The present invention relates, in general terms, to X-ray detecting films and uses thereof. The present invention also relates to methods of fabricating the X-ray detecting films. In particular, the X-ray detecting film comprises persistent luminescent nanoparticles dispersed within a flexible polymer matrix, wherein the persistent luminescent nanoparticles are dispersed in the flexible polymer matrix at a concentration of about 0.1% to about 100%.

A method of creating an image including retrieving three-dimensional image data of an anatomy, retrieving a model of a portion of the anatomy, associating the model with the three-dimensional image data such that the model defines a bounded volume within the three-dimensional image data corresponding to the portion of the anatomy, and creating a virtual radiograph of the portion of the anatomy. Creating the virtual radiograph includes casting a plurality of rays from an origin point through the bounded volume, sampling, for each ray, the bounded volume at a plurality of sampling steps along the ray, the sampling steps separated by a sampling distance, and calculating, for each ray, an accumulated attenuation value of the bounded volume along the ray based on the samples.

A method of creating an image including retrieving three-dimensional image data of an anatomy, retrieving a model of a portion of the anatomy, associating the model with the three-dimensional image data such that the model defines a bounded volume within the three-dimensional image data corresponding to the portion of the anatomy, and creating a virtual radiograph of the portion of the anatomy. Creating the virtual radiograph includes casting a plurality of rays from an origin point through the bounded volume, sampling, for each ray, the bounded volume at a plurality of sampling steps along the ray, the sampling steps separated by a sampling distance, and calculating, for each ray, an accumulated attenuation value of the bounded volume along the ray based on the samples.

A method for generating a virtual radiograph for display on a display device, including providing an image generation system having a processing circuit including a processor and a memory device, the image generation system coupled to the display device. The method further including retrieving three-dimensional image data of an anatomy stored in the memory and retrieving a three-dimensional bone model corresponding to a portion of the anatomy stored in the memory. The method further including associating the three-dimensional bone model with the three-dimensional image data such that the three-dimensional bone model defines first boundary containing a first bounded volume within the three-dimensional image data corresponding to the portion of the anatomy, and performing a volume ray casting process on the three-dimensional image data.