A probe for insertion into an organ of a patient includes a medical device and an optical sensor. The medical device is fitted at a distal end of the probe and configured to perform one or both of electrophysiological (EP) sensing and ablation of tissue inside the organ. The optical sensor is configured to locally acquire an optical signal indicative of a concentration of at least one gas in blood in the organ.

Systems configured to acquire temperature signals from an Abreu Brain Thermal Tunnel (ABTT), to analyze the temperatures signals, and to determine a condition of a human body from the analysis, and a method for doing the same, are described. In addition, systems for application of thermal signals to the ABTT for treatment of conditions are described.

A method for detecting tumor tissue boundaries or a tumor stromal cell distribution range, more specifically, a diagnostic or non-diagnostic method for determining the boundaries of a tumor tissue; the boundaries of the tumor tissue are determined by means of determining the boundaries of the tumor stromal cells in the tumor tissue. The present method can more accurately determine the boundaries of tumor tissue, which serves to more accurately instruct the treatment of tumors, especially with respect to surgical treatment.

A radiation therapy system comprising a therapeutic radiation system (e.g., an MV X-ray source, and/or a linac) and a co-planar imaging system (e.g., a kV X-ray system) on a fast rotating ring gantry frame. The therapeutic radiation system and the imaging system are separated by a gantry angle, and the gantry frame may rotate in a direction such that the imaging system leads the MV system. The radiation sources of both the therapeutic and imaging radiation systems are each collimated by a dynamic multi-leaf collimator (DMLC) disposed in the beam path of the MV X-ray source and the kV X-ray source, respectively. In one variation, the imaging system identifies patient tumor(s) positions in real-time. The DMLC for the imaging radiation source limits the kV X-ray beam spread to the tumor(s) and/or immediate tumor regions, and helps to reduce irradiation of healthy tissue (e.g., reduce the dose-area product).

A method and system for non-invasive assessment and therapy planning for coronary artery disease from medical image data of a patient is disclosed. Geometric features representing at least a portion of a coronary artery tree of the patient are extracted from medical image data. Lesions are detected in coronary artery tree of the patient and a hemodynamic quantity of interest is computed at a plurality of points along the coronary artery tree including multiple points within the lesions based on the extracted geometric features using a machine learning model, resulting in an estimated pullback curve for the hemodynamic quantity of interest. Post-treatment values for the hemodynamic quantity of interest are predicted at the plurality of points along the coronary artery tree including the multiple points within the lesions for each of one or more candidate treatment options for the patient, resulting in a respective predicted post-treatment pullback curve for the hemodynamic quantity of interest for each of the one or more candidate treatment options. A visualization of a treatment prediction for at least one of the candidate treatment options is displayed.

Provided is a simulation phantom including a simulated target volume and a simulated normal tissue encasing the simulated target volume, wherein the simulated target volume and a portion of the simulated normal tissue abutting the simulated target volume have a first characteristic to enable the simulation phantom to be imaged on a first imaging device, and the simulated target volume and the portion of the simulated normal tissue abutting the simulated target volume further have a second characteristic to enable the simulation phantom to be imaged on a second imaging device different from the first imaging device.

A method of analyzing neurophysiological data recorded from a subject is disclosed. The method comprises identifying activity-related features in the data, and parceling the data according to the activity-related features to define a plurality of capsules, each representing a spatiotemporal activity region in the brain. The method further comprises comparing at least some of the defined capsules to at least one reference capsule, and estimating a brain function of the subject based on the comparison.

Systems and methods for generating an ablation map identifying target ablation locations on a heart of a patient are provided. One or more input medical images of a heart of a patient and a voltage map of the heart of the patient are received. An ablation map identifying target ablation locations on the heart is generated using one or more trained machine learning based models based on the one or more input medical images and the voltage map. The ablation map is output.

A device and a process for performing high temporal- and spatial-resolution MR imaging of the anatomy of a patient during intensity modulated radiation therapy (IMRT) to directly measure and control the highly conformal ionizing radiation dose delivered to the patient for the treatment of diseases caused by proliferative tissue disorders. This invention combines the technologies of open MRI, multileaf-collimator or compensating filter-based IMRT delivery, and cobalt teletherapy into a single co-registered and gantry mounted system.

The present invention relates to a hybrid imaging system for photodiagnosis and phototherapy and, more particularly, to a hybrid imaging system for photodiagnosis and phototherapy, which simultaneously acquires a visible ray image or a near-infrared ray image and a lonq wave infrared ray image by using an optical method. The hybrid imaging system for photodiagnosis and phototherapy according to the present invention includes a light distribution unit, a visible ray/near-infrared ray measurement unit, a long wave infrared ray measurement unit, and a light source unit, thereby simultaneously and quickly extracting a visible ray image, a near-infrared ray image, and a long wave infrared ray image without mutual distortion.