Disclosed sensors can include at least one resonator (in some embodiments, at least two resonators) and various other structures that may be formed in association with the resonators. The at least one resonator in embodiments can include a bottom electrode, a piezoelectric layer, and a top electrode, wherein the piezoelectric layer is positioned between the bottom electrode and the top electrode.

According to improvement of the receptor layer of various sensors of the type for detecting physical parameters (for example, a surface stress sensor, QCM, and SPR), all of high sensitivity, selectivity, and durability are achieved simultaneously. A porous material or a particulate material, e.g., nanoparticles, is used in place of a uniform membrane which has been conventionally used as a receptor layer. Accordingly, the sensitivity can be controlled by changing the membrane thickness of the receptor layer, the selectivity can be controlled by changing a surface modifying group to be fixed on the porous material or particulate material, and the durability can be controlled by changing the composition and surface properties of the porous material or particulate material.

In one example, a method performed by electronic circuitry comprises: causing a transducer to transmit a first signal; receiving a second signal from the transducer; computing distances responsive to a time between the first and second signals; determining a vibration characteristic based on the distances; reading reference vibration characteristics from data in a memory; comparing the input vibration characteristic to the reference vibration characteristics; and responsive to the comparing, performing at least one of: providing a signal representing a status of the comparing; or updating the data in the memory.

A method of operating an acoustic resonance fluid flow sensor. The method comprises emitting an acoustic stimulus signal comprising a plurality of frequencies into an acoustic resonance cavity of the acoustic resonance fluid flow sensor, sensing an acoustic response signal within the acoustic resonance cavity and deriving the phases or equivalent group delays of one or more frequency components of a frequency spectrum of the acoustic response signal.

The illustrated embodiments include a method of operating a SAW sensor to detect a sample in a fluid which includes the steps of: providing a SAW sensor with a functionalized detection lane in a handheld, portable assay device and sensor system; maintaining the functionalized detection lane of the SAW sensor dry until the sample is fluidically disposed in the detection lane; fluidically disposing the sample in the functionalized detection lane; removing fluid the functionalized detection lane to concentrate the sample in the functionalized detection lane to increase the probability of a specific antibody-antigen interaction; washing the functionalized detection lane so that substantially only the specific antigen-antibody interaction remains in the functionalized detection lane; removing fluid from the functionalized detection lane again; and measuring concentration of the sample while the functionalized detection lane is fluid-free.

Disclosed herein are oligomeric machines comprising a first oligomeric module having a first end and a second end, and a second oligomeric module having a first end and a second end; wherein the first end of the first oligomeric module is joined to the first end of the second oligomeric module; and wherein the oligomeric machine exhibits stochastic resonance and/or spontaneous vibrations in a solution at a temperature when the temperature is in a critical temperature range and the oligomeric machine does not exhibit stochastic resonance in the solution when the temperature is not in the critical temperature range; and the oligomeric machine exhibits stochastic resonance and/or spontaneous vibrations in a solution under a force load applied to the oligomeric machine when the force load is in a critical force range and the oligomeric machine does not exhibit stochastic resonance and/or spontaneous vibrations in the solution when the force load is not in the critical range. Also disclosed herein are molecular sensors comprising an oligomeric machine and configured to bind with one or more analytes thus modulating the stochastic resonance and/or spontaneous vibrations of the oligomeric machine. Additionally disclosed are uses of molecular sensors for the detection of one or more analytes in a solution.

Object analysis comprising measuring a frequency-dependent natural oscillation behavior of the object by dynamically-mechanically exciting the object in a defined frequency range (f) by means of generating a body oscillation by applying a test signal, and detecting a body oscillation generated in the object on account of the exciting. Moreover, the method involves simulating a frequency-dependent natural oscillation behavior for the object by generating a virtual digital representation of the object, and carrying out a finite element analysis on the basis of the virtual representation comprising dynamically exciting, in a simulated manner, the virtual representation into a virtual frequency range for generating a virtual body oscillation, calculating the virtual body oscillation generated in the object on account of the exciting in a simulated manner, and deriving an object state on the basis of a comparison of the measured natural oscillation behavior and the simulated frequency-dependent natural oscillation behavior.

A battery system comprising: an anode composed of a non-toxic biocompatible metal; a first printable carbon-based current collector comprising biocompatible multiple few layer graphene (FLG) sheets in electrical contact with and extending from the anode; a three-dimensional (3D) hierarchical mesoporous carbon-based cathode including an open porous structure configured to catalyze an active material via gas diffusion; a polymer-based barrier film deposited on the 3D hierarchical mesoporous carbon-based cathode, the polymer-based barrier film configured to prevent oxygen from entering the open porous structure while deposited on the 3D hierarchical mesoporous carbon-based cathode; a second printable carbon-based current collector comprising biocompatible multiple few layer graphene (FLG) sheets in electrical contact with and extending from the cathode; and an electrolyte layer disposed between the anode and the cathode, the electrolyte layer configured to activate the battery system when released into one or both of the anode and the cathode.

A method is provided including the steps: —first excitation of the object via a multifrequency signal; —detecting a first response signal of the object at one or multiple measuring points at the object; —transforming the first response signal from a time range into a frequency-dependent range; —selecting one or multiple frequencies, based on the frequency-dependent range; —second excitation of the object based on the selected frequencies; —detecting a second response signal of the object at one or multiple measuring points of the object; —ascertaining a mechanical parameter based on the second response signal.

A microorganism test method includes: covering, with a hydrophobic capping solvent, a sample containing a specimen and a liquid culture medium, within a region in a vicinity of a sensor configured to detect a microorganism contained in the specimen; and calculating, based on an output from the sensor, information indicating a degree of growth of the microorganism contained in the specimen. For example, an analysis unit drives an array sensor in which many resonators are arranged in a matrix pattern, stores a resonance frequency of a resonator which is acquired at the time of starting the measurement as an initial frequency, and calculates a difference (frequency shift) between the initial frequency and a resonance frequency of the resonator which is measured at predetermined time intervals as information indicating a degree of growth of the microorganism contained in the specimen.