The invention provides systems and methods for rapid automated identification of microbes and antimicrobial susceptibility testing (AST) directly from a patient specimen, without specimen preparation. Specimens are loaded into an analytical cartridge for processing. Analytical cartridges are preloaded with species-specific labels that are used to identify and enumerate microbes in the specimen. Instruments, such as analyzers can be used to interact with analytical cartridges to carry out methods of the invention all within the cartridge.

Disclosed are a water quality analyzer and a method for analyzing water quality. The water quality analyzer includes a first disc system, a second disc system, a colorimetric system, a cleaning system, a mechanical sampling system, an analysis system and a central control display. The first disc system and the second disc system are axially rotatable. A plurality of sample locating positions and a chemical locating positions are provided on the first disc system along a circumference of the first disc system. A plurality of colorimetric cuvette locating positions are provided on the second disc system, and the colorimetric system is arranged at a circumference edge of the second disc system. The cleaning system and the mechanical sampling system are provided between the first disc system and the second disc system. The method includes water sampling, water sample injection, cleaning, reagent extraction, reagent injection, cleaning and colorimetric analysis.

Provided is an automatic analyzer capable of further reducing carryover between specimens. The automatic analyzer includes a first dispensing unit for dispensing a specimen related to a first analysis item group having a high possibility of carryover, a second dispensing unit for dispensing a specimen related to a second analysis item group having a low possibility of carryover, an input unit for receiving an input of analysis information related to a plurality of analysis items for a specimen, a classification unit for classifying the analysis information into the first analysis item group and the second analysis item group, and a determination unit for determining a dispensing sequence for each specimen for the first analysis item group and determining a dispensing sequence for each analysis item for the second analysis item group.

The present invention relates to a sample container handling system (1), having a sample container receptacle (2) and a support element (20). The sample container receptacle (2) in turn has: holding structures (4, 5) which are each configured to hold a respective sample container (3) and which are disposed about a rotation axis (6), and a base (7) having a support region (8) for supporting the sample containers (3) held by way of the holding structures (4, 5), wherein the base (7) furthermore has a side (10) that faces away from the support region (8) and at least one through opening (11) which from this side (10) extends to the support region (8). The support element (20) is connectable to the base (7) of the sample container receptacle (2) in such a manner so as to receive the latter, wherein the support element (20) has at least one protrusion (25, 26, 27) which, when the support element (20) receives the sample container receptacle (2), extends through the at least one through opening (11) and for lifting one or more sample containers (3) projects from the support region (8). The invention furthermore relates to a system having the sample container handling system (1) and a pressure container having a reaction chamber in which the sample container receptacle (2) is able to be received or is received.

A sample installation part in which a sample container accommodating a sample to be subjected to biochemical analysis is installed, and consumables installation parts in which consumables to be used for the biochemical analysis are installed are accommodated in an apparatus body of a biochemical analysis apparatus. The apparatus body is provided with an opening part that leads to a sample tray. An instruction receiving unit receives a movement instruction for moving the sample tray from a normal position where the sample installation part is disposed on the opening part side to a consumables replenishment position where the consumables installation parts are disposed on the opening part side. A driving control unit moves the sample tray from the normal position to the consumables replenishment position in a case where the movement instruction is received by the instruction receiving unit.

When the consumable is to be conveyed by a reagent gripping mechanism 110 and a reagent conveyance mechanism 111 during analysis of the sample, a control unit operates such that an operation of a device to access the storage unit is stopped, and makes a plan of operation of the reagent gripping mechanism 110 and a reagent conveyance mechanism 111 such that the consumable is conveyed also at a timing at which an operation of the device is stopped, the timing inevitably occurring after the former stop. Accordingly, an automatic analyzer is provided in which occurrence of an unnecessary empty cycle caused when plural consumables are replaced during analysis can be suppressed compared to a prior art.

To provide an automatic analyzer in which a reaction container can be smoothly inserted into a hole of an incubator. An automatic analyzer 100 analyzing a sample includes: an incubator 105 having a hole 202 into which a reaction container 114 containing a mixture of the sample and a reagent is to be inserted; and a transfer unit 109 configured to transfer an unused reaction container 114 to the incubator 105 and insert the reaction container 114 into the hole 202. A lubricating member 203 having a self-lubricating property is provided at an inlet port of the hole 202.

The present disclosure provides an automated sample analyzer having a continuous scanning optical assembly for performing an assay. The optical assembly allows for robust detection of light emitted from a reaction mixture in a dynamically changing environment, such as detection of light from a reaction mixture that is being rotated about an axis at high rotational velocity.

In order to increase efficiency, to minimize the size of the apparatus and in order to reduce the workload of the operator who runs the analyzer, the apparatus for the automated analysis of liquid samples, including a sample tray, at least two reagent trays, at least two reaction trays, and at least two measuring devices. The sample tray is arranged in the center of the analysis area, the at least two reaction trays are arranged adjacent to the sample tray, the at least two reagent trays are arranged adjacent to the reaction trays and the at least two measuring devices are arranged adjacent to the reaction trays. Between the sample disc and each of the at least two reaction trays there is a pipetting device. Between each of the at least two reagent trays and their corresponding reaction trays there is a pipetting device.

The invention provides a version of fluorescent in situ hybridization (FISH) in which all the steps are performed at physiological temperatures, i.e., body temperature, to detect and identify pathogenic bacteria in clinical samples. Methods of the invention use species-specific fluorescent probes to label clinically important infectious bacteria. A sample such as a urine sample is loaded into a cartridge, fluorescently labeled, and imaged with a microscope. Labelled bacteria are pulled down onto an imaging surface and a dye cushion is used to keep unbound probes off of the imaging surface. A microscopic image of the surface shows whether and in what quantities the infectious bacteria are present in the clinical sample.