Systems and computer-implemented methods of performing image registration. One method includes receiving a first image and a second image acquired from a patient at different times and, in each of the first image and the second image, detecting an upper boundary of an imaged object in an image coordinate system and detecting a lower boundary of the imaged object in the image coordinate system. The method further includes, based on the upper boundary and the lower boundary of each of the first image and the second image, cropping and padding at least one of the first image and the second image to create an aligned first image and an aligned second image and executing a registration model on the aligned first image and the aligned second image to compute a deformation field between the aligned first image and the aligned second image.

A computer device obtains a medical image set. The device identifies a difference between the reference medical image and the target medical image to obtain a candidate non-lesion region in the target medical image. The device determines area size information of the candidate non-lesion region as candidate area size information. The device adjusts the candidate non-lesion region according to the annotated area size information when the candidate area size information does not match the annotated area size information, so as to obtain a target non-lesion region in the target medical image.

A method and system for mapping boundary detecting features of at least one source triangulated mesh of known topology to a target triangulated mesh of arbitrary topology. A region of interest in a volumetric image associated with each triangle of the target triangulated mesh is provided to a feature mapping network. The feature mapping network assigns a feature selection vector to each triangle of the target triangulated mesh. The associated region of interest and assigned feature selection vector for each triangle of the target triangulated mesh are provided to a boundary detection network. A predicted boundary based on features of the associated region of interest selected by the assigned feature selection vector is obtained from the boundary detection network.

Systems and methods of PET attenuation correction using low-field MR image data includes receiving a first set of image data and a set of low-field magnetic resonance (MR) image data. An attenuation correction map is generated from the low-field MR image data using a first trained neural network. At least one attenuation correction process is applied to the first set of image data based on the attenuation correction map to generate at least one clinical attenuation-corrected image.

A method of analyzing thoracic insufficiency syndrome (TIS) in a subject by performing quantitative dynamic magnetic resonance imaging (QdMRI) analysis. The QdMRI analysis includes performing four-dimensional (4D) image construction of a TIS subject's thoracic cavity. The 4D image includes a sequence of two dimensional (2D) images of the TIS subject's thoracic cavity over a respiratory cycle of the TIS subject. The QdMRI analysis also includes segmenting a region of interest (ROI) within the 4D image, determining TIS measurements within the ROI, comparing the TIS measurements to normal measurements determined from ROIs in 4D images of the thoracic cavities of normal subjects that are not afflicted by TIS, and outputting quantitative markers indicating deviation of the thoracic cavity of the TIS subject relative to the thoracic cavities of the normal subjects.

A registration chaining system provides information transfer along a chain of registrations of images of same or different modalities. A registration at each link is based on a shared feature readily distinguished in a pair of images. The information is transferred using the registration.

A method includes applying both a first dedicated functional-anatomical registration scheme to a first volume of interest to deform the first volume of interest and a second dedicated functional-anatomical registration scheme to a second volume of interest to deform the second volume of interest, wherein the first volume of interest at least partially encompasses the second volume of interest. The method includes identifying or segmenting relevant organs or anatomical structures related to a first group and a second group in the first volume of interest and the second volume of interest, respectively; generating a spatially smooth-transition weight mask that gives higher weight to image data corresponding to the identified or segmented relevant organs or anatomical structures related to the first group and the second group; and generating a final cohesive registered image volume from the first image volume and the second image volume utilizing the spatially smooth-transition weight mask.

Techniques are described for enhancing the quality of three-dimensional (3D) anatomy scan images using deep learning. According to an embodiment, a system is provided that comprises a memory that stores computer executable components, and a processor that executes the computer executable components stored in the memory. The computer executable components comprise a reception component that receives a scan image generated from 3D scan data relative to a first axis of a 3D volume, and an enhancement component that applies an enhancement model to the scan image to generate an enhanced scan image having a higher resolution relative to the scan image. The enhancement model comprises a deep learning neural network model trained on training image pairs respectively comprising a low-resolution scan image and a corresponding high-resolution scan image respectively generated relative to a second axis of the 3D volume.

A computer apparatus and methods generate multi-parametric color composite images from multi-echo chemical shift encoded (CSE) MRI. Some embodiments use inherently co-registered images (i.e., image maps) that are combined into a single intuitive composite color image. The color (e.g., brightness, hue, and/or saturation) reflects in part the water and fat content, and other properties, particularly T2* relaxation (related to magnetic susceptibility) of the tissue.

The invention provides for a magnetic resonance imaging system (100) for acquiring magnetic resonance data (142) from a subject (118) within a measurement zone (108). The magnetic resonance imaging system (100) comprises: a processor (130) for controlling the magnetic resonance imaging system (100) and a memory (136) storing machine executable instructions (150, 152, 154), pulse sequence commands (140) and a dictionary (144). The pulse sequence commands (140) are configured for controlling the magnetic resonance imaging system (100) to acquire the magnetic resonance data (142) of multiple steady state free precession (SSFP) states per repetition time. The pulse sequence commands (140) are further configured for controlling the magnetic resonance imaging system (100) to acquire the magnetic resonance data (142) of the multiple steady state free precession (SSFP) states according to a magnetic resonance fingerprinting protocol. The dictionary (144) comprises a plurality of tissue parameter sets. Each tissue parameter set is assigned with signal evolution data pre-calculated for multiple SSFP states.