Patent classifications
G01N2030/381
Novel type of extraction cell for a centrifugal partition chromatograph, as well as a centrifugal partition chromatograph containing such an extraction cell
The object of the invention relates to an extraction cell (100) used in a centrifugal partition chromatograph, which has a cell wall (120) determining a closed extraction chamber (150), as well as an inlet (115) and an outlet (140) ensuring the fluid connection between the extraction chamber (150) and the space outside of the extraction cell (100) formed on essentially opposite parts of the cell wall (120).
The extraction cell (100) according to the invention is constructed asymmetrically from the point of view of the reversibility of the direction of flow used when the centrifugal partition chromatograph is in operation.
CENTRIFUGAL-DRIVEN MICROFLUIDIC PLATFORM AND METHOD OF USE THEREOF
In this invention, chromatography is integrated on a centrifugal platform to enable low-cost automated purification. Differing from the traditional chromatography method, purification and separation of a centrifugal compound collecting platform disclosed in the present invention mainly uses a centrifugal force to drive the fluid to flow outward in the radial direction when the motor rotates. The compounds to be separated react with the column packing during the flow, and the compounds with different polarities in the sample are gradually separated. The flow of the fluid can be governed by the motor and the geometry of the fluidic design such that compounds with different characteristics can be separated and collected in different collecting chambers.
METHODS FOR PURIFYING ANTIBODIES
The invention relates to the field of manufacturing recombinant antibody molecules. In particular, methods of purifying such recombinant antibody molecules are provided wherein imidazole or an imidazole-analogue is added during the elution of the recombinant antibody molecule from an affinity chromatography resin, such as a protein-A-based resin.
CPC distribution chromatography of cannabinoids
The invention relates to cannabinoids and their isolation and purification and to obtaining them by means of centrifugal partition chromatography.
CPC DISTRIBUTION CHROMATOGRAPHY OF CANNABINOIDS
The invention relates to cannabinoids and their isolation and purification and to obtaining them by means of centrifugal partition chromatography.
Type of extraction cell for a centrifugal partition chromatograph, as well as a centrifugal partition chromatograph containing such an extraction cell
The object of the invention relates to an extraction cell (100) used in a centrifugal partition chromatograph, which has a cell wall (120) determining a closed extraction chamber (150), as well as an inlet (115) and an outlet (140) ensuring the fluid connection between the extraction chamber (150) and the space outside of the extraction cell (100) formed on essentially opposite parts of the cell wall (120). The extraction cell (100) according to the invention is constructed asymmetrically from the point of view of the reversibility of the direction of flow used when the centrifugal partition chromatograph is in operation.
CPC distribution chromatography of cannabinoids
The invention relates to cannabinoids and their isolation and purification and to obtaining them by means of centrifugal partition chromatography.
CPC DISTRIBUTION CHROMATOGRAPHY OF CANNABINOIDS
The invention relates to cannabinoids and their isolation and purification and to obtaining them by means of centrifugal partition chromatography.
MIXING DISK ASSEMBLY FOR USE ON CENTRIFUGAL PLATFORM
A dynamic mixing disk assembly for a centrifugal platform has an inner disk and an outer disk. The inner disk comprises a first ring part and a second ring part configured to an outer periphery circumference of the first ring part. The first ring part comprises multiple or at least two pawls. The outer disk is rotatably disposed on the second ring part of the inner disk. The outer disk comprises multiple tapered recesses or at least two tapered recesses. When the pawls are engaged with the tapered recesses of the outer disk, the inner disk and the outer disk are able to rotate synchronously with the centrifugal platform. When the inner disk is stopped by the centrifugal platform, the outer disk will keep rotating, and the pawls disengage from the tapered recesses and move to the next tapered recesses.