G01N35/109

Medical analysis method

A medical analysis method uses a medical analysis machine provided with a poly-articulated robot (70) comprising joints defining at least six axes of rotation (A1, A2, A3, A4, A5, A6) and adapted for spacing and/or orienting a terminal member (66) according to six degrees of freedom, the terminal member bearing a grasping member (78) adapted for grasping a container (16). The medical analysis method comprises at least the succession of steps consisting of providing a container (16) containing a sample to be treated stemming from a human being or an animal, transferring said container (16) towards at least one treatment station of the medical analysis machine (100) by means of the poly-articulated robot, treating the sample in a treatment station, transferring the container towards a station for capturing images, and displaying the treatment results through a user interface.

Volume Data Representation and Processing for Liquid Dispensing Devices

A system and method for ejecting one or more fluids from a digital dispense device. The method includes a) inputting to a memory a volume per unit area for each of the one or more fluids to be ejected from the digital dispense device; b) matching the volume per unit area to a device resolution for the digital dispense device; c) formatting fluid ejectors for the digital dispense device for the device resolution; and d) ejecting fluid from the digital dispense device to provide the volume per area for each of the one or more fluids.

HIGH THROUGHPUT RADIOCHEMISTRY SYSTEM

A radiosynthesis system is disclosed that leverages droplet microfluidic radiosynthesis and its inherent advantages including reduction of reagent consumption and the ability to achieve high molar activity even when using low starting radioactivity. The radiosynthesis system enables the parallel synthesis of radiolabeled compounds using droplet-sized reaction volumes. In some embodiments, a single heater is used to create multiple reaction or synthesis sites. In other embodiments, separate heaters are used to create independently-controlled heating conditions at the multiple reaction or synthesis sites. In one embodiment, a four-heater setup was developed that utilizes a multi-reaction microfluidic chip and was assessed for the suitability with high-throughput radiosynthesis optimization. Replicates of several radiochemical operations including the full synthesis of various PET tracers revealed the platform to have high repeatability (e.g., consistent fluorination efficiency). The system may also be used for synthesis optimization.

FULLY-AUTOMATIC CHEMILUMINESCENCE IMMUNOASSAY ANALYZER

Disclosed is a fully-automatic chemiluminescence immunoassay analyzer, which comprises a base, a reaction cup conveyance module, a robot-arm sample injection module, an incubation module, a manipulator and transit module, a magnetic-separation cleaning module, and a detection module are mutually independently integrated on the base. The reaction cup conveyance module is used for conveying a reaction cup to a pre-determined position; the manipulator and transit module carries the reaction cup into the incubation module, to incubate the reaction cup for a constant-temperature reaction; the reaction cup in the incubation module is carried to the magnetic-separation cleaning module for magnetic-adsorption cleaning; and the reaction cup after cleaning is carried by the manipulator and transit module to the detection module for detection. A plurality of manipulators and a plurality of transit devices may be disposed as required, to link the mutually independent functional parts of the modules. Further, the instrument may be equipped with detection modules and process modules of various detection platforms, which cooperate with the manipulator and transit module to realize diverse detection in a table-top production line manner.

Automatic pipetting device for transferring samples and/or reagents and method for transferring liquid samples and/or reagents

Aspects of the present disclosure relate to methods and devices for automatically transferring samples and/or reagents from sample vessels and/or reagent vessels into at least one receiving vessel In one example embodiment, a pipetting device is disclosed including a pipettor that is movable along a first direction and has at least one first pipetting needle that is movable along an arm of the pipettor along a second direction, substantially normal to the first direction. The pipetting needle is lowerable along a third direction into the individual vessels. In some specific embodiments, the arm of the movable pipettor has at least one second pipetting needle which, regardless of the current position of the first pipetting needle, is movable past the first pipetting needle and is lowerable into the individual vessels.

Apparatus and methods for handling and spectrophotometry of small liquid samples

A method comprises: aspirating a sample through a needle capillary into a chamber having first and second windows, the capillary and chamber both affixed to a moveable robotic arm; causing a light beam generated by a light source that is affixed to the robotic arm to pass through the sample between the windows; detecting, using a photodetector that is affixed to the robotic arm, a quantity of the light that passes through the sample and the windows; determining an optical absorbance of the sample and a concentration of an analyte in the sample from the detected quantity of light; determining a quantity of the sample to dispense into an analytical apparatus based on the determined concentration; moving the robotic arm so as to cause the needle capillary to mate with an inlet port of an analytical apparatus; and dispensing the determined quantity of the sample into the analytical apparatus.

AUTOSAMPLER SYSTEM WITH DUAL ROTATIONAL AXIS UNCAPPING
20220390477 · 2022-12-08 ·

Systems and methods for automated cap removal with an autosampler system are described. In an aspect, an autosampler system includes, but is not limited to, a sample rack; a sample vessel stabilizer configured to transition the sample rack between a load/unload state and a lock state; an uncapper supported by a first z-axis support; and a sample probe supported by a second z-axis support, wherein the uncapper is configured to remove a cap from a sample vessel held by the sample rack when the sample rack is in the lock state, and wherein the uncapper is configured to change the position of the removed cap to permit access to an interior of the sample vessel by the sample probe without removing the sample vessel from the sample rack.

Automatic analysis apparatus and operating method therefor

An automatic analysis apparatus and an operating method for the automatic analysis apparatus. At least two magnetic separation units are introduced, each magnetic separation unit operating independently and being used for performing magnetic separation cleaning on a reaction solution in a reaction cup. Each magnetic separation unit may be used for any magnetic separation cleaning step in a one-step test project or a multi-step test project, thereby significantly increasing the test speed and the test throughput of the automatic analysis apparatus.

Systems and methods for pipette robots

Systems and methods applicable, for instance, to pipette robots. A pipette robot can perform one or more operations regarding deck calibration, one or more operations regarding pipette tip/probe calibration, one or more operations regarding pipette tip pick up, and/or one or more operations regarding tip ejection.

LIQUID HANDLING SYSTEM
20230053912 · 2023-02-23 ·

An automated liquid handling system includes a transfer robot unit, a handling module, and a fixing unit which is coupled to a head of the robot unit and on which a pipette assembly is to be mounted, wherein the handling module is provided with a mounting part detachably mounted on the fixing unit. The fixing unit includes a body part, a fixing part hook formed at an upper portion of one side of the body part and a lower protrusion disposed at a lower portion of the one side of the body part, the mounting part includes a body, a movable hook part formed at an upper portion of one side of the body and a lower groove formed at a lower portion of the one side of the body to correspond to the lower protrusion, a catching step is formed at the lower groove, and the lower protrusion extends from the lower portion of the one side of the body part to support the catching step from below, and the movable hook part is hook-coupled to a fixing unit hook.