Patent classifications
G01N27/76
Method and apparatus for detecting superparamagnetic material
The invention relates to a method and apparatus for detecting superparamagnetic material. The method comprises applying, by an excitation coil, a magnetic field during a first period to an object to modulate a magnetization of the superparamagnetic material, the magnetic field comprising a first component with a first frequency; positioning a sensing device at a first position from the excitation coil receiving a first signal by a first detection sub-coil in the sensing device and a second signal by a second detection-sub-coil in the sensing device; determining a sensor signal from the first signal and the second signal; determining a detection signal based on the sensor signal; determining a parameter indicating an amount of superparamagnetic material by dividing the detection signal by the first signal, and repeating steps to at at least one different position in order to determine a location where the parameter has a maximal value.
DEVICES AND METHOD FOR EVALUATING THE INTEGRITY OF SOIL BEHIND AN INFRASTRUCTURE
There is disclosed a device for use in evaluating the integrity of soil behind a wall of an infrastructure. The device generally has a frame having a plurality of rests adapted to be received onto the wall during use; a hammer assembly having an actuator fixedly mounted to the frame and a hammer element having a head movably mounted to the frame, the actuator being actuatable to move the head to strike the wall while the plurality of rests hold the frame in a fixed position relative to the wall; and a sensor configured and adapted to sense vibrations of a portion of the wall resulting from the strike and to generate a vibration signal indicative thereof.
DEVICES AND METHOD FOR EVALUATING THE INTEGRITY OF SOIL BEHIND AN INFRASTRUCTURE
There is disclosed a device for use in evaluating the integrity of soil behind a wall of an infrastructure. The device generally has a frame having a plurality of rests adapted to be received onto the wall during use; a hammer assembly having an actuator fixedly mounted to the frame and a hammer element having a head movably mounted to the frame, the actuator being actuatable to move the head to strike the wall while the plurality of rests hold the frame in a fixed position relative to the wall; and a sensor configured and adapted to sense vibrations of a portion of the wall resulting from the strike and to generate a vibration signal indicative thereof.
Well Monitoring with Optical Electromagnetic Sensing System
A method of monitoring a substance in a well can include disposing at least one optical electromagnetic sensor and at least one electromagnetic transmitter in the well, and inducing strain in the sensor, the strain being indicative of an electromagnetic parameter of the substance in an annulus between a casing and a wellbore of the well. A system for monitoring a substance in a well can include at least one electromagnetic transmitter, and at least one optical electromagnetic sensor with an optical waveguide extending along a wellbore to a remote location, the sensor being positioned external to a casing in the wellbore.
SYSTEM AND METHOD FOR CELL LEVITATION AND MONITORING
Magnetic cell levitation and cell monitoring systems and methods are disclosed. A method for separating a heterogeneous population of cells is performed by placing a microcapillary channel containing the heterogeneous population of cells in a magnetically-responsive medium in the disclosed levitation system and separating the cells by balancing magnetic and corrected gravitational forces on the individual cells. A levitation system is also disclosed, having a microscope on which the microcapillary channel is placed and a set of two magnets between which the microcapillary channel is placed. Additionally, a method for monitoring cellular processes in real-time using the levitation system is disclosed.
SYSTEM AND METHOD FOR CELL LEVITATION AND MONITORING
Magnetic cell levitation and cell monitoring systems and methods are disclosed. A method for separating a heterogeneous population of cells is performed by placing a microcapillary channel containing the heterogeneous population of cells in a magnetically-responsive medium in the disclosed levitation system and separating the cells by balancing magnetic and corrected gravitational forces on the individual cells. A levitation system is also disclosed, having a microscope on which the microcapillary channel is placed and a set of two magnets between which the microcapillary channel is placed. Additionally, a method for monitoring cellular processes in real-time using the levitation system is disclosed.
Particle analyzing apparatus, particle separating device, particle analysis method, and particle separating method
A particle analyzing apparatus (10) includes a processor (42) and storage (41). The processor (42) acquires a volume magnetic susceptibility of an analyte particle (p). The storage (41) stores reference data (43). The reference data (43) indicates a volume magnetic susceptibility of a reference particle of the same type as a type of the analyte particle (p) for each of possible crystal forms of the analyte particle (p). The processor (42) determines a crystal form of the analyte particle (p) on the basis of the volume magnetic susceptibility of the analyte particle (p) and the reference data (43).
Giant magnetoresistance-based biosensors
Disclosed is a system for detecting one or more target analytes which includes a resistor structure comprised of a substrate, a graphene-based nanocomposite material located on a surface of the substrate with the graphene-based nanocomposite material exhibiting one or more magnetoresistance properties. A surface of the nanocomposite material includes molecular sensing elements bound thereto which exhibit an affinity for binding with the target analytes. Electrodes are connected to the resistor structure connectable to a power source and a device for measuring a resistance across the resistor structure for sensing a giant magnetoresistance (GMR) value of the resistor structure. Included are magnetic colloidal nanoparticles exhibiting preselected magnetic properties with an outer surface of the magnetic colloidal nanoparticles being modified to allow interaction with the surface of the resistor structure resulting in a change in the GMR value of the resistor structure. The resistor structure is configured to be operably connected to a magnetic field generating device configured to apply a magnetic field to the graphene-based nanocomposite wherein the field has a magnitude in a range from greater than 0 to about 5 Tesla. A presence of target analytes in a vicinity of the surface of the resistor structure induces the interaction to occur by binding of the target analytes to the molecular sensing elements bound thereto causing a change in GMR value of the resistor structure.
Giant magnetoresistance-based biosensors
Disclosed is a system for detecting one or more target analytes which includes a resistor structure comprised of a substrate, a graphene-based nanocomposite material located on a surface of the substrate with the graphene-based nanocomposite material exhibiting one or more magnetoresistance properties. A surface of the nanocomposite material includes molecular sensing elements bound thereto which exhibit an affinity for binding with the target analytes. Electrodes are connected to the resistor structure connectable to a power source and a device for measuring a resistance across the resistor structure for sensing a giant magnetoresistance (GMR) value of the resistor structure. Included are magnetic colloidal nanoparticles exhibiting preselected magnetic properties with an outer surface of the magnetic colloidal nanoparticles being modified to allow interaction with the surface of the resistor structure resulting in a change in the GMR value of the resistor structure. The resistor structure is configured to be operably connected to a magnetic field generating device configured to apply a magnetic field to the graphene-based nanocomposite wherein the field has a magnitude in a range from greater than 0 to about 5 Tesla. A presence of target analytes in a vicinity of the surface of the resistor structure induces the interaction to occur by binding of the target analytes to the molecular sensing elements bound thereto causing a change in GMR value of the resistor structure.
Magnetic field generation device, measurement cell, analysis apparatus, and particle separation device
A magnetic field generation device (100) includes a first magnet (1), a second magnet (2), and a position adjustment mechanism (5). The second magnet (2), together with the first magnet (1), generates a magnetic field. The position adjustment mechanism (5) adjusts a position of the first magnet (1). The magnetic field generation device (100) controls the value of the product of a magnetic flux density and a magnetic flux density gradient in the magnetic field through the adjustment of the position of the first magnet (1) by the position adjustment mechanism (5).