An improved gas chromatography system is presented. The system comprises: an enclosure having an inlet and an outlet, such that the ventilation flow is from the inlet to the outlet; a chamber disposed in the enclosure; a monolithic gas analyzer disposed in the chamber and a temperature control unit disposed in physical contact with the chamber. The monolithic gas analyzer operates to separate and detect molecules from a gas; whereas, the temperature control unit is configured to control temperature inside the chamber.

A thermal impact assembly for a sample separation apparatus for separating a fluidic sample in a mobile phase by a sample separation unit includes a thermal impact device configured for thermally impacting the fluidic sample and/or the mobile phase and the sample separation unit, and a control unit configured for controlling the thermal impact device for thermally impacting the fluidic sample and/or the mobile phase on the one hand and for thermally impacting the sample separation unit on the other hand independently from each other.

A thermal modulator for a chromatographic system includes a cooler, a thermal valve, a thermal buffer, a heater, and a capillary. The thermal valve thermally-engages the cooler. The thermal buffer thermally-engages the thermal valve. The heater thermally-engages the thermal buffer. The capillary thermally-engages the heater and is configured to transport an analyte in a first direction.

To suppress generation of dew condensation in temperature control space when heating temperature control is performed. In an apparatus, an air temperature control part for cooling or heating air in temperature control space has a first temperature control element for performing at least cooling of air, and a second temperature control element for performing at least heating of air downstream of the first temperature control element. In this manner, when heating temperature control is performed, cooling and dehumidification of air taken in from an air intake portion can be performed by the first temperature control element, and then heating of the dehumidified air can be performed by the second temperature control element.

To suppress inflow of external air through a rack insertion opening while a sample rack is pulled out. An apparatus includes a housing, a temperature control space, and an air temperature control part. The housing has the rack insertion opening on one side surface for putting in and taking out the sample rack. The air temperature control part has an air intake portion for intake of air in the temperature control space, a fan for blowing air taken in from the air intake portion toward the sample rack accommodated in the temperature control space, and a cooling element provided to cool the air on a path of air taken in from the air intake portion. The air temperature control part is configured to reduce an amount of air flowing near the rack insertion opening while the sample rack is pulled out from the temperature control space as compared to while the sample rack is accommodated in the temperature control space, so as to suppress inflow of air through the rack insertion opening.

A method for modulating analytes in a gaseous stream passing through a capillary, wherein the analytes are retained in a trapping zone of the capillary, or allowed to pass therethrough, based on certain conditions. The method includes, during a first time period, heating the trapping zone of the capillary to a first temperature to desorb analytes therewithin and allow the analytes to pass therethrough, and during a second time period, cooling the capillary to a second temperature that is sufficient to trap and focus the analytes within the trapping zone. During the first time period, the method also includes retaining heat at the capillary during to minimize the load on a cooling device thermally connected thereto, and during the second time period, selectively allowing thermal transfer toward the cooling device.

This disclosure relates a device for a chromatographic system, comprising: a chamber defining an internal portion, a capillary disposed within the chamber, the capillary having an input, an output, and an elongate body extending between the input and the output, a cold finger having a first portion in thermal contact with a portion of the elongate body to define a capillary trapping zone, wherein the first portion of the cold finger extends to a second portion that is situated external to the chamber, a heater in thermal contact with the trapping zone of the capillary and configured to transfer heat to the trapping zone, a thermal buffer configured to buffer the heat from the heater into the cold finger and thereby retain the heat within the trapping zone of the capillary, a cooling device arranged external to the chamber and thermally connected to the second portion of the cold finger to define a primary conduction zone, wherein the cooling device is configured to generate a cooling temperature zone at the primary conduction zone, a controller configured to selectively alternate the trapping zone between a cooling temperature by turning off the heat and using the cooling device together with its engagement with the cold finger, and an injection temperature using the heater, wherein the heater alternates between an off state and an on state and a user defined frequency.

A pre-heater assembly for pre-heating a fluid, in particular in a fluid separation apparatus, wherein the pre-heater assembly comprises a capillary having a lumen and being configured for conducting the fluid, and a thermal coupling body contacting at least part of the capillary, having a value of thermal conductivity in a range between 8 W/(m K) and 100 W/(m K) and being arrangable so that heat generated by a heat source is supplied to the capillary via at least part of the thermal coupling body.

A method for modulating analytes in a gaseous stream passing through a capillary, wherein the analytes are retained in a trapping zone of the capillary, or allowed to pass therethrough, based on certain conditions. The method includes, during a first time period, heating the trapping zone of the capillary to a first temperature to desorb analytes therewithin and allow the analytes to pass therethrough, and during a second time period, cooling the capillary to a second temperature that is sufficient to trap and focus the analytes within the trapping zone. During the first time period, the method also includes retaining heat at the capillary during to minimize the load on a cooling device thermally connected thereto, and during the second time period, selectively allowing thermal transfer toward the cooling device.

An arrangement for mounting components in a heating chamber for heating a fluid of a fluid separation apparatus, wherein the arrangement comprises a mounting board having at least one mounting recess each configured for accommodating at least one component, and the at least one component each configured to be mountable in and/or on the at least one mounting recess.