Provided is the technique for efficiently using the phoresis medium contained in the phoresis medium container by minimizing the remaining phoresis medium as small as possible, and further lowering the running cost. The disclosure proposes the measurement system as an example, which includes an electrophoresis device and a computer. The electrophoresis device includes a phoresis medium container for storing a phoresis medium, a capillary having its inside filled with the phoresis medium, a delivery mechanism for delivering the phoresis medium in the phoresis medium container to the capillary, and a device control section for controlling an operation of the delivery mechanism. The computer calculates a deliverable number of times from an amount of the phoresis medium in the phoresis medium container and an estimated delivery amount of the phoresis medium delivered by the delivery mechanism (see FIG 16).

Provided is the technique for efficiently using the phoresis medium contained in the phoresis medium container by minimizing the remaining phoresis medium as small as possible, and further lowering the running cost. The disclosure proposes the measurement system as an example, which includes an electrophoresis device and a computer. The electrophoresis device includes a phoresis medium container for storing a phoresis medium, a capillary having its inside filled with the phoresis medium, a delivery mechanism for delivering the phoresis medium in the phoresis medium container to the capillary, and a device control section for controlling an operation of the delivery mechanism. The computer calculates a deliverable number of times from an amount of the phoresis medium in the phoresis medium container and an estimated delivery amount of the phoresis medium delivered by the delivery mechanism (see FIG 16).

The disclosure relates to an apparatus and associated method for concentration of polarizable molecules within a fluid medium. The apparatus comprising a structure defining a cavity, having a cross-sectional dimension of 200 nm or less; at least two translocation electrodes positioned relative to the structure to enable generation of a DC electric field passing through the cavity; and at least two trapping electrodes positioned relative to the structure to enable generation of a time-varying electric field proximal to the cavity inlet.

The present invention provides a method for quantifying a monoclonal (M-) protein in a sample of a subject, the method comprising the steps of:—subjecting a serum sample of a subject to serum protein electrophoresis (SPE) in a gel, preferably serum protein electrophoresis in an agarose gel, to separate serum proteins into different serum protein fractions, optionally followed by immunofixation electrophoresis (IFE) and further optionally involving immunostaining of the gel;—excising from said gel a gel part comprising, or suspected of comprising, a M-protein;—performing an enzymatic digestion of proteins present in said gel part in order to provide a peptide digest comprising at least one M-protein peptide;—subjecting said peptide digest comprising said at least one M-protein peptide to liquid chromatography-mass spectrometry (LC-MS) to determine a quantity of said at least one M-protein peptide, thereby quantifying said M-protein in said sample.

Cancer treatment using TTFields (Tumor Treating Fields) can be customized to each individual subject by obtaining cancer cells from the subject, determining an electrical characteristic (e.g., dielectrophoretic forces, cell membrane capacitance, etc.) of the cancer cells, determining a frequency for the TTFields based on the determined electrical characteristic, and treating the cancer by applying TTFields to the subject at the determined frequency. In addition, cancer treatment can be planned for each individual subject by obtaining cancer cells from the subject, determining an electrical characteristic of the cancer cells, predicting whether TTFields would be effective to treat the cancer based on the determined electrical characteristic, and treating the subject by applying TTFields if the prediction indicates that TTFields would be effective.

Cancer treatment using TTFields (Tumor Treating Fields) can be customized to each individual subject by obtaining cancer cells from the subject, determining an electrical characteristic (e.g., dielectrophoretic forces, cell membrane capacitance, etc.) of the cancer cells, determining a frequency for the TTFields based on the determined electrical characteristic, and treating the cancer by applying TTFields to the subject at the determined frequency. In addition, cancer treatment can be planned for each individual subject by obtaining cancer cells from the subject, determining an electrical characteristic of the cancer cells, predicting whether TTFields would be effective to treat the cancer based on the determined electrical characteristic, and treating the subject by applying TTFields if the prediction indicates that TTFields would be effective.

An electrophoresis apparatus includes a dilution unit, an electrophoresis unit, and a control device. The dilution unit dilutes a sample with dilution water. The electrophoresis unit analyzes the sample diluted by the dilution unit by electrophoresing the sample. The control device controls the dilution unit and the electrophoresis unit.

Disclosed are methods for performing capillary electrophoresis on two or more nucleic acid samples. The methods employ a forward voltage to move a first sample forward from an inlet to an interrogation region in the capillary, then a backward voltage to move the first sample backward, and then a forward voltage again to move the first sample and a second sample forward. Systems and apparatuses for performing capillary electrophoresis are also provided.

A method for producing a membrane device includes: forming an insulating film as a first film on a Si substrate; forming a Si film as a second film on the entire surface or a part of the first film; forming an insulating film as a third film on the second film; forming an aperture so as to pass through a part of the third film positioned on the second film and not to pass through the second film; etching a part of the substrate on one side of the first film with a solution that does not etch the first film; and etching a part or all of the second film on the other side of the first film with a gas or a solution that does not etch the first film and has an etching rate for the third film lower than an etching rate for the second film.

A method for producing a membrane device includes: forming an insulating film as a first film on a Si substrate; forming a Si film as a second film on the entire surface or a part of the first film; forming an insulating film as a third film on the second film; forming an aperture so as to pass through a part of the third film positioned on the second film and not to pass through the second film; etching a part of the substrate on one side of the first film with a solution that does not etch the first film; and etching a part or all of the second film on the other side of the first film with a gas or a solution that does not etch the first film and has an etching rate for the third film lower than an etching rate for the second film.