A gas chromatograph is provided with: a sample gas generator (2) configured to generate a sample gas from an injected sample; a separation column (6) fluidly connected to an outlet of the sample gas generator, the separation column (6) being configured to separate components in the sample gas generated by the sample gas generator (2); a detector (8) fluidly connected to an outlet of the separation column (6), the detector (8) being configured to detect the components separated in the separation column (6); a plurality of gas supply sources (12A, 12B) each configured to supply a carrier gas for carrying the sample gas generated by the sample gas generator to the separation column (6); a switching unit (12A, 12B) fluidly connected to the plurality of gas supply sources, the switching unit being configured to switch such that one of the plurality of gas supply sources is fluidly connected to the sample gas generator (2); a regulator (16) interposed between the switching unit (14) and the sample gas generator (2), the regulator (16) being configured to regulate a gas supply pressure from the gas supply source (12A, 12B) and a gas supply flow rate to the sample gas generator (2); and a control unit (30) configured to control an operation of the regulator (16), wherein the control unit (30) is configured such that in a case where the gas supply source fluidly connected to the sample gas generation unit has been changed in order to shift to a standby state capable of performing subsequent sample analysis and that at least a gas type of the carrier gas supplied to the supply gas generation unit (2) has been changed, the control unit (30) performs a replacement promotion operation for putting the gas supply pressure, the gas supply flow rate, or a combination thereof to a state different from the standby state to promote a gas replacement in the flow path for the carrier gas.

A gas chromatograph is provided with: a sample gas generator (2) configured to generate a sample gas from an injected sample; a separation column (6) fluidly connected to an outlet of the sample gas generator, the separation column (6) being configured to separate components in the sample gas generated by the sample gas generator (2); a detector (8) fluidly connected to an outlet of the separation column (6), the detector (8) being configured to detect the components separated in the separation column (6); a plurality of gas supply sources (12A, 12B) each configured to supply a carrier gas for carrying the sample gas generated by the sample gas generator to the separation column (6); a switching unit (12A, 12B) fluidly connected to the plurality of gas supply sources, the switching unit being configured to switch such that one of the plurality of gas supply sources is fluidly connected to the sample gas generator (2); a regulator (16) interposed between the switching unit (14) and the sample gas generator (2), the regulator (16) being configured to regulate a gas supply pressure from the gas supply source (12A, 12B) and a gas supply flow rate to the sample gas generator (2); and a control unit (30) configured to control an operation of the regulator (16), wherein the control unit (30) is configured such that in a case where the gas supply source fluidly connected to the sample gas generation unit has been changed in order to shift to a standby state capable of performing subsequent sample analysis and that at least a gas type of the carrier gas supplied to the supply gas generation unit (2) has been changed, the control unit (30) performs a replacement promotion operation for putting the gas supply pressure, the gas supply flow rate, or a combination thereof to a state different from the standby state to promote a gas replacement in the flow path for the carrier gas.

A sample input interface for inputting samples into a detecting unit of an in-vitro diagnostic analyzer. The sample input interface comprises a sample input port comprising an outer input-port side configured for plugging-in an open end of a sample container and an inner input-port side, an aspiration needle comprising an upstream end and a downstream end, where the downstream end is fluidically connected or connectable to the detecting unit and where the upstream end is configured to alternately couple to the inner input-port side and to a fluid supply port. The outer input-port side is further configured to alternately couple to a fluid supply port while the upstream end of the aspiration needle is coupled to the inner input-port side in order to rinse the sample input port with fluid aspirated by the aspiration needle from a fluid supply unit via the sample input port.

A sample input interface for inputting samples into a detecting unit of an in-vitro diagnostic analyzer. The sample input interface comprises a sample input port comprising an outer input-port side configured for plugging-in an open end of a sample container and an inner input-port side, an aspiration needle comprising an upstream end and a downstream end, where the downstream end is fluidically connected or connectable to the detecting unit and where the upstream end is configured to alternately couple to the inner input-port side and to a fluid supply port. The outer input-port side is further configured to alternately couple to a fluid supply port while the upstream end of the aspiration needle is coupled to the inner input-port side in order to rinse the sample input port with fluid aspirated by the aspiration needle from a fluid supply unit via the sample input port.

A liquid chromatograph includes: an analysis column; a sample loop that temporarily contains a mixed liquid of a sample and a mixture solvent; and a passage switch valve capable of switching a passage between a load position where the mixed liquid is temporarily held in the sample loop and an injection position where the mixed liquid held in the sample loop is sent to the analysis column. In the liquid chromatograph, a specific passage is formed in each of the load position and the injection position.

The present invention is a data-processing device used for a chromatograph which continuously performs a series of analyses for components in each sample while sequentially introducing a plurality of samples into a column. The device includes: an input section configured to allow for input of information into a schedule table for a plurality of analyses, the schedule table describing an analysis condition including a combination of the values of a plurality of control parameters, the order of execution of the plurality of analyses, and information for identifying a sample to be subjected to each analysis; a chromatogram creating means configured to receive data sequentially collected during two or more analyses and create a joint chromatogram from the data if the two or more analyses have been continuously performed for the same sample according to the schedule table; and a display means configured to display the joint chromatogram.

The present invention relates to a method of measuring at least one product quality attributes, including critical quality attributes (e.g., oxidation, C-terminal lysine, aggregation, N-terminal glutamine cyclization.) by an online liquid chromatography system, wherein the liquid chromatography system is running a hydrophobic interaction chromatography (HIC) method.

The present invention relates to a method of measuring at least one product quality attributes, including critical quality attributes (e.g., oxidation, C-terminal lysine, aggregation, N-terminal glutamine cyclization.) by an online liquid chromatography system, wherein the liquid chromatography system is running a hydrophobic interaction chromatography (HIC) method.

First analysis information including at least one of a sample analysis condition, a sample preparation condition and a kind of sample is assigned to at least one kind of jig, and the jig is arrangeable to correspond to any of a plurality of sample holders. Holding information representing whether a sample is held by each sample holder and jig information for identifying the kind of jig are acquired by a first information acquirer from an automatic sample injector. The first analysis information in regard to a corresponding sample holder is specified by a first analysis information specifier based on jig information. A batch file for controlling a sequence of analysis or preparation in regard to a sample held by a sample holder corresponding to a jig is created by a batch file creator with use of the holding information and the first analysis information.

First analysis information including at least one of a sample analysis condition, a sample preparation condition and a kind of sample is assigned to at least one kind of jig, and the jig is arrangeable to correspond to any of a plurality of sample holders. Holding information representing whether a sample is held by each sample holder and jig information for identifying the kind of jig are acquired by a first information acquirer from an automatic sample injector. The first analysis information in regard to a corresponding sample holder is specified by a first analysis information specifier based on jig information. A batch file for controlling a sequence of analysis or preparation in regard to a sample held by a sample holder corresponding to a jig is created by a batch file creator with use of the holding information and the first analysis information.