Provided is a chromatograph mass spectrometer that includes a component separation unit 13 that temporally separates components in a sample, a first detector 15 that acquires measurement data of components included in an outflowing liquid from the component separation unit 13 by an analysis method different from mass spectrometry, a mass spectrometer 2 that acquires mass spectrometry data including intensity information for each of mass-to-charge ratios of ions derived from the components contained in the outflowing liquid from the component separation unit 13, a chromatogram creation unit 45 that creates a chromatogram representing an intensity change of the measurement data with time based on the measurement data of the first detector 15, an information extraction unit 46 that detects a peak based on the intensity change of the mass spectrometry data with time, and extracts information including a representative time of the peak, and a chromatogram display unit 48 that displays the chromatogram together with additional information corresponding to the extracted time.

A method to simulate distillation of a petroleum stream by gas chromatography can include separating the petroleum stream with a gas chromatograph as a function of boiling point; passing the separated petroleum stream through a vacuum ultraviolet detector to yield data comprising a vacuum ultraviolet signal as a function of boiling point; integrating the vacuum ultraviolet signal as a function of boiling point over two or more wavelength ranges to derive relative concentrations of two or more components of the separated petroleum stream that correspond to the two or more wavelength ranges.

A method to simulate distillation of a petroleum stream by gas chromatography can include separating the petroleum stream with a gas chromatograph as a function of boiling point; passing the separated petroleum stream through a vacuum ultraviolet detector to yield data comprising a vacuum ultraviolet signal as a function of boiling point; integrating the vacuum ultraviolet signal as a function of boiling point over two or more wavelength ranges to derive relative concentrations of two or more components of the separated petroleum stream that correspond to the two or more wavelength ranges.

Provided is a chromatograph mass spectrometer that includes a component separation unit 13 that temporally separates components in a sample, a first detector 15 that acquires measurement data of components included in an outflowing liquid from the component separation unit 13 by an analysis method different from mass spectrometry, a mass spectrometer 2 that acquires mass spectrometry data including intensity information for each of mass-to-charge ratios of ions derived from the components contained in the outflowing liquid from the component separation unit 13, a chromatogram creation unit 45 that creates a chromatogram representing an intensity change of the measurement data with time based on the measurement data of the first detector 15, an information extraction unit 46 that detects a peak based on the intensity change of the mass spectrometry data with time, and extracts information including a representative time of the peak, and a chromatogram display unit 48 that displays the chromatogram together with additional information corresponding to the extracted time.

An analytical instrument assembly includes a gas chromatograph, a first detector, a second detector, and a pneumatic control module. The gas chromatograph includes a flow splitter configured to receive a sample. The first detector is coupled to the flow splitter. The second detector is coupled to the flow splitter. The pneumatic control module is coupled to the flow splitter and configured to deliver a carrier gas to the flow splitter. The flow splitter is configured to split the sample and deliver at least a first portion of the sample to the first detector and at least a second portion of the sample to the second detector at a first split ratio. The pneumatic control module is configured to deliver one of (i) a makeup flow including a third portion of the carrier gas to the flow splitter or (ii) an exhaust flow out of the flow splitter, wherein the pneumatic control module is configured to regulate the pressure within the flow splitter to thereby maintain the first split ratio at a substantially constant value.

A chromatography system includes a separation column that separates a sample carried by a compressible mobile phase flow into analytes and a splitter in fluidic communication with the separation column to receive and divide the compressible mobile phase flow into first and second mobile phase streams in accordance with a split ratio. A thermally modulated variable restrictor is coupled between the splitter and a detector. The restrictor receives the first mobile phase stream from the splitter and has a temperature element in thermal communication with the first mobile phase stream to exchange heat therewith. A controller, in communication with the restrictor, dynamically adjusts a temperature setting of the temperature element of the restrictor to adjust the heat exchange between the thermally modulated variable restrictor and the first mobile phase stream in order to keep the split ratio constant throughout a chromatographic run.

An analytical instrument assembly includes a gas chromatograph, a first detector, a second detector, and a pneumatic control module. The gas chromatograph includes a flow splitter configured to receive a sample. The first detector is coupled to the flow splitter. The second detector is coupled to the flow splitter. The pneumatic control module is coupled to the flow splitter and configured to deliver a carrier gas to the flow splitter. The flow splitter is configured to split the sample and deliver at least a first portion of the sample to the first detector and at least a second portion of the sample to the second detector at a first split ratio. The pneumatic control module is configured to deliver one of (i) a makeup flow including a third portion of the carrier gas to the flow splitter or (ii) an exhaust flow out of the flow splitter, wherein the pneumatic control module is configured to regulate the pressure within the flow splitter to thereby maintain the first split ratio at a substantially constant value.