SUPERCONTINUUM LIGHT SOURCE COMPRISING TAPERED MICROSTRUCTURED OPTICAL FIBER
20200326474 ยท 2020-10-15
Assignee
Inventors
Cpc classification
G02B6/02214
PHYSICS
H01S3/06725
ELECTRICITY
H01S3/09415
ELECTRICITY
G01B9/02007
PHYSICS
H01S3/06741
ELECTRICITY
G02B6/02347
PHYSICS
G02F1/353
PHYSICS
G02B6/02338
PHYSICS
G01B9/02091
PHYSICS
H01S3/0092
ELECTRICITY
G02B6/02333
PHYSICS
International classification
H01S3/00
ELECTRICITY
Abstract
The invention relates to a supercontinuum light source comprising a microstructured optical fiber and a pump light source. The microstructured optical fiber comprises a core and a cladding region surrounding the core, as well as a first fiber length section, a second fiber length section and an intermediate fiber length section between said first and second fiber length sections. The first fiber length section comprises a core with a first characteristic core diameter. The second fiber length section comprises a core with a second characteristic core diameter, smaller than said first characteristic core diameter, where said second characteristic core diameter is substantially constant along said second fiber length section. The intermediate length section of the optical fiber comprises a core which is tapered from said first characteristic core diameter to said second characteristic core diameter over a tapered length.
Claims
1. A supercontinuum light source comprising: i. a microstructured optical fiber for generating supercontinuum light responsive to being pumped, and ii. a pump light source arranged to pump said microstructured optical fiber with pump light having a first wavelength, .sub.1; wherein: said microstructured optical fiber has a length and a longitudinal axis along its length and comprises a core region that is capable of guiding light along the longitudinal axis of said microstructured optical fiber and a first cladding region surrounding said core region; said microstructured optical fiber comprises a first fiber length section, a second fiber length section as well as an intermediate fiber length section between the first and second fiber length sections; the core region of said first fiber length section has a first characteristic core diameter W.sub.1, the core region of said second fiber length section has a second characteristic core diameter W.sub.2, where said second characteristic core diameter W.sub.2 is smaller than said first characteristic core diameter W.sub.1, and where said second characteristic core diameter W.sub.2 is substantially constant along said second fiber length section; the characteristic core diameter of the core region of said intermediate fiber length section of the microstructured optical fiber is tapered from the first characteristic core diameter W.sub.1 to the second characteristic core diameter W.sub.2 over a tapered length L.sub.i; and wherein said second fiber length section has zero dispersion at a wavelength ZDW.sub.2, where ZDW.sub.2 is in the range from about .sub.1150 nm to about .sub.1+50 nm, and wherein said second fiber length section has anomalous dispersion at wavelengths above said ZDW.sub.2.
2. The supercontinuum light source according to claim 1 wherein said first characteristic core diameter W.sub.1 is larger than about 7 m.
3. The supercontinuum light source according to claim 2, wherein said second characteristic core diameter W.sub.2 is larger than about 3.5 m.
4. (canceled)
5. The supercontinuum light source according to claim 1 where said microstructured optical fiber comprises microstructure elements embedded in a base material, wherein the refractive index of the core region of said microstructured optical fiber is equal to the refractive index of the base material.
6. The supercontinuum light source of claim 5 wherein said microstructure elements comprise holes.
7. The supercontinuum light source according to claim 1 wherein the refractive index of said core region of said microstructured optical fiber is substantially equal to the refractive index of silica glass.
8. The supercontinuum light source according to claim 1 wherein said first fiber length section has normal dispersion at said first wavelength .sub.1.
9. The supercontinuum light source according to claim 1 wherein said first fiber length section has a zero dispersion at a wavelength ZDW.sub.1, where ZDW.sub.1 is greater than about .sub.1+20 nm.
10. (canceled)
11. The supercontinuum light source according to claim 1 wherein said first fiber length section is single mode at least at the first wavelength .sub.1.
12. The supercontinuum light source according to claim 1 wherein an output pulse from said supercontinuum light source has an output spectral density over at least 50 nm between 400 nm and 900 nm of at least 500 nJ/10 nm.
13. The supercontinuum light source according to claim 1 wherein .sub.1 is from about 900 nm to about 1100 nm.
14-17. (canceled)
18. A photoacoustic imaging system comprising a supercontinuum light source according to claim 1, a detector for detecting ultrasonic emission waves and an image processor for forming an image of the detected ultrasonic waves.
19. A multimodal photoacoustic and optical coherence tomography (OCT) imaging acquisition system comprising the photoacoustic imaging system as claimed in claim 18 combined with an OCT imaging system comprising a detector for collecting reflected light and an image processor for forming an image of the detected reflected light, wherein the photoacoustic imaging system and the OCT imaging system use said supercontinuum light source as a common light source.
20. A supercontinuum light source comprising: i. a microstructured optical fiber for generating supercontinuum light responsive to being pumped, and ii. a pump light source arranged to pump said microstructured optical fiber with pump light having a first wavelength, .sub.1; wherein: said microstructured optical fiber has a length and a longitudinal axis along its length and comprises a core region that is capable of guiding light along the longitudinal axis of said microstructured optical fiber and a first cladding region surrounding said core region; said microstructured optical fiber comprises a first fiber length section, a second fiber length section as well as an intermediate fiber length section between the first and second fiber length sections; the core region of said first fiber length section has a first characteristic core diameter W.sub.1, the core region of said second fiber length section has a second characteristic core diameter W.sub.2, where said second characteristic core diameter W.sub.2 is smaller than said first characteristic core diameter W.sub.1, and where said second characteristic core diameter W.sub.2 is substantially constant along said second fiber length section; the characteristic core diameter of the core region of said intermediate fiber length section of the microstructured optical fiber is tapered from the first characteristic core diameter W.sub.1 to the second characteristic core diameter W.sub.2 over a tapered length L.sub.i; said second fiber length section has zero dispersion at a wavelength ZDW.sub.2, where ZDW.sub.2 is in the range from about .sub.1150 nm to about .sub.1+50 nm, and said second fiber length section has anomalous dispersion at wavelengths above said ZDW.sub.2; said first fiber length section has normal dispersion at said first wavelength .sub.1; said first characteristic core diameter is larger than about 7 m; and wherein said second characteristic core diameter is larger than about 3.5 m.
21. (canceled)
22. The supercontinuum light source according to claim 20 wherein .sub.1 is from about 700 nm to about 1100 nm.
23. The supercontinuum light source according to claim 20 wherein said first fiber length section has zero dispersion at a wavelength ZDW.sub.1, where ZDW.sub.1 is greater than about .sub.1+20 nm.
24. The supercontinuum light source according to claim 20 wherein an output pulse from said supercontinuum light source has an output spectral density over at least 50 nm between 400 nm and 900 nm of at least 500 nJ/10 nm.
25. A photoacoustic imaging system comprising a supercontinuum light source according to claim 20, a detector for detecting ultrasonic emission waves and an image processor for forming an image of the detected ultrasonic waves.
26. A multimodal photoacoustic and optical coherence tomography (OCT) imaging acquisition system comprising the photoacoustic imaging system as claimed in claim 25 combined with an OCT imaging system comprising a detector for collecting reflected light and an image processor for forming an image of the detected reflected light, wherein the photoacoustic imaging system and the OCT imaging system use said supercontinuum light source as a common light source.
27. A supercontinuum light source comprising: i. a microstructured optical fiber for generating supercontinuum light responsive to being pumped, and ii. a pump light source arranged to pump said microstructured optical fiber with pump light having a first wavelength, .sub.1; wherein: said microstructured optical fiber has a length and a longitudinal axis along its length and comprises a core region that is capable of guiding light along the longitudinal axis of said optical fiber and a first cladding region surrounding said core region; said microstructured optical fiber comprises a first fiber length section, a second fiber length section as well as an intermediate fiber length section between the first and second fiber length sections; the core region of said first fiber length section has a first characteristic core diameter the core region of said second fiber length section has a second characteristic core diameter W.sub.2, where said second characteristic core diameter W.sub.2 is smaller than said first characteristic core diameter W.sub.1, and where said second characteristic core diameter W.sub.2 is substantially constant along said second fiber length section; the characteristic core diameter of the core region of said intermediate fiber length section of the microstructured optical fiber is tapered from the first characteristic core diameter W.sub.1 to the second characteristic core diameter W.sub.2 over a tapered length L.sub.i; said second fiber length section has zero dispersion at a wavelength ZDW.sub.2, where ZDW.sub.2 is in the range from about .sub.1150 nm to about .sub.1+50 nm, and said second fiber length section has anomalous dispersion at wavelengths above said ZDW.sub.2; .sub.1 is from about 700 nm to about 1100 nm; said first characteristic core diameter is larger greater than about 7 m; said second characteristic core diameter is larger than about 3.5 m; said first fiber length section has normal dispersion at said first wavelength .sub.1; wherein said first fiber length section has a zero dispersion at a wavelength ZDW.sub.1, where ZDW.sub.1 is greater than about .sub.1+20 nm; and wherein an output pulse from said supercontinuum light source has an output spectral density over at least 50 nm between 400 nm and 900 nm of at least 500 nJ/10 nm.
28. (canceled)
Description
BRIEF DESCRIPTION OF DRAWINGS
[0068] The invention will be explained in more detail below in connection with preferred embodiments and with reference to the drawings in which:
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[0079] The figures are schematic and are simplified for clarity. Throughout, the same reference numerals are used for identical or corresponding parts.
[0080] Further scope of applicability of the present invention will become apparent from the detailed description given hereinafter. However, it should be understood that the detailed description and specific examples, while indicating preferred embodiments of the invention, are given by way of illustration only, since various changes and modifications within the spirit and scope of the invention will become apparent to those skilled in the art from this detailed description.
[0081] The invention is defined by the features of the independent claim(s). Preferred embodiments are defined in the dependent claims. Any reference numerals in the claims are intended to be non-limiting for their scope.
[0082] Some preferred embodiments have been described in the foregoing, but it should be stressed that the invention is not limited to these, but may be embodied in other ways within the subject-matter defined in the following claims.
[0083] With reference to
[0084] The microstructured optical fiber 1 has a length consisting of a length 7 of the microstructured fiber as well as a length 8 of an end cap, as well as an outer diameter D. The microstructures of the microstructured fiber 1 are holes. These holes have been collapsed as shown in the figure in the area of fiber length 7 adjacent to the end cap 8. One way of carrying out such a collapse is by heating of the optical fiber 1.
[0085] In this prior art embodiment, the microstructured fiber is a non-tapered fiber. The characteristic diameter of the core is of the order of magnitude some m, typically 3.5 or 5 m; the extension of the end cap length 8 in the longitudinal axis of the fiber is of a magnitude of 100 m, e.g. 200 m, whilst the microstructured fiber length is e.g. several meters, for example 10 meters.
[0086] Light has been fed into the fiber; the reference number 4 indicates light confined within the core region of the fiber 1, reference number 5 indicates light spreading from the core region of the length 7 of the fiber into the end cap 8, whilst reference number 6 indicates light exiting from the end cap 8 of the optical fiber 1. It may be seen that the light spreads out in the region of the collapsed microstructures and in the end cap 8 compared to the length 7.
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[0090] The optical fiber 10, along its length, comprises a first fiber length section 12, a second fiber length section 14 as well as an intermediate fiber length section 13 between the first and second fiber length sections 12, 14.
[0091] In one embodiment the total length of the optical fiber 10 is such as less than about 50 m, such as less than about 30 m, such as less than about 20 m.
[0092]
[0093] The intermediate fiber length section 13 of the optical fiber 10 comprises a core region which is tapered from the first characteristic core diameter W.sub.1 to the second characteristic core diameter W.sub.2 over a tapered length L.sub.i.
[0094] The first fiber length section 12 has normal dispersion at the first wavelength .sub.1 and the second fiber length section has zero dispersion at a second wavelength ZDW.sub.2, where ZDW.sub.2 is up to about .sub.1+50 nm. The second fiber length section has anomalous dispersion at wavelengths above the second wavelength ZDW.sub.2.
[0095]
[0096] Referring again to
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[0099] As an example only, the characteristic core diameter at the first fiber length section is 5 m and the characteristic core diameter at the second fiber length section is 10 m.
[0100] It is an insight of the inventors that fiber damage due to high optical peak powers and/or pulse energies often takes place at the transition between the end cap and the first fiber length section 12, and not at the end cap input of the microstructured optical fiber. Therefore, by providing a fiber with enlarged input dimensions in the form of a fiber with a first fiber length section having enlarged core diameter compared to the second fiber length section, it is achieved that the microstructured optical fiber is able to receive more peak power and/or pulse energy without being damaged. It is believed that this is due to the effect that the light fed into the first fiber length section is distributed over the large core in the first fiber length section.
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[0104] The pump laser 20 applied was a passive q-switched laser, comprising a Nd:YAG crystal combined with a Cr:YAG. The backside of the Nd:YAG was coated with HR coating at 1064 nm and a semi-transparent mirror with a 60% reflection @1064 was placed in front of the Cr:YAG. The cavity was pumped using an 808 nm diode pump. The resulting laser cavity emitted pulsed light at 1064 nm with a repetition rate of app. 18-20 kHz and a pulse width of 1.2 ns. Measured output power was 600 mW, but with a portion of this light arising from non-absorbed pump laser light (residual 808 nm light).
[0105] The pump laser was attempted coupled into the commercially available fiber SC-5.0-1040 from NKT Photonics. The fiber has pitch =3.3 m, and relative hole size d/=0.52 giving core size 5 m. It was observed that the laser damaged the fiber in such a way that no light could be transmitted and that the damage seemed to occur instantaneously. This is a typical failure mechanism when the pulse energy is too high.
[0106] It is known from prior tests that the SC-5.0-1040 can withstand 1.2 ns laser pulses at 1064 nm having pulse peak power in the range of 10-12 kW, and that such pulses generate a broad supercontinuum from 0.5 to 2.4 m in the fiber. This fiber is used for NKT Photonics commercial product SuperK Compact.
[0107] The pump laser 20 was applied to an example of the microstructured optical fiber of the invention comprising an intermediate tapered fiber length section in order to prove that this fiber could sustain the pulse peak power which a normal non-linear fiber cannot.
[0108] The microstructured optical fiber used for the experiment had the following characteristics:
[0109] d/=0.52 in the first fiber length section, the second fiber length section as well as in the intermediate fiber length section;
[0110] Characteristic core diameter in first fiber length section: 10 m;
[0111] Characteristic core diameter in second fiber length section: 5 m;
[0112] Length of first fiber length section: app. 1 m (0.1 m);
[0113] Length of taper, viz. intermediate fiber length section: app. 1 m (0.1 m);
[0114] Total length of the microstructured optical microstructured fiber: app. 15 m (0.5 m).
[0115] Both ends of the microstructured optical fiber were cleaved and collapsed with a 200 m25 m collapse length, giving end caps.
[0116] The input end of the microstructured optical fiber viz. the input end of the first fiber length section, was positioned in front of the pump laser, and a pair of lenses was used to couple the light from the pump laser into the fiber. The lens pair consisted of a collimating lens having a 100 mm focal length and a focusing lens having a focal length of 3.5 mm. The two lenses were separated by a distance of app. 30 mm. The lenses were aligned in the x- and y-axis until seed light was coupled into the core of the microstructured optical fiber. Focus on the fiber was achieved by moving the microstructured optical fiber end towards the focusing lens until maximum power was measured using a thermal detector from Ophir Optronics (Ophir power head model #3A).
[0117] The alignment procedure continued until maximum power out of the microstructured optical fiber was measured. This was achieved around 70 mW output power.
[0118] Once a supercontinuum was achieved through the tapered microstructured optical fiber, the result was recorded using an Optical Spectrum Analyser (OSA) from ANDO, model #6315B. A spectrum was recorded from 400 to 1750 nm with a 5 nm resolution. The spectrum was recorded through an integrating sphere (Ocean Optics) with a multimode fiber having an 01 mm fiber core.
[0119] The coupling from the seed laser into the tapered microstructured optical fiber operated at maximum achieved output power (app. 70 mW) for app. 10 minutes in order to verify that the microstructured optical fiber core would not burn due to the increased pulse peak power. In contrast when the laser was fed directly into the prior art fiber SC-5.0-1040, the core of the optical fiber was destroyed within a few seconds once optimal power has been achieved due to the high peak power and pulse energy of the pump source. A significant portion of the measured 600 mW input power is believed to arise from non-absorbed 808 nm pump light which can be seen in the spectrum. To achieve the best injection efficiency into single-mode fiber, the direction, position, size and divergence of the beam from the pump light source are advantageously all optimized. In the present experiment, is believed that the lens pair was not optimally aligned with respect to the core of the microstructured optical fiber resulting in a significant portion of light being lost instead of reaching the microstructured optical fiber. Thus, it is believed that considerable more output power is achievable, in the order of magnitude 200-300 mW.
[0120] The experiment demonstrates that the first fiber length section having an enlarged size compared to the second fiber length section and compared to the standard non-linear fiber is capable of coupling the light into the second fiber length section which is here a single mode part of the microstructured optical fiber, thus creating a supercontinuum. Thus, light in the first fiber length section and/or in the intermediate fiber length section does not exit the microstructured optical fiber at end of these the respective first and intermediate fiber length sections, but is being coupled into the core of the single mode structure in the second fiber length section of the microstructured optical fiber.
[0121] The experiment also demonstrates that the expanded input in the form of the first fiber length section having a large first characteristic core diameter is able to sustain a greater pulse peak power than the prior art non-linear supercontinuum fibers. This is seen in that the relatively high peak power provided by the pump laser tends to damage the input end facet of a prior art standard supercontinuum, non-linear fiber but did not damage the tapered microstructured fiber of an embodiment of the invention.
[0122] Thus, the experiment shows that the microstructured optical fiber according to the invention is useful for relatively high energy pulse power compared to prior art fibers used for SC generation.
[0123] In an embodiment of the invention, the pump laser 200 is a q-switched laser comprising an active feedback to control the emission frequency (repetition rate) of the pump laser, and/or to reduce the timing jitter between the pump laser pulses.
[0124] Passive Q-switched pump lasers comprising an absorbable absorber (e.g. a Cr:YAG Crystal) and a laser diode to pump the absorbable saturator (e.g. a CW laser diode with a peak wavelength at 808 nm) are well known in the art. Here pulses are emitted from the pump laser whenever the absorbable saturator becomes transparent (bleaches) thus changing the transmission through the crystal from a low transmission value to a high transmission value. This is e.g. described in the W. Koechner's book Solid-State Laser Engineering on pp. 522-523 (Springer, Sixth revised and Updated Edition, 2010, ISBN-13: 978-14419-2117-8). The repetition rate of the emitted pulse train is random in nature due to a number of limitations in the seed laser cavity (noise, fluctuation in input power, temperature fluctuation, etc.).
[0125] In an aspect the inventors has found that pump light source comprising a system for active feedback as shown in
[0126] The pump light source generally provides a very stable emission frequency (repetition rate) of the pump laser and/or a reduced timing jitter between the pump laser pulses.
[0127] In an embodiment the control is obtained by modulating the output from the laser diode. This might e.g. be obtained by detecting whenever a pulse is emitted from the pump laser 200. The feedback signal is used to switch the laser diode from ON (emitting light) to OFF (no emission).
[0128]
[0129] In the embodiment illustrated in
[0130] When the laser diode 30 is turned ON it will start to pump energy into the pump laser cavity 31. No light is emitted from the pump laser until the saturation state of the absorbable saturator is changed allowing light from the seed laser cavity to emit a pulse. When the pulse is emitted from the pump laser it will be detected by the photodiode 32. The signal from the photodiode is sent to a control unit 33, which sends a signal to the laser diode to shut it OFF thus preventing further light to be pumped into the laser cavity.
[0131] With the laser diode turned OFF no light is pumped into the pump laser cavity, and consequently no further seed laser pulses are emitted. The laser diode may be turned to ON again whenever a new pulse is requested by the supercontinuum laser system. This request may either be at a constant frequency or by a user trigger input. The maximum obtainable repetition rate is achieved when the requested frequency exceeds the pump capacity of the pump source laser. This happens when a new pulse is requested before the previous pulse is yet emitted from the pump laser. The laser diode will then operate continuously providing the maximal repetition rate possible by the pump laser.
[0132] During the laser diode OFF state the laser may be kept on a threshold level where no light is emitted from the laser. Keeping the laser diode at threshold will enable a faster rise time of the laser diode unit and thus a faster response of the pump laser.
[0133] The use of active feedback enables full control of the pump laser repetition rate up to the level where the laser diodes operates continuously, which typically occurs at a pump laser repetition rate of 40-50 kHz. Furthermore a much more stable pulse-to-pulse signal will be obtained as the pulse-to-pulse jitter is only dependent on the amount of energy (and thus time) the laser diode requires in order to provide sufficient energy for the pump laser to emit a pulse. The timing jitter between pulse emissions from the pump laser is reduced to a few hundred ns (100-300 ns) where a normal passive q-switched pump laser may have a pulse-to-pulse jitter in the range of a few ms (2-10 ms). As the pump laser only acquires the amount of energy sufficient in order to emit a single pulse at a time, the emitted pulse itself is expected to be less sensitive to pulse jitter such as pulse width jitter and pulse amplitude jitter.
[0134] In one embodiment of the invention the pump laser has a variable repletion rate.
[0135] In one embodiment of the invention the pump laser pulses are externally triggered. This could e.g. by used in connection with a measurement method having a finite sampling time, where it is advantageous having the same number of pulses within each of the sampling intervals. One example is where for hyperspectral imaging with a given shutter time.
[0136] In one embodiment of the invention the pump laser timing jitter is such as less than about 1 ms, such as less than about 500 ns, such as less than about 300 ns, such as less than about 200 ns.
[0137] The supercontinuum light source of the invention has been found to be highly suitably for performing photoacoustic imaging due to its ability to generate supercontinuum pulses with very high pulse energy.
[0138] The invention also comprises a photoacoustic imaging system comprising a supercontinuum light source as described above, a detector for detecting ultrasonic emission waves and an image processor for forming an image of the detected ultrasonic waves. The detector can be any that is suitable for ultrasonic emission waves, preferably with a high sensitivity e.g. such as ultrasonic emission waves used in prior art photoacoustic imaging systems. The processor for forming an image of the detected ultrasonic waves can for example be in prior art photoacoustic imaging system.
[0139] Photoacoustic imaging is well known and is based on the photoacoustic effect. In photoacoustic imaging, non-ionizing laser pulses are delivered into biological tissues. Some of the delivered energy will be absorbed and converted into heat, leading to transient thermoelastic expansion and thus wideband (e.g. MHz) ultrasonic emission. The generated ultrasonic waves are then detected by ultrasonic transducers to form images. It is known that optical absorption is closely associated with physiological properties, such as hemoglobin concentration and oxygen saturation. As a result, the magnitude of the ultrasonic emission (i.e. photoacoustic signal), which is proportional to the local energy deposition, reveals physiologically specific optical absorption contrast. 2D or 3D images of the targeted areas can then be formed.
[0140] The invention further comprises a method of performing photoacoustic imaging of a biological tissue the method comprising providing a photoacoustic imaging system as described above and delivering supercontinuum laser pulses from said supercontinuum light source to said biological tissue and collecting ultrasonic emission waves from said biological tissue by said detector and forming the image using said image processor.
[0141] Due to the very high power and pulse energy of the supercontinuum light source of the invention, the supercontinuum light source has further been found to be very suitable for use in multimodal imaging, e.g. combining photoacoustic and optical coherence tomography (OCT) imaging. The invention therefore also relates to a multimodal photoacoustic and optical coherence tomography (OCT) image acquisition system comprising photoacoustic imaging system as described above combined with an OTC imaging system, wherein the photoacoustic imaging system and the OTC imaging system using said supercontinuum light source as a common light source, said multimodal photoacoustic and optical coherence tomography (OCT) image acquisition system preferably further comprises a detector for collecting reflected light and an image processor for forming an image of the detected reflected light.
[0142] Optical coherence tomography is an established medical imaging technique. It is widely used, for example, to obtain high-resolution images of the anterior segment of the eye and the retina. OTC is advantageous for delivering high resolution because it is based on light, rather than sound or radio frequency. An optical beam is directed at the tissue to be analyzed, and a small portion of this light that reflects from sub-surface features is collected. Most of the light is not reflected but, rather, scatters off at large angles. The OCT uses a technique called interferometry to record the optical path length of received photons allowing rejection of most photons that scatter multiple times before detection. Thus OCT can build up clear 3D images of thick samples by rejecting background signal while collecting light directly reflected from surfaces of interest. The invention is in particular suited for spectral domain OCT.
[0143] The multimodal photoacoustic and optical coherence tomography (OCT) image acquisition system preferably comprises a filter for selecting a spectral portion of the light beams to be applied in the OTC. Due to the very high power the multimodal photoacoustic and optical coherence tomography (OCT) image acquisition system advantageously comprises an intensity filter for reducing the intensity applied in OCT in dependence on the subject to be analyzed. Where OCT is applied for analysis of sensitive tissue, such as eye tissue, it is desired that the intensity is kept relatively low in order not to damage the tissue.
[0144] It should be emphasized that the term comprises/comprising when used herein is to be interpreted as an open term, i.e. it should be taken to specify the presence of specifically stated feature(s), such as element(s), unit(s), integer(s), step(s) component(s) and combination(s) thereof, but does not preclude the presence or addition of one or more other stated features.
[0145] All features of the inventions including ranges and preferred ranges can be combined in various ways within the scope of the invention, unless there are specific reasons for not to combine such features.
[0146] Some embodiments have been shown in the foregoing, but it should be stressed that the invention is not limited to these, but may be embodied in other ways within the subject-matter defined in the following claims. Various modifications and applications may occur to those skilled in the art without departing from the true spirit and scope of the invention as defined in the appended claims.