Patent classifications
G01R33/4625
Magnetic resonance spectroscopy pulse sequence, acquisition, and processing system and method
Systems and methods are provided for processing a set of multiple serially acquired magnetic resonance spectroscopy (MRS) free induction decay (FID) frames from a multi-frame MRS acquisition series from a region of interest (ROI) in a subject, and for providing a post-processed MRS spectrum. Processing parameters are dynamically varied while measuring results to determine the optimal post-processed results. Spectral regions opposite water from chemical regions of interest are evaluated and used in at least one processing operation. Frequency shift error is estimated via spectral correlation between free induction decay (FID) frames and a reference spectrum. Multiple groups of FID frames within the acquired set are identified to different phases corresponding with a phase step cycle of the acquisition. Baseline correction is also performed via rank order filter (ROF) estimate and a polynomial fit. Sections of the ROF may be excluded from the polynomial fit, such as for example sections determined to be associated with relevant spectral peaks.
MAGNETIC RESONANCE SPECTROSCOPY PULSE SEQUENCE, ACQUISITION, AND PROCESSING SYSTEM AND METHOD
Systems and methods are provided for processing a set of multiple serially acquired magnetic resonance spectroscopy (MRS) free induction decay (FID) frames from a multi-frame MRS acquisition series from a region of interest (ROI) in a subject, and for providing a post-processed MRS spectrum. Processing parameters are dynamically varied while measuring results to determine the optimal post-processed results. Spectral regions opposite water from chemical regions of interest are evaluated and used in at least one processing operation. Frequency shift error is estimated via spectral correlation between free induction decay (FID) frames and a reference spectrum. Multiple groups of FID frames within the acquired set are identified to different phases corresponding with a phase step cycle of the acquisition. Baseline correction is also performed via rank order filter (ROF) estimate and a polynomial fit. Sections of the ROF may be excluded from the polynomial fit, such as for example sections determined to be associated with relevant spectral peaks.
Method for measuring the gradient field of a nuclear magnetic resonance (NMR) system based on the diffusion effect
A method for measuring a gradient field of a nuclear magnetic resonance (NMR) system based on a diffusion effect uses a non-uniform field magnet, an NMR spectrometer, a radio frequency (RF) power amplifier, an RF coil, and a standard quantitative phantom with known apparent diffusion coefficient (ADC) and time constant for decay of transverse magnetization after RF-pulse (T2). A plurality of sets of signals are acquired by an NMR sequence with different diffusion-sensitive gradient durations or different echo spacings and the magnitude of the gradient field is calculated by fitting based on the plurality of sets of signals. The method does not require an additional dedicated magnetic field detection device, has a short measurement time, is easy to use with the NMR system, and is convenient to complete gradient field measurement at the installation site, thereby improving the installation and service efficiency of the NMR system.
NMR magnet system with Stirling cooler
An NMR magnet system uses a Stirling cooler having a cold head that extends into a housing of the system to cool a cold shield surrounding a cryogen vessel. The system may have a damper located between the cooler and the cold shield to reduce a transmission of vibration from the cooler to a magnet coil immersed in the cryogen. The damper may be passive, or may be part of an active damping system that uses an acceleration sensor to drive an active damper that compensates for cooler vibration. A compensation apparatus may use a stored characteristic of a signal distortion caused by the vibration and, in response to a trigger signal from the cooler, apply compensation to an excitation signal provided to a sample by an NMR probe in a bore of the magnet coil, or to an FID signal from the sample that is detected by the probe.
NUCLEAR MAGNETIC RESONANCE SYSTEM-BASED SUBSTANCE MEASUREMENT METHOD AND SYSTEM
A nuclear magnetic resonance (NMR) system-based substance measurement method, including: acquiring several echo signals of an NMR pulse sequence varying in echo spacing from a substance to be measured followed by processing to obtain several signals varying in transverse relaxation and diffusion attenuation; and fitting, in combination with the prior knowledge, the signals to obtain the diffusion coefficient, transverse relaxation time or/and content weight of individual components of the substance to be measured. This application further provides a substance measurement system including a console, a magnet module, and an NMR system.
RAPID MEASUREMENT OF HYDROCARBON CORROSION PROPENSITY
A process for producing liquid transportation fuels in a petroleum refinery while preventing or minimizing corrosion of refinery process equipment. Spectral data selected from mid-infrared spectrometry, nuclear magnetic resonance spectrometry, or both is obtained and converted to wavelets coefficients data. A pattern recognition genetic algorithm is then trained to recognize subtle features in the wavelet coefficients data to allow classification of crude samples into one of two groups based on corrosion propensity. One of several actions is taken depending upon the measured corrosion propensity of the potential feed stock in order to prevent or minimize corrosion while producing one or more liquid hydrocarbon fuels.
PROCESSING 1H-NMR SPECTRAL DATA
A computer-implemented method of processing .sup.1H-NMR spectral data is disclosed. The method comprises receiving .sup.1H-NMR spectral data for a sample or set of samples, performing a Fourier transform of the .sup.1H-NMR spectral data to obtain Fourier-transformed spectral data, first differentiating the imaginary part of the Fourier-transformed spectral data or processed Fourier-transformed spectral data obtained from the Fourier-transformed spectral data to obtain a first derivative and storing the first derivative in storage.
METHOD FOR ACQUIRING NMR PHASE-SENSITIVE 2D J-RESOLVED SPECTRUM BY SUPPRESSING STRONG COUPLING SPURIOUS PEAKS
A method for acquiring nuclear magnetic resonance (NMR) phase-sensitive two-dimensional (2D) J-resolved spectrum by suppressing strong coupling spurious peaks, comprising: 1) placing a sample, collecting a conventional one-dimensional (1D) spectrum of the sample, and measuring a time width (pw) of a 90° pulse, wherein the conventional 1D spectrum provides J coupling information and chemical shift information of the sample; and 2) introducing a pulse sequence for suppressing strong coupling, setting parameters of a chirp sweep frequency pulse, a pure shift yielded by chirp excitation (PSYCHE) module, and a J sampling module, and collecting and saving data of a spectrum.
Method for acquiring NMR phase-sensitive 2D J-resolved spectrum by suppressing strong coupling spurious peaks
A method for acquiring nuclear magnetic resonance (NMR) phase-sensitive two-dimensional (2D) J-resolved spectrum by suppressing strong coupling spurious peaks, comprising: 1) placing a sample, collecting a conventional one-dimensional (1D) spectrum of the sample, and measuring a time width (pw) of a 90° pulse, wherein the conventional 1D spectrum provides J coupling information and chemical shift information of the sample; and 2) introducing a pulse sequence for suppressing strong coupling, setting parameters of a chirp sweep frequency pulse, a pure shift yielded by chirp excitation (PSYCHE) module, and a J sampling module, and collecting and saving data of a spectrum.
Magnetic resonance imaging apparatus
There is provided a technique for obtaining temperature information for inside of a living body and accuracy information thereof in short time with low burden imposed on a subject. It is realized with a spectrum calculator configured to perform MRS or MRSI measurement for two kinds of substances showing difference of resonant frequencies and calculating spectra of magnetic resonance signals of the two kinds of substances, a temperature information calculator configured to calculate temperature information for inside of the subject on the basis of peaks of the calculated spectra, a temperature accuracy information calculator configured to calculate temperature accuracy information indicating accuracy of the temperature information on the basis of peaks of the calculated spectra, and a display information generator configured to generate display information to be displayed on a display device on the basis of the temperature information and the temperature accuracy information.