B01L13/00

Fluid connector

Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.

Photocleavage method and apparatus to clean fluidic devices

A method and system for improving throughput of a fluidic system such as a biopolymer analysis system by cleaning accumulated or clogging biopolymer from the fluidic system is disclosed. The method and system utilize a light energy source to photocleave the biopolymer molecules that may accumulate or aggregate in the fluidic system or clog a passageway. The accumulated biopolymer may be exposed to a light energy source for a sufficient period of time such that the biopolymer molecule is dosed with sufficient energy to photocleave the biopolymer molecules, thereby restoring the efficiency of and flow through the system.

METHOD AND DEVICE FOR PERFORMING HETEROGENEOUS IMMUNOASSAYS
20210270819 · 2021-09-02 ·

Aspects of the present disclosure are directed to a device for carrying out heterogeneous immunoassays by means of magnetic particles in cuvettes lined up next to one another, wherein each cuvette has a filling opening and at least one lateral measurement window which is transparent to the measurement radiation. In one embodiment, the device includes at least one stationary cuvette array in which the cuvettes are arranged for receiving liquid media, at least one support arm which is movable along the cuvette array and which is lowerable toward the filling opening of a selected cuvette. The support arm having at least one aspirating needle which is lowerable toward the bottom of the cuvette, and also having at least one dispenser which can be positioned above or in the respective filling opening for dispensing the liquid media into the cuvette.

Maintenance Reservoir
20210247411 · 2021-08-12 · ·

A maintenance reservoir for a digital dispense system. The maintenance reservoir includes an elongate trough disposed in a micro-well plate holder for holding fluid dispensed from a fluid droplet ejection head of a fluid droplet cartridge in the digital dispense system. The maintenance reservoir is disposed in the micro-well plate holder on at least one side of a micro-well plate and includes a position indicator to signify if the elongate trough is present or absent from the micro-well plate holder.

MICROFLUIDIC STRUCTURE, MICROFLUIDIC CHIP AND DETECTION METHOD

The present disclosure discloses a microfluidic structure, a microfluidic chip and a detection method. The microfluidic structure includes: a first base substrate and a second base substrate opposite to each other, an antibody area located between the first base substrate and the second base substrate and storing an enzyme-labeled first antibody, a cleaning area storing cleaning liquid, a signal substrate area storing a signal substrate solution and a detection area with a second antibody and an ion sensitive film fixed thereon, wherein all channel areas from the antibody area, the cleaning area and the signal substrate area to the detection area each have a driving electrode structure driving liquid drops to move; and the detection area has a thin film transistor connected with the ion sensitive film.

SYSTEMS AND METHODS FOR CELL PROCESSING

Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.

FLUID CONNECTOR

Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.

SPRAY ARM SPEED REGULATOR
20210162431 · 2021-06-03 · ·

Rotational speed of a spray arm is regulated based on centrifugal force and a liquid jet to create a variable angle corner spray nozzle. The regulator includes a weight on a pivot and a fluid jet, the weight having a curved surface to produce a variable angle corner spray nozzle depending on the weight angle. Centrifugal force created during rotation pushes the weight outward, which increases as the spray arm rotation speed increases. The liquid jet is located out from a pivot point and tends to push the weight inward. The pushing force of the liquid jet is maximum when the weight is most inward and minimum when the weight is most outward. The regulator stabilizes the arm speed at a specific speed independent from center pivot friction and the spray arm nozzle's orientation tolerance. Speed stabilizes when centrifugal force on the weight is equal to the pushing force of the fluid jet.

BLOOD COAGULATION ANALYSIS DEVICE AND METHOD OF CLEANING DISPENSATION NOZZLE

A cleaning condition of a first nozzle can be set for each reagent combination in a controller of a blood coagulation analysis device, the reagent combination indicating a combination of a reagent previously dispensed by the first nozzle and a reagent currently dispensed by the first nozzle. When the controller of the blood coagulation analysis device obtains the reagent combination and the cleaning condition of the first nozzle is set for the obtained reagent combination, the controller performs control to clean the first nozzle under the set cleaning condition.

GENERAL-PURPOSE FLUORESCENT FLUID PHOTOCHEMICAL MICROREACTOR AND MANUFACTURING METHOD THEREFOR BY 3D PRINTING
20210101145 · 2021-04-08 ·

Disclosed are a general-purpose fluorescent fluid photochemical microreactor and a manufacturing method therefor by means of 3D printing, belonging to the technical field of photochemical reactor research. By using a transparent photosensitive resin and the strong space building capacity of 3D printing, a photochemical microreactor having both a light-collecting channel and a reaction channel is prepared. By means of introducing a light-collecting substance in a fluid form into a light channel, not only can play the role of light collection and wavelength conversion, which solves the difficulty of traditional photochemical reactors of light source matching, but also the light-collecting substance can be flexibly changed so as to meet the requirements of different photochemical reactions in the reaction channel, which greatly expands the application range of the reactor.