An NMR spectrum is acquired from a nucleus of interest in a solvent included in a sample solution. A spectrum analyzer analyzes a number of splits, a splitting interval, a number of signals, and a signal interval based on the NMR spectrum. Based on these characteristic quantities, an identifier identifies the solvent. In another configuration, a plurality of NMR spectra acquired from a plurality of nuclei of interest included in the solvent may be analyzed.

Embodiments of a compact portable nuclear magnetic resonance (NMR) device are described which generally include a housing that provides a magnetic shield; an axisymmetric permanent magnet assembly in the housing and having a bore, a plurality of magnetic elements that together provide a well confined axisymmetric magnetization for generating a near-homogenous magnetic dipole field B.sub.0 directed along a longitudinal axis and providing a sample cavity for receiving a sample, and high magnetic permeability soft steel poles to improve field uniformity: a shimming assembly with coils disposed at the longitudinal axis for spatially correcting the near homogenous magnetic field B.sub.0; and a spectrometer having a control unit for measuring a metabolite in the sample by applying magnetic stimulus pulses to the sample, measuring free induction delay signals generated by an ensemble of hydrogen protons within the sample; and suppressing a water signal by using a dephasing gradient with frequency selective suppression.

Apparatus for the measurement of ore in mine haul vehicles is disclosed, the apparatus comprising: a portal, defining a portal zone, wherein a haul vehicle carrying ore is positionable in or movable through the portal zone; and at least one magnetic resonance (MR) sensor comprised in the portal. The MR sensor includes a main loop and a drive loop located above the main loop. A magnetic resonance sensor control system is provided and configured to control at least one of: the positioning of the at least one MR sensor relative to the portal zone and/or ore burden; the positioning of elements comprised in the MR sensor relative to each other; electromagnetic suppression characteristics of the at least one MR sensor; and/or sensitivity of the at least one MR sensor as a function of distance of the sensor from the ore burden.

A system and a method for applying .sup.13C or .sup.1H NMR spectroscopy to a sample of oil in order to calculate and assign an indicative property such as cetane number, pour point, cloud point, aniline point and/or octane number of a gas oil or naphtha fraction of the crude oil.

Disclosed is a method for determining fibre porosity in a fibre suspension. A sample is taken from a fibre suspension and fibre porosity determination is performed by determining the ratio of fibre-internal water to fibre-external bound water as an online measurement using a NMR spectroscope in successive steps of: generating a magnetic field for exciting protons of water contained in the sample; exciting water molecules of fibre suspension contained in the sample with a frequency pulse provided by a coil; measuring a return signal of the frequency pulse that returns from water molecules to the coil; determining the proton relaxation time and the amplitude of the return signal from the return signal; and determining fibre porosity of the fibre suspension based on the amplitude and the relaxation time of the exponential return signal. Also disclosed is a device for determining fibre porosity of a fibre suspension and a control system connected to a fibre web machine.

A spectrum y includes a waveform-of-interest component and a baseline component serving as a wide-band component. An optimum solution of a signal model x is determined according to a first condition to fit a corresponding portion S.sub.IFx of a baseline model Fx with respect to a representative portion y.sub.I of the baseline component, and a second condition to minimize an Lp norm (wherein p≤1) of the signal model x. An estimated baseline component determined from the optimum solution of the signal model x is subtracted from the spectrum y.

Biomarkers and/or risk assessments identify patients having an increased risk of certain clinical disease states including, for example, CHD, type 2 diabetes, dementia, or all-cause death (ACD) using NMR signal to measure a level of “GlycA” in arbitrary units or in defined units (e.g., μmol/L) that can be determined using a defined single peak region of proton NMR spectra. The GlycA measurement can be used as an inflammation biomarker for clinical disease states. The NMR signal for GlycA can include a fitting region of signal between about 2.080 ppm and 1.845 ppm of the proton NMR spectra.

The present invention generally pertains to methods of characterizing antibody higher order structure. In particular, the present invention pertains to the use of novel NMR methods to compare manufacturing process variability in antibody higher order structure.

This invention provides, among other things, methods for determining the average number of first polymers covalently attached to protein-first polymer conjugates in a solution.

According to one embodiment, a reconstruction apparatus obtains acquired raw data, and reconstruct a data set that represents a measured physical amount with a multidimensional space based on the acquired raw data. Herein, the apparatus performs reduction processing for generating noise-reduced partial data from partial data relating to a partial area of a data set at a current number of iterations, error compensation processing for compensating errors in a data set at the current number of iterations with respect to the acquired raw data, and optimization processing for reconstructing the data set by repeating the reduction processing and the error compensation processing until predetermined criteria are met, while moving the partial area.