A detection circuit includes a first pulse sequence generator configured to generate a first pulse sequence based on a first signal and a second pulse sequence generator configured to generate a second pulse sequence based on a second signal. Amplitudes and frequencies of the first signal and the second signal are different. The detection circuit further includes a first conductance device configured to receive the first pulse sequence to generate a first conductance, a second conductance device configured to receive the second pulse sequence to generate a second conductance, and a difference detection circuit configured to, when both the first conductance device and the second conductance device receive a third signal, output a voltage representing a difference between the first conductance and the second conductance. The detection circuit can be applied to an image edge detection scenario.

A detection circuit includes a first pulse sequence generator configured to generate a first pulse sequence based on a first signal and a second pulse sequence generator configured to generate a second pulse sequence based on a second signal. Amplitudes and frequencies of the first signal and the second signal are different. The detection circuit further includes a first conductance device configured to receive the first pulse sequence to generate a first conductance, a second conductance device configured to receive the second pulse sequence to generate a second conductance, and a difference detection circuit configured to, when both the first conductance device and the second conductance device receive a third signal, output a voltage representing a difference between the first conductance and the second conductance. The detection circuit can be applied to an image edge detection scenario.

The present disclosure provides systems and methods for an output architecture for an implantable pulse generator of a neurostimulation system. The output architecture includes a power supply, a plurality of outputs, a global source current regulator coupled to the power supply and operable to source current from the power supply to the plurality of outputs through a plurality of source current branches, a global sink current regulator operable to sink current from the plurality of outputs to ground through a plurality of sink current branches, a current source branch selector operable to select, for each of the plurality of outputs, an amount of current sourced from the plurality of source current branches, and a current sink branch selector operable to select, for each of the plurality of outputs, an amount of current sunk to the plurality of sink current branches.

Described herein are apparatuses and methods for applying high voltage, high current, sub-microsecond (e.g., nanosecond range) pulsed output to a biological material, e.g., tissues, cells, etc., while preventing damage from load arcing. Some of the apparatuses and methods described herein may limit the load and pulsed power source current in case of load arcing significantly by using a transmission line (e.g., coaxial cable, twisted pair or parallel pair cables) between the pulsed power source and the load having a length configured to achieve this goal.

A high-power pulse generator (1), belonging to the LTD family, includes two series of power modules, one series of standard modules (3s) and one series of modified modules (3m), each including a switch (6s; 6m), provided with a trigger electrode (9s; 9m), positioned in series between two capacitors (4s; 4m), the modified modules being designed to produce a pulse at a frequency substantially three times the frequency of the standard modules, and a trigger device (13) designed to control the standard and modified switches (6s; 6m) via a single trigger signal applied to the trigger electrode (9s; 9m) of same. The trigger signal is applied to the switches through a trigger impedance (10m; 10s) that is different between the standard and modified modules, and the plateau slope of the generated pulse depends on the difference between the value of the standard impedance and that of the modified impedance.

The present invention provides a high voltage pulse modulating power source based on alternate group triggering, which comprises: a DC stabilized voltage source for supplying power to the high voltage pulse modulating power source; a plurality of solid-state switches; a plurality of triggers corresponding to said plurality of solid-state switches, wherein each trigger provides a trigger signal to its corresponding solid-state switch to turn on said corresponding solid-state switch, wherein said plurality of triggers are divided into at least two groups of triggers; a time sequence control module, which, at time t1, controls said plurality of triggers to generate trigger signals so as to turn on said plurality of solid-state switches simultaneously, and at time t2, controls one group of said at least two groups of triggers to generate trigger signals to turn on solid-state switches corresponding to this group of triggers, wherein time t1 and time t2 appear alternately.

The present invention provides a high voltage pulse modulating power source based on alternate group triggering, which comprises: a DC stabilized voltage source for supplying power to the high voltage pulse modulating power source; a plurality of solid-state switches; a plurality of triggers corresponding to said plurality of solid-state switches, wherein each trigger provides a trigger signal to its corresponding solid-state switch to turn on said corresponding solid-state switch, wherein said plurality of triggers are divided into at least two groups of triggers; a time sequence control module, which, at time t1, controls said plurality of triggers to generate trigger signals so as to turn on said plurality of solid-state switches simultaneously, and at time t2, controls one group of said at least two groups of triggers to generate trigger signals to turn on solid-state switches corresponding to this group of triggers, wherein time t1 and time t2 appear alternately.

A broadband impulse generator includes a first delay line and a second delay line that receive an input signal and include a plurality of delay elements connected in series with each other, an oscillation signal generator that generates an oscillation signal having a certain number of pulses during a target impulse duration based on the input signal and an output signal of the first delay line, an envelope signal generator that generates a plurality of envelope signals having a delay duration with each other and having a certain voltage level during the target impulse duration, based on the input signal and an output signal of the second delay line, and an impulse signal generator that generates an impulse signal having the certain number of pulses during the target impulse duration based on the plurality of impulse signals and the oscillation signal.

A broadband impulse generator includes a first delay line and a second delay line that receive an input signal and include a plurality of delay elements connected in series with each other, an oscillation signal generator that generates an oscillation signal having a certain number of pulses during a target impulse duration based on the input signal and an output signal of the first delay line, an envelope signal generator that generates a plurality of envelope signals having a delay duration with each other and having a certain voltage level during the target impulse duration, based on the input signal and an output signal of the second delay line, and an impulse signal generator that generates an impulse signal having the certain number of pulses during the target impulse duration based on the plurality of impulse signals and the oscillation signal.

A spread spectrum clock generator includes a phase comparator that compares a reference clock with a feedback clock, a low-pass filter that passes a predetermined low-frequency component, a phase lock loop that includes a voltage-controlled oscillator generating an output clock whose frequency corresponds to the filtered signal, a triangular wave controller that generates a triangular wave signal for frequency-modulating the spread spectrum clock based on the output clock, a delay controller that generates the feedback clock by controlling delay of the output clock based on the triangular wave signal, a first counter that counts the output clock and output a first count value, a second counter that counts the reference clock and output a second count value, and a phase error correction circuit that compares the first count value with the second count value and corrects phase error of the output clock.