A drug capsule appearance inspection device is provided having a simplified structure so as to have the effect of inspecting the appearance of drug capsules more rapidly and efficiently and reducing costs. To this end, the device includes: a guide plate (10) having a plurality of capsule accommodating grooves (11) formed therein so that drug capsules (P) can be accommodated; and a bottom friction surface (20) that allows the drug capsules (P) to rotate by friction when the guide plate (10) moves horizontally.

Arrays of integrated analytical devices are provided. The arrays are useful in the analysis of highly multiplexed optical reactions in large numbers at high densities, including biochemical reactions, such as nucleic acid sequencing reactions. In particular, the arrays provide increased efficiency of optical collection and decreased background signal as the lateral dimensions of the unit cell of devices within the array are decreased, for example as they are decreased to 2 μm, or even less.

A detecting method includes irradiating a substrate having a concave and convex shape, with laser light collected by a lens; and detecting a height difference of the concave and convex shape by acquiring light intensity of reflected light and/or scattered light from the substrate as image data, and a light irradiation surface of the substrate is arranged at a position closer to the lens than a focal position of the lens is, reflected light and/or scattered light from the light irradiation surface is received as detected light, and a height difference of the substrate is detected based on a change in intensity of the received light.

The method of analyzing one or more samples arranged in sample receptacles of a platform that is configured to receive a plurality of separate samples includes the steps of measuring electromagnetic radiation transmitted or emitted by each sample, repeating the measurement a plurality of times at predetermined intervals, on the basis of each measurement, forming a result matrix comprising a plurality of cells, each cell of the result matrix corresponding to a sample receptacle of the plat-form, wherein a measurement value of each sample is used as an input for determining the visual properties of the respective cell in the result matrix, and displaying the results as consecutive matrixes in respect of time.

Provided herein are methods of determining molecular binding kinetics on particles, such as magnetic nanoparticles. In some embodiments, the methods include introducing an incident light from a light source toward a sample container that comprises a particle-bound biomolecule-ligand composition comprising a plurality of particle-bound biomolecules and a plurality of ligands that binds, or is capable of binding, to biomolecules of the plurality of particle-bound biomolecules, detecting light scattered from particle-bound biomolecule-ligand complexes in the particle-bound biomolecule-ligand composition over a duration to produce a set of imaging data using the detector, and determining size or volume changes of one or more of the particle-bound biomolecule-ligand complexes during at least a portion of the duration from the set of imaging data to thereby determine the molecular binding kinetics on the particles. Related systems and computer readable media are also provided.

A method for characterizing compounds of interest, introduced into a measuring chamber of an electronic nose, includes injecting a first gas sample formed from a carrier gas without the compounds of interest forming a second gas sample from the carrier gas with the compounds of interest; determining a measurement signal (S.sub.k(t.sub.i)); measuring values φ1, φ2 of the relative humidity; determining corrective parameter ({tilde over (S)}.sub.k.sup.ref|.sub.φ2; ΔS.sub.k.sup.ref|.sub.Δφ); and determining a useful signal (Su.sub.k(t.sub.iϵP2)) by correcting the measurement signal associated with the second gas sample using the determined corrective parameter, and characterizing the compounds of interest based on the useful signal.

A method for measuring molecular interactions on a plurality of regions of interest (ROIs) of a sensor surface of a biosensor device. The method can include receiving respective biosensor response data for each ROI of the plurality of ROIs. The method further can include determining a sample group and a reference group for the plurality of ROIs. The sample group can include sample group ROIs of the plurality of ROIs, and the reference group can include reference group ROIs of the plurality of ROIs. The method also can include generating one or more sample data distributions based on one or more respective sample group binding parameters for each of the sample group ROIs derived from the respective biosensor response data for the each of the sample group ROIs. The method further can include generating one or more reference data distributions based on one or more respective reference group binding parameters for each of the reference group ROIs derived from the respective biosensor response data for the each of the reference group ROIs. Other embodiments are disclosed.

The invention relates to a system (15) for observing a plate (10) including wells (20), including, for each well (20): a source (40) comprising a light-emitting diode (60) capable of producing a light ray, a pinhole (70), and a light integrator (65), an optical sensor (185) able to collect the optical signal from the well (20), the system (15) being such that: a ratio between the length and the average transverse dimension (Dt) of each light integrator (65) is greater than or equal to 2.2, or at least one optical axis is off-centered relative to the propagation line, the ratio between the length and the average transverse dimension of the integrator being greater than or equal to 1.5.

A process for detecting foreign objects in a food-containing product stream comprises: forwarding the product stream, illuminating the product stream, generating raw data based on electromagnetic energy reflected from the product stream using a camera, and processing the raw data to generate classified image data corresponding with food product, foreign object(s), and background. A system for detecting foreign objects in the product stream comprises a forwarding device, an illuminator, a camera, and instructions in memory that form image data and classify the data as corresponding with food product, foreign objects, and background.

The method of analyzing one or more samples arranged in sample receptacles of a platform that is configured to receive a plurality of separate samples includes the steps of measuring electromagnetic radiation transmitted or emitted by each sample, repeating the measurement a plurality of times at predetermined intervals, on the basis of each measurement, forming a result matrix comprising a plurality of cells, each cell of the result matrix corresponding to a sample receptacle of the plat-form, wherein a measurement value of each sample is used as an input for determining the visual properties of the respective cell in the result matrix, and displaying the results as consecutive matrixes in respect of time.