G01N2035/00702

AUTOMATIC ANALYZING APPARATUS

An automatic analyzing apparatus according to an embodiment includes first and second conveyance paths, a sample dispensing mechanism, and processing circuitry. The first conveyance path conveys a first container rack that holds a container housing the sample. The second conveyance path conveys a second container rack that holds a container housing at least one of a detergent solution for cleaning a probe that dispenses the sample, a diluent for diluting the sample, a buffer solution for mixing the sample, a solution used for a blank test with the sample, and a solution for performing calibration measurement for the apparatus. The sample dispensing mechanism is configured so that the probe can aspirate a liquid in the container of the first container rack and the second container rack. The processing circuitry controls operations of the first conveyance path, the second conveyance path, and the sample dispensing mechanism.

Methods and systems to detect and quantify the amount of LP-X and other abnormal lipoproteins in a biosample using NMR spectroscopy

Described herein are methods and systems for the determination of constituents in biosamples by NMR spectroscopy and more specifically for the determination of lipoprotein constituents LP-X, LP-Y, and LP-Z in blood plasma and serum.

SYSTEMS AND METHODS FOR PROVIDING QUALITY ASSURANCE FOR VALIDATION OF CALIBRATION DATA
20230107733 · 2023-04-06 ·

A system and method for calibration of analytical instruments includes a software application allowing users to compute, construct, display, review, select and evaluate initial calibration models. The software application summarizes the initial calibration using the method evaluation parameters and the user selected evaluation criteria in the initial calibration evaluation table. The software application is a mathematically based program that will independently compute, construct, and display the initial calibration for each target analyte. This program then uses logic functions to review and select calibration variables against evaluation parameters. The software application is a user friendly tool performing all of the calculations independent of the on-boarded software and displays that information on a novel data visualization platform. The software application is the answer to questions centering around software limitations users encounter with on-board instrument software.

AUTOMATIC ANALYSIS DEVICE
20230135949 · 2023-05-04 ·

Provided is an automatic analysis device that estimates causes of change in measurement values of a quality-control substance. An automatic analysis device that analyzes specimens includes an acquisition unit that acquires amount of change in measurement values of a quality-control substance used for quality control, a calculation unit that calculates a change prediction amount on the basis of a difference value in concentration values of a standard solution used for calibration before and after changing lots, and an estimation unit that estimates causes of change occurring in measurement values of the quality-control substance on the basis of results of comparing the amount of change and the change prediction amount.

BLOOD ANALYZING METHOD, BLOOD ANALYZER, CALIBRATOR SET, AND CALIBRATOR SET MANUFACTURING METHOD
20170363651 · 2017-12-21 ·

A method to make it possible to obtain a value related to the amount of DD by FDP measurement. The method includes optically measuring a first calibration sample prepared from an FDP measurement reagent and a first calibrator containing D-dimer (DD) and having a first value relating to the ratio of the content of fibrin/fibrinogen degradation product FDP to the content of DD, acquiring first calculation data based on temporal change of optical information obtained by optical measurement of the first calibration measurement sample, performing optical measurement of a second calibration measurement sample prepared from FDP measurement reagent and a second calibrator containing DD and having a second value that is different from the first value related to the ratio of the content of FDP to the content of DD, acquiring second calculated data based on a temporal change in optical information obtained by optical measurement of the second calibration measurement sample, and acquiring calibration curve information indicating the relationship between the calculation data and the value relating to the amount of DD based on the first calculation data, the second calculation data, the first value, and the second value.

Computerized Fluid Analysis for Determining Whether an Asset is Likely to Have a Fluid Issue
20170292940 · 2017-10-12 ·

Disclosed herein are systems, devices, and methods related to a determination of whether an asset has a fluid issue. In particular, examples involve a platform defining a predictive model for outputting an indicator of whether an asset is likely to have a fluid issue based at least on historical fluid data for one or more assets. The historical fluid data may comprise at least one of a plurality of fluid reports for the one or more assets and an indication of a fluid issue for each fluid report. The platform may receive at least one fluid report associated with a given asset and based at least on the predictive model and the received at least one fluid report, make a determination that the given asset is likely to have a fluid issue. The platform may cause a computing device to output an indication of the determination.

Calibration process and system

An improved calibration process for a medical testing machine. The machine automatically recognizes that a package of calibration material has been inserted into it, and performs a calibration sequence to ascertain a calibration parameter to be used in performing future tests with the medical testing machine. The calibration package may include machine-readable indicators that the package is to be used for calibration, and of a calibration setpoint of a calibration material in the package. A calibration material may be stored in a lyophilized state in the package, and the medical testing machine may automatically reconstitute the lyophilized material.

Measuring apparatus, computer readable medium storing measuring program and measuring method
11199556 · 2021-12-14 · ·

A measuring apparatus includes: a measuring unit to measure a signal value corresponding to a concentration of a specified substance of a first sample; an acquiring unit to acquire a reference value pertaining to the specified substance of a second sample; a calculating unit to calculate a concentration value of the specified substance of the first sample, based on the signal value and the reference value; a timing determination unit to determine timing for calibrating the reference value when satisfying at least one of a first condition that an activity status of a user is a predetermined status and a second condition that a variation in the concentration value of the specified substance of the first sample is equal to or smaller than a threshold value; and an input request unit to request the user to input the reference value at the determined timing.

NDIR gas sensor and optical device

This disclosure provides a highly accurate NDIR gas sensor and a highly accurate optical device even using a simplified optical filter. The NDIR gas sensor and the optical device include: an optical filter having a substrate and a multilayer film on the substrate; and an infrared light emitting and receiving device; where the multilayer film has a structure in which a first layer and a second layer are alternately stacked; the active layer contains Al.sub.xIn.sub.1-xSb or InAs.sub.ySb.sub.1-y; and the optical filter includes a wavelength range having an average transmittance of 70% or more with a width of 50 nm or more in 2400-6000 nm, and has a maximum transmittance of 5% or more in 6000-8000 nm and an average transmittance of 2% or more and 60% or less in 6000-8000 nm.

MULTIVARIATE PROCESS CHART TO CONTROL A PROCESS TO PRODUCE A CHEMICAL, PHARMACEUTICAL, BIOPHARMACEUTICAL AND/OR BIOLOGICAL PRODUCT

Aspects of the application relate to methods, a computer program and a process control device. According to one aspect, a computer-implemented method for determining a multivariate process chart is provided. The multivariate process chart is to be used to control a process to produce a chemical, pharmaceutical, biopharmaceutical and/or biological product. The multivariate process chart includes a first trajectory, an upper limit for the first trajectory and a lower limit for the first trajectory.