The present disclosure provides a device and method of operation thereof relating to a manufacturing test block with a plug that has a contaminant within the plug. The manufacturing test block contains a plurality of apertures and a plug with a contaminant within it that is to be sensed by a detector. Specifically, the present disclosure relates to a manufacturing test block that is customizable in shape to a customer's needs that can be placed on a conveyor system in order to test for contaminants within the conveyor line full of packaged products while not interrupting the other packages.

The invention provides devices that improve tests for detecting specific cellular, viral, and molecular targets in clinical, industrial, or environmental samples. The invention permits efficient detection of individual microscopic targets at low magnification for highly sensitive testing. The invention does not require washing steps and thus allows sensitive and specific detection while simplifying manual operation and lowering costs and complexity in automated operation. In short, the invention provides devices that can deliver rapid, accurate, and quantitative, easy-to-use, and cost-effective tests.

There is provided a nucleic acid extraction method using a cartridge comprising: (a) a driving part of a nucleic acid extraction device is connected to a control rod module disposed in an inner space of the upper body of a piston and a rotation control module coupled to the lower body of the piston; (b) driving the rotation control module and the control rod module, sequentially sucking sample and reagents from the plurality of chambers separated from each other into an interior space, and discharging the mixture of the interior space into the chamber of the cartridge; and (c) driving the rotation control module and the control rod module to suck the reagent inside the master mix bead chamber of the cartridge into the interior space of the piston upper body and then discharge the mixed reagent to a nucleic acid amplification module.

The invention relates to a system with a seal between a manifold and a liquid container in which a sealing without an elastomer material is used, wherein the sealing properties of the seal are independent of the rotational position of the manifold in relation to the container

There is provided a piston of a cartridge for extracting nucleic acids comprising: a cylindrical upper body having a hollow; a lower body having two ports; a control rod module combined to the other end of the upper body to seal the other end and move up and down along the hollow; and a rotation control module that is combined to the shaft of the lower body to transmit a driving force to the lower body.

The invention provides devices that improve tests for detecting specific cellular, viral, and molecular targets in clinical, industrial, or environmental samples. The invention permits efficient detection of individual microscopic targets at low magnification for highly sensitive testing. The invention does not require washing steps and thus allows sensitive and specific detection while simplifying manual operation and lowering costs and complexity in automated operation. In short, the invention provides devices that can deliver rapid, accurate, and quantitative, easy-to-use, and cost-effective tests.

A method for distribution of supports impregnated with antibiotics including positioning a plurality of tubular containers, each one containing a plurality of supports impregnated with antibiotics and stacked, in a corresponding plurality of seats of a dispenser. Extraction of at least a first support from a first container, through an extractor, the extraction being performed in correspondence of an end of the first container and comprising a movement of the first support between a first position inside the first container and a second position extracted from the first container wherein the first support is positioned on an auxiliary dispenser different from the dispenser and configured for housing a plurality of supports in a respective plurality of collection areas. Collection of the first support from the second position using a collector is performed. Transportation of the first support from the auxiliary dispenser towards a culture plate by the collector is performed.

The present invention relates to a sample container handling system (1), having a sample container receptacle (2) and a support element (20). The sample container receptacle (2) in turn has: holding structures (4, 5) which are each configured to hold a respective sample container (3) and which are disposed about a rotation axis (6), and a base (7) having a support region (8) for supporting the sample containers (3) held by way of the holding structures (4, 5), wherein the base (7) furthermore has a side (10) that faces away from the support region (8) and at least one through opening (11) which from this side (10) extends to the support region (8). The support element (20) is connectable to the base (7) of the sample container receptacle (2) in such a manner so as to receive the latter, wherein the support element (20) has at least one protrusion (25, 26, 27) which, when the support element (20) receives the sample container receptacle (2), extends through the at least one through opening (11) and for lifting one or more sample containers (3) projects from the support region (8). The invention furthermore relates to a system having the sample container handling system (1) and a pressure container having a reaction chamber in which the sample container receptacle (2) is able to be received or is received.

A diagnosis system and method for detecting various Volatile Organic Compounds (VOCs) in a biological sample by utilizing a smart platform configured to harness animal bio-sensors trained to detect various VOC's which may indicate various pathologies, and by conducting various data collection practices and analysis methods in order to produce output results. The diagnosis system and method is configured to analyze behavioral parameters concerning the animal bio-sensor and provide a non-invasive and safe diagnostic solution that does not involve exposing a patient to radiation or any other potentially harmful procedure.

An apparatus and method are described for the automated management of bacterial load detector devices to be temporarily positioned inside a clean room, delimited by walls, at least one of which is provided with at least one access aperture on which a primary closing unit is installed, configured to allow access to the inside of the chamber while keeping its atmosphere isolated and separated from the external environment. The apparatus includes a transport container, containing inside it an extractable housing slider on which one or more bacterial load detector devices are positioned, an extraction device configured to extract the slider from the transport container and make it available inside the chamber, and a support device disposed inside the chamber configured to stably position and support the slider.