Provided are computer-implemented methods and systems for generating and/or utilizing data analysis algorithm(s) for predicting and/or detecting a clinical condition related to insertion of a medical instrument toward a target in a body of a patient based, inter alia, on data related to an automated medical device and/or to operation thereof.

An electro-optic observation device, in particular a thermal imaging device, is provided. The electro-optic observation device includes a handheld device housing, a lens group arranged in the device housing on the entrance side, an image capture unit arranged in the device housing on the image side with respect to the lens group, an image display unit arranged in the device housing, an eyepiece arranged on the exit side with respect to the image display unit, and also a control device configured to control at least the image display unit depending on user-specifically variable parameters. In addition, the electro-optic observation device includes, as input means for varying the parameters, a rotary wheel accessible on the device housing for access by a user.

A neuroimaging-based approach to predict treatment response in mental disorders by acquiring and analysing brain PET dopamine measures from patients. The method uses a short, simplified protocol for [18F]FDOPA brain PET imaging adapted for clinical practice. Individual [18F]FDOPA brain PET data are then quantified with a fully-automated analysis pipeline to extract information on the dopamine function of the subject. This information coupled with clinical information is run through a prediction algorithm to identify those patients whose illness will not respond to conventional antipsychotics.

A system for tracking an instrument during a procedure on a patient is provided. The system includes a rotatable gantry, an x-ray imaging device, a processor, and a memory coupled to the processor. The processor is configured to: generate a three dimensional (3D) image based on a plurality of initial x-ray projections taken at a plurality of projection angles; generate an annotated 3D image of the 3D image including annotations of the target location and at least one planned instrument path on the 3D image; generate a plurality of two dimensional (2D) annotations based on the annotated 3D image at each projection angle; superimpose each 2D annotation onto the initial x-ray projection of the corresponding projection angle; obtain a plurality of subsequent x-ray projections of the patient at the plurality of projection angles; and co-register each subsequent x-ray projection with a corresponding annotated initial x-ray projection for each projection angle.

An interaction method for an electronic device for skin detection includes recognizing a hand action and a face of a user to determine a target hand action; determining a detection target corresponding to the hand action based on the target hand action; determining from an extended content library based on the detection target and a shape of the detection target, extended content associated with the detection target and the shape of the detection target, and outputting the extended content.

Arthroscopes and laparoscopes are available in several lens cuts to cover different clinical situations of interest, with the surgeon having to exchange the optics in order to change the direction of view of the camera. The presently disclosed embodiments disclose real-time image processing systems and methods that enable the user to arbitrarily change the direction of view of a surgical camera with the advantage of avoiding the disruption in workflow caused by the physical exchange of the optics. In addition, the presently disclosed embodiments disclose performing zoom along an arbitrary viewing direction (directional zoom) that enables to increase the scale of a region of interest without decreasing the overall field-of-view or losing image contents.

The present invention provides a method, system and device for reflectional glare reduction in endoscope images. The reflective glare refers to clusters of congruent bright and often saturated image pixels caused by heterogenous surfaces of a tissue anatomy reflecting the illumination from a light source, which could be as annoying as distractive. Under automatic exposure control, in a scene of overexposure due to a reflection glare, the brightness of the glare is significantly higher than that of background image of tissue anatomy, and there is usually a gap between the two. Through mapping the pixel depth of the glare into the gap, the contrast between the glare and the background image is reduced, which improves the user experience of the endoscopy.

The invention relates to a method for determining a registration error of a structure on a mask for semiconductor lithography, comprising the following method steps: generating an image of at least one region of the mask, determining at least one measuring contour in the image, and matching the forms of a design contour and a measuring contour to one another while at the same time matching the registration of the two contours.

A method and apparatus for tracking disease progression as revealed by multiple lesions perform a global optimization to identify corresponding lesions by overlap, for example, after outlines of the lesions have been morphologically dilated. A clustering algorithm addresses the problem of lesions separating into parts or joining together to provide a clear picture of disease progression.

A medical image analysis system includes an image receiving/storing unit to receive/store digital images from a slide scanner; an image analysis unit to perform automatic analysis related to tumor cell detection, biomarker quantification and/or pattern recognition, and return analyzed images and/or analysis results; an image evaluation unit with an operation platform and user interface for review of images/analyzed images; an assembly/unification unit having a first interface to the analysis unit, the assembly/unification unit transfering the images to the analysis unit and receiving analyzed images and/or analysis results; a second interface to the evaluation unit, the assembly/unification unit transfering the images/analyzed images and receiving evaluations; a picture archiving/communication system or vendor neutral archive interface, the assembly/unification unit assembling and exporting the images/analyzed images/evaluations to the archiving/communication system or neutral archive.