A plumbing fitting includes a housing and a missing valve. The housing includes a first aperture, a second aperture, a third aperture, and a mixing chamber in fluid communication with the first aperture, the second aperture, and the third aperture. The mixing valve is disposed within the housing. The mixing valve includes a first flow control valve that is configured to control a first flow of fluid from the first aperture to the mixing chamber.

A flexible paint hose has a first end, a second end, and a continuous conduit wall extending from the first end to the second end. The continuous conduit wall has a cross-section absent of an edge, and a non-circular cross-sectional shape in a first state and a substantially circular cross-sectional shape in a second state.

An apparatus that includes a housing with an input port and a first output port. A piston is disposed within a bore of the housing and includes a bypass via disposed transversely within the bore and a bypass tube disposed longitudinally within the bore. The bypass tube is configured to provide a flow path from the bypass via to a second output port on the bypass tube. The piston includes a sleeve disposed concentrically around the bypass tube. An interior chamber is defined by an exterior surface of the sleeve and an interior surface of the bore of the housing. The piston is configurable between a first configuration that provides a first flow path between the input port and the first output port via the interior chamber and a second configuration that provides a second flow path between the input port and the second output port via the bypass tube.

An apparatus for filling product into containers includes a working chamber through which the containers pass and the containers are acted upon by a sterile fluid to avoid contamination. An external line extends through the working chamber having a plurality of gas openings for the introduction of sterile air into the working chamber and that an internal line extends into the external line having a plurality of openings for spraying a cleaning medium. An annular chamber extends in a longitudinal direction between the internal and the external line. The cross-sectional area of the annular chamber varies in the longitudinal direction so that an even distribution of sterile air emerging from the gas openings into the working chamber is achieved.

Described is a method for purging a fluid channel is a low pressure gradient formation liquid flow system. Control of the fluid channels for multiple solvents allows for one or more static volumes of solvents not intended for use in an isocratic flow to be purged from their fluid channels to avoid contamination of the isocratic solvent. Advantageously, the method avoids the need to modify equipment or to reconfigure a pumping system so that the inlet is directly coupled to a single solvent source. Thus there is no need to bypass existing valves and liquid coupling components where solvents are combined during conventional gradient operation.

The invention provides a passive fluidics circuit for directing different fluids to a common volume, such as a reaction chamber or flow cell, without intermixing or cross contamination. The direction and rate of flow through junctions, nodes and passages of the fluidics circuit are controlled by the states of upstream valves (e.g. opened or closed), differential fluid pressures at circuit inlets or upstream reservoirs, flow path resistances, and the like. Free diffusion or leakage of fluids from unselected inlets into the common outlet or other inlets at junctions or nodes is prevented by the flow of the selected inlet fluid, a portion of which sweeps by the inlets of unselected fluids and exits the fluidics circuit by waste ports, thereby creating a barrier against undesired intermixing with the outlet flow through leakage or diffusion.

A mixing valve includes a mixing chamber, a first flow control valve having a first flow control opening, and a second flow control valve having a second flow control opening. The first and second flow control openings each have a diameter of approximately six millimeters and the mixing valve has a flow coefficient of approximately 2.5 when both flow control valves are in a mid-open position.

Dialysis systems and methods are described which can include a number of features. The dialysis systems described can be to provide dialysis therapy to a patient in the comfort of their own home. The dialysis system can be configured to prepare purified water from a tap water source in real-time that is used for creating a dialysate solution. The dialysis systems described also include features that make it easy for a patient to self-administer therapy. For example, the dialysis systems include disposable cartridge and patient tubing sets that are easily installed on the dialysis system and automatically align the tubing set, sensors, venous drip chamber, and other features with the corresponding components on the dialysis system. Methods of use are also provided, including automated priming sequences, blood return sequences, and dynamic balancing methods for controlling a rate of fluid transfer during different types of dialysis, including hemodialysis, ultrafiltration, and hemodiafiltration.

A mixing valve that includes a housing having a first outlet, a second outlet, and a mixing chamber; a first flow control valve for controlling flow through the first outlet to the mixing chamber; and a second flow control valve for controlling flow through the second outlet to the mixing chamber; wherein the housing has a length dimension, a width dimension, and a thickness dimension, and the largest of these dimensions is no more than approximately 65 millimeters.

During the production of consumable liquids such as milk, soup, and juice, the liquid consumable may be transferred from one location to another location through a fluid conduit. For example, a consumable liquid may be transferred from a storage tank to another destination through piping. At the end of the process, the piping may be purged with a flushing fluid to push the liquid consumable remaining in the piping to the end destination, thus preventing the volume of liquid remaining in the piping from being wasted. To control the flushing processing, fluid flowing through the piping may be fluorometrically analyzed to determine a concentration of product in the fluid. The flushing liquid can then be controlled based on the determined concentration. For example, the supply of flushing liquid may be terminated when the concentration of product falls below a threshold, indicating the flushing liquid is diluting the liquid consumable.