Systems and computer-implemented methods of performing image registration. One method includes receiving a first image and a second image acquired from a patient at different times and, in each of the first image and the second image, detecting an upper boundary of an imaged object in an image coordinate system and detecting a lower boundary of the imaged object in the image coordinate system. The method further includes, based on the upper boundary and the lower boundary of each of the first image and the second image, cropping and padding at least one of the first image and the second image to create an aligned first image and an aligned second image and executing a registration model on the aligned first image and the aligned second image to compute a deformation field between the aligned first image and the aligned second image.

Various methods and systems are provided for computed tomography imaging. In one embodiment, a method includes acquiring, with an x-ray detector and an x-ray source coupled to a gantry, a three-dimensional image volume of a subject while the subject moves through a bore of the gantry and the gantry rotates the x-ray detector and the x-ray source around the subject, inputting the three-dimensional image volume to a trained deep neural network to generate a corrected three-dimensional image volume with a reduction in aliasing artifacts present in the three-dimensional image volume, and outputting the corrected three-dimensional image volume. In this way, aliasing artifacts caused by sub-sampling may be removed from computed tomography images while preserving details, texture, and sharpness in the computed tomography images.

A method for performing a procedure on a patient includes acquiring a three-dimensional image of a location of interest on the patient and a two-dimensional image of the location of interest can be acquired. A computer system can relate the three-dimensional image with the two-dimensional image to form a holographic image dataset. The computer system can register the holographic image dataset with the patient. The augmented reality system can render a hologram based on the holographic image dataset from the patient. The hologram can include a projection of the three-dimensional image and a projection of the two-dimensional image. The practitioner can view the hologram with the augmented reality system and perform the procedure on the patient. The practitioner can employ the augmented reality system to visualize a point on the projection of the three-dimensional image and a corresponding point on the projection of the two-dimensional image during the procedure.

A computer device obtains a medical image set. The device identifies a difference between the reference medical image and the target medical image to obtain a candidate non-lesion region in the target medical image. The device determines area size information of the candidate non-lesion region as candidate area size information. The device adjusts the candidate non-lesion region according to the annotated area size information when the candidate area size information does not match the annotated area size information, so as to obtain a target non-lesion region in the target medical image.

A method and system for mapping boundary detecting features of at least one source triangulated mesh of known topology to a target triangulated mesh of arbitrary topology. A region of interest in a volumetric image associated with each triangle of the target triangulated mesh is provided to a feature mapping network. The feature mapping network assigns a feature selection vector to each triangle of the target triangulated mesh. The associated region of interest and assigned feature selection vector for each triangle of the target triangulated mesh are provided to a boundary detection network. A predicted boundary based on features of the associated region of interest selected by the assigned feature selection vector is obtained from the boundary detection network.

The present invention relates to a method of processing CT data for suppressing image cone beam artefacts (CBA) in CT images, which are reconstructed from said CT data. For the reconstruction the Frequency Split method is used. However, a straightforward use of this method can lead to an un-desired increase of the residual low-frequency noise left in the basis image after applying image domain de-noising methods. This residual noise then propagates rather linearly to the spectral results. In order to avoid this increase of the noise, the method presented here uses the FS method selectively and yet effectively. Thus, in a first aspect of the invention there is provided a method of processing computer tomography (CT) data for suppressing image cone beam artefacts (CBA) in CT images to be reconstructed from said CT data. The method comprises the steps of obtaining CT data generated during a CT scan of a patient (step S1); decomposing the obtained CT data in the projection domain resulting in a plurality of decomposed sinograms (step S2); and non-uniformly spreading between said decomposed sinograms noise and/or inconsistencies that would lead to image cone beam artefacts (step S3).

Systems and methods of PET attenuation correction using low-field MR image data includes receiving a first set of image data and a set of low-field magnetic resonance (MR) image data. An attenuation correction map is generated from the low-field MR image data using a first trained neural network. At least one attenuation correction process is applied to the first set of image data based on the attenuation correction map to generate at least one clinical attenuation-corrected image.

In a gantry for a computed tomography device, a rotary frame is arranged on the tilt frame so that the rotary frame rotates relative to the tilt frame about an axis of rotation. The tilt frame is arranged on the support frame so that the tilt frame tilts about a tilt axis relative to the support frame, such that a tilt angle of the tilt frame relative to the support frame is changeable by a tilting movement of the tilt frame relative to the support frame about the tilt axis. The proximity switch has a proximity sensor and a reference mark, which interacts with the proximity sensor. The proximity switch is also coupled to the support frame and to the tilt frame such that the proximity switch is configured to react to an approach of the tilt angle to a reference angle.

A registration chaining system provides information transfer along a chain of registrations of images of same or different modalities. A registration at each link is based on a shared feature readily distinguished in a pair of images. The information is transferred using the registration.

A method includes applying both a first dedicated functional-anatomical registration scheme to a first volume of interest to deform the first volume of interest and a second dedicated functional-anatomical registration scheme to a second volume of interest to deform the second volume of interest, wherein the first volume of interest at least partially encompasses the second volume of interest. The method includes identifying or segmenting relevant organs or anatomical structures related to a first group and a second group in the first volume of interest and the second volume of interest, respectively; generating a spatially smooth-transition weight mask that gives higher weight to image data corresponding to the identified or segmented relevant organs or anatomical structures related to the first group and the second group; and generating a final cohesive registered image volume from the first image volume and the second image volume utilizing the spatially smooth-transition weight mask.