portion to which a packed column is attachable and a second attachment portion to which a chip column is attachable are housed in a column oven. Designation of a temperature of the column oven is received by a designated temperature receiver. In a case in which the chip column is not attached to the second attachment portion, an upper limit temperature of the column oven is set to a first temperature by a setter. An upper limit temperature of the column oven is set to a second temperature lower than the first temperature in a case in which the chip column is attached to the second attachment portion. A temperature of the column oven is adjusted to a received temperature by a temperature adjuster in a case in which the received temperature is equal to or lower than an upper limit temperature.

An improved gas chromatography system is presented. The system comprises: an enclosure having an inlet and an outlet, such that the ventilation flow is from the inlet to the outlet; a chamber disposed in the enclosure; a monolithic gas analyzer disposed in the chamber and a temperature control unit disposed in physical contact with the chamber. The monolithic gas analyzer operates to separate and detect molecules from a gas; whereas, the temperature control unit is configured to control temperature inside the chamber.

The present invention discloses Fuke Qianjin Tablets and a quality control method therefor. The Fuke Qianjin Tablets are made of Radix Et Caulis Flemingiae, Caulis Mahoniae, Herba Andrographis, Zanthoxylum dissitum Hemsl., Caulis Spatholobi, Radix Angelicae Sinensis, Radix Codonopsis, and Radix Rosa Laevigata as raw materials. Each of the Fuke Qianjin Tablets contains not less than 0.008 mg of the genistin, not less than 0.7 mg of the Z-ligustilide, and the total amount of the andrographolide and the dehydroandrographolide is not less than 1.1 mg.

Apparatus and methods for performing chromatography may include a chromatography column and a vacuum insulated jacket having an inner wall and an outer wall. A vacuum area may be formed between the inner wall and the outer wall. The inner wall of the vacuum insulated jacket may surround the chromatography column. A gap may be formed between an outer wall of the chromatography column and the inner wall of the vacuum insulated jacket. The vacuum insulated jacket may extend beyond one or more end frits of the column. The gap may be filled with one or more materials so as to form an insulating or thermal barrier.

The disclosure relates to a gradient twin column recycling chromatography method that is used to separate a mixture containing closely eluting compounds. In one embodiment, a sample includes a primary organic compound and one or more impurities that closely elute with the primary organic compound. A gradient mobile phase is initially used to remove unwanted early eluting and late eluting impurities from the sample. After the gradient removal of some of the impurities is complete, the remaining mixture of the primary organic compound and the closely eluting impurities are separated using recycle chromatography methodology with an isocratic mobile phase.

A column-conditioning enclosure includes a column chamber adapted to hold one or more chromatography separation columns. A duct system provides an airflow path around the column chamber such that the one or more chromatography separation columns held within the column chamber are isolated from the airflow path. An air mover disposed in the airflow path generates a flow of air within the duct system. A heat exchanger system disposed in the airflow path near the air to exchange heat with the air as the air flows past the heat exchanger system. The air circulates through the duct system around the column chamber, convectively exchanging heat with the column chamber to produce a thermally conditioned environment for the one or more chromatography separation columns held within the column chamber.

A column oven includes a main unit, an auxiliary unit, an outside sensor, an internal sensor, a temperature range holding section for holding a plurality of temperature ranges, a temperature range specifying portion for specifying the temperature range to which the outside temperature belongs, a temperature control program holding section for holding a temperature control program for a control method of the main unit and the auxiliary unit in each temperature range in such a way that outputs of the main unit and the auxiliary unit are continuous in the temperature ranges that are adjacent to each other, a control method setting portion for setting a control method of the main unit and the auxiliary unit based on the temperature range specified and the temperature control program, and a temperature control portion for controlling the main unit and the auxiliary unit.

A heating assembly includes a base plate. The heating assembly also includes a heating component coupled to the base plate configured to heat an enclosure of the heating assembly and a fan assembly coupled to the base plate configured to circulate the heated air within the enclosure of the heating assembly.

Techniques are described for accelerating thermal equilibrium in a chromatographic column. An apparatus comprises a chromatography column, and a plurality of temperature control units in thermal contact with the chromatography column. A method of performing liquid chromatography comprises setting an inlet of a chromatography column to a first temperature using a first temperature control unit in thermal contact with said inlet, setting an outlet of the chromatography column to a second temperature using a second temperature control unit in thermal contact with the outlet, wherein the first temperature is less than the second temperature; and injecting a sample into a liquid stream that flows through the chromatography column after the inlet is set at the first temperature and the outlet is at the second temperature.