A solid state electrolyte and method of preparation is provided. The solid state electrolyte includes a plasticized polymer matrix with non-dissolved salt crystals embedded in the polymer matrix and wherein the non-dissolved crystals are suitable for dissolving ions in the plasticized polymer. The method of preparation includes dissolving a plasticizer and a polymer matrix in an organic solvent to obtain a plasticized polymer matrix; and mixing the salt crystals with the plasticized polymer matrix, wherein the weight ratio of salt crystals versus plasticizer and polymer matrix and organic solvent is above saturation concentration such that non-dissolved salt crystals are embedded in the plasticized polymer matrix.

Embodiments are directed to a chemical sensor and a method of fabricating a chemical sensor that includes a membrane having full circumferential adhesion. The chemical sensor device includes a silicon substrate comprising a sensor-side and a backside. The sensor-side includes a sensor-side electrode; a first passivation layer disposed on the substrate; and a second passivation layer on the first passivation layer and adjacent to the sensor-side electrode, the passivation layer comprising an adhesion trench exposing a portion of the first passivation layer, and a polyimide ring disposed on the second passivation layer. The backside includes a backside electrode on the backside of the substrate. The substrate includes an electrically isolated doped region, such as a through silicon via, electrically connecting the sensor-side electrode and the backside electrode.

An electrochemical sensor with an ion-selective membrane that comprises a crosslinked alkyl methacrylate homopolymer or copolymer of two or more alkyl methacrylates 1. with a covalently attached electrically neutral or electrically charged ionophore that is selective for a target cation or anion, or 2. with a covalently attached cationic or anionic ionic site, or 3. with a covalently attached cationic or anionic ionic site and covalently attached electrically neutral or electrically charged ionophore.

A sensing platform for continuous water resource monitoring by electrochemical detection and solution parameter correction is provided. The sensing platform employs a solid-state electrolyte three-electrode cell, creating a high ionic strength environment within the solid-state electrolyte membrane, which is in ion exchange equilibria with the sampled solution. This device may be used as a standalone sensor in environments where the water parameters (pH temperature, and ionic strength) are controlled, or in concert with compensation sensors where water parameters are not controlled.

A method of and an apparatus for manufacturing a measuring cell comprising a tube having a first end capped by a membrane of an ion-selective material, comprising the steps of: providing a paste comprising all constituents of the ion-selective material; mounting the tube onto a stick with a tip such that the stick extends through the tube; dispensing an amount of the paste onto the tip; heating the first end of the tube and the dispensed paste to a temperature causing the dispensed paste to melt and the thus-produced melt to form a film covering the tip and an end surface of the first end of the tube; transforming the film into the membrane joined to the tube by cooling the first end of the tube and the film to a temperature below a melting point of the ion-selective material; and separating the thus-manufactured measuring cell from the stick.

A method for producing a polymer membrane for the potentiometric detection of an analyte, the method comprising the following successive steps: providing a formulation comprising a dissolved polymer, an ion exchanger, an ionophore, optionally a plasticiser, and a solvent selected from glycol ethers and acetates thereof, and glycol diacetates, depositing the formulation on a support, for example a transducer, and evaporating the solvent, so as to form a polymer membrane.

A method of manufacturing membranes consisting essentially of an ion-selective material is disclosed. The method comprises: providing a spreadable base material; dispensing a quantity of the base material onto a top side of a tray, wherein the top side includes a set of coplanar flat surface segments, each having a surface area corresponding to a disc area of one of the membranes to be manufactured, and wherein at least the top side of the tray consists essentially of a non-adhesive material; distributing the dispensed base material across the top side of the tray such that a thickness of the distributed base material covering the coplanar surface segments corresponds to a predetermined thickness; transforming the thus-distributed base material into ion-selective material comprising one or more coplanar sheets covering the coplanar surface segments; and removing individual membranes from the tray, each defining a disc-shaped section of the ion-selective material.

The present patent disclosure concerns a sensor device comprising a sensor electrode for measuring an analyte concentration in an aqueous solution and a method of preparing a sensor electrode, wherein the sensor electrode comprises a substrate having conductive means, a polymer mixture deposited on the sensor electrode adjacent to and/or in contact with the conductive means, wherein the polymer mixture comprises a semiconducting polymer comprised of monomeric units comprising one or more aromatic, preferably thiophene, moieties along a backbone chain and at least two polar side chains covalently bonded to the backbone chain, wherein the semiconducting polymer has an electron and/or hole mobility of at least 1×10.sup.−2 cm.sup.2V.sup.−1s.sup.−1, preferably at least 1×10.sup.−1 cm.sup.2V.sup.−1s.sup.−1, and wherein the polymer mixture further comprises a hydrophilic polymer comprised of monomeric units comprising one or more carbon-carbon bonds and one or more of hydroxyl, ester, carbonyl or amide moieties, wherein the semiconducting polymer to hydrophilic polymer weight ratio ranges from 1:100 to 1:1, wherein the hydrophilic polymer is cross-linked with a mole ratio of cross-linked hydrophilic polymer monomer units to non cross-linked hydrophilic polymer ranging from 1 to 25%.

A strip structure for measuring potassium ions includes: a strip having an inner space for receiving a solution therein and being formed in a plate shape; an inlet formed in the strip and capable of injecting a solution into the inner space of the strip; a potassium ion selective membrane arranged in the inner space and capable of permeating potassium ions of the solution; and a first working electrode extending in a strip shape, wherein one side of the first working electrode is arranged inside the potassium ion selective membrane and the other side of the first working electrode is on a surface of the strip.

A prosthetic device includes a closed loop system for maintaining a predetermined concentration of a target ion in a region in proximity to a cell, such as a nerve cell. The device includes a controller and an ion-selective electrode assembly operatively connected to the controller, wherein the ion-selective electrode configuration is configured to sense the concentration of the target ion by potentiometric measurement and to convey the concentration to the controller. The controller is configured to modulate the current to the ion-selective electrode assembly based on the concentration of the target ion to control the concentration of the target ion so as to maintain the predetermined concentration of the target ion.