One or more techniques and/or systems are disclosed for effectively illuminating a target. The target may be in a confined field of view area. Such systems may mitigate shadows and lack of light homogeneity at surgical procedure settings, research sites, or other localized areas where humans may operate in a confined field of view area. One or more lighting modules can be disposed in a target area, for illumination of one or more illumination target locations in the confined field of view. An object detection component can detect an object or desired target in the target field of view location, and provide data indicative of the detected object/target to an illumination module adjustment component. Based on the data indicative of the detected object/target, the illumination module adjustment component can provide data indicative of an illumination adjustment to the first illumination module to provide desired illumination.

An optical imaging system for imaging a target during a medical procedure, the imaging system involving an optical assembly having moveable zoom optics and moveable focus optics, a zoom actuator and a focus actuator for positioning the zoom and focus optics, respectively, a controller for controlling the zoom and focus actuators independently in response to received control input, a camera for capturing an image of the target from the optical assembly, the system capable of performing autofocus during a medical procedure.

An analysis and observation device includes: an electromagnetic wave emitter that emits a primary electromagnetic wave; a reflective object lens having a primary mirror provided with a primary reflection surface reflecting a secondary electromagnetic wave and a secondary mirror provided with a secondary reflection surface receiving and further reflecting the secondary electromagnetic wave; first and second detectors that receive the secondary electromagnetic wave and generate an intensity distribution spectrum; and a controller that performs component analysis of a sample based on the intensity distribution spectrum. A transmissive region through which the primary electromagnetic wave is transmitted is provided at a center of the secondary mirror. The transmissive region transmits the primary electromagnetic wave, which has been emitted from the electromagnetic wave emitter and passed through an opening of the primary mirror, thereby emitting the primary electromagnetic wave along an analysis optical axis of the reflective object lens.

The disclosed technology relates to an inspection apparatus that includes a stage configured to retain a specimen for inspection, an imaging device having a field of view encompassing at least a portion of the stage to view a specimen retained on the stage, and a plurality of lights disposed on a moveable platform. The inspection apparatus can further include a control module coupled to the imaging device, each of the lights and the moveable platform. The control module is configured to perform operations including: receiving image data from the imaging device, where the image data indicates an illumination landscape of light incident on the specimen; and automatically modifying, based on the image data, an elevation of the moveable platform or an intensity of one or more of the lights to adjust the illumination landscape. Methods and machine-readable media are also contemplated.

An adjustable light source device for a stereoscopic surgical microscope has a circuit board and multiple light sources. The circuit board is mounted in an outer casing of the stereoscopic surgical microscope and is electrically connected to a host computer of the stereoscopic surgical microscope. The light sources are electrically mounted on the circuit board at spaced intervals around two objective lenses of the stereoscopic surgical microscope and extend out of the outer casing. Each one of the light sources has a wavelength different from wavelengths of the other light sources and is controlled to emit light by an operating set of the stereoscopic surgical microscope via a program processing interface of the host computer sending signals to the circuit board. The adjustable light source device can emit lights with different wavelengths to enable the stereoscopic surgical microscope to capture clearer images for various surgical divisions.

The present disclosure provides an imaging system, including methods and apparatus, with oblique illumination. In an exemplary method of imaging, a sample may be illuminated obliquely with excitation light generated by only a subset of a plurality of light sources mounted to an annular frame. An image may be detected, with the image formed with photoluminescence induced in the sample by the excitation light and received from a central opening of the annular frame.

An imaging sensing system containing: i) a fibre optic plate (FOP) having a proximal end, a distal end and a body situated between the proximal and distal ends; ii) at least one illumination component, and ii) an image sensor proximate the FOP.

An optical measurement system includes an optical sensor assembly for measuring an object located beneath the optical sensor assembly. A deployment mechanism is pivotally connected relative to the optical sensor assembly that moves a secondary measurement aid, such as a touch sensor, between a deployed position and a retracted position. When in the retracted position, the secondary measurement aid does not inhibit movement of the optical sensor with respect to the object being measured.

Humidified sample preparation station for serial crystallography according to one embodiment is a humidified enclosure that delivers relative humidities above 95% and preferably above 97% in standard operation, and that can allow microscope observation of samples within. Humidified sample preparation station for serial crystallography can be used for preparation of protein crystal samples for examination using X-rays and for protein structure determination by X-ray crystallography, involving addition of liquid to the sample and removal of liquid from the sample using vacuum or suction.

A lens device for an illumination assembly, wherein the lens device comprises at least one ring region, wherein each ring region extends along a circumferential direction about a central axis of the lens device, wherein each ring region comprises a plurality of segments, wherein each segment forms a circular arc portion of a respective ring region and wherein each segment comprises a first end in the circumferential direction and a second end opposite to the first end in the circumferential direction, wherein each segment has a first refractive index at a reference wavelength at the first end at a first radial distance from the central axis and a second refractive index at the reference wavelength at the second end at the first radial distance, said second refractive index differing from the first refractive index. An illumination assembly, a coordinate measuring machine and a method are also disclosed.