In some implementations, a system is capable of obtaining and processing both actively monitored and passively monitored data in parallel in order to improve the accuracy and the specificity by which pathological risks are identified for a user. Data indicating measured levels of one or more metabolic biomarkers and activity data associated with a user is obtained. A biological state for the user is determined based on the measured levels of the one or more metabolic biomarkers. One or more user inputs indicated within the activity data, and scores reflecting respective likelihoods that a particular user input indicates a change to one or more aspects of the biological state for the user for each of the one or more user inputs is determined. Data corresponding to the biological state for the user is then adjusted. A communication that is generated based on the adjusted data is then provided for output.

A component measurement apparatus includes: a chip insertion space for inserting a component measurement chip provided with a reagent that reacts with a component to be measured in a sample; a light emitting unit configured to emit radiation light to the component measurement chip in a state in which the component measurement chip is inserted into the chip insertion space; a light receiving unit configured to receive light transmitted through or reflected from the component measurement chip; and a control unit configured to determine whether there is a possibility that an incorrect processing mode has been selected for execution.

A component measurement apparatus includes: a chip insertion space for inserting a component measurement chip provided with a reagent that reacts with a component to be measured in a sample; a light emitting unit configured to emit radiation light to the component measurement chip in a state in which the component measurement chip is inserted into the chip insertion space; a light receiving unit configured to receive light transmitted through or reflected from the component measurement chip; and a control unit configured to determine whether there is a possibility that an incorrect processing mode has been selected for execution.

A test strip (12) includes a flow path (26) formed in a main body portion (20); a reagent portion (22b) provided in the flow path (26); and an intake portion (24) which is provided at a starting end of the flow path (26) and through which a sample is introduced into the flow path (26). The main body portion (20) is provided with a buffer space (28) communicating with a terminal end of the flow path (26), and a vent hole (30) opened at an outer surface of the main body portion (20) and communicating with the buffer space (28), and in a region where the buffer space (28) and the flow path (26) are connected, a cross-sectional area (Sb) of the buffer space (28) is larger than a cross-sectional area (S) of the flow path (26).

A test strip (12) includes a flow path (26) formed in a main body portion (20); a reagent portion (22b) provided in the flow path (26); and an intake portion (24) which is provided at a starting end of the flow path (26) and through which a sample is introduced into the flow path (26). The main body portion (20) is provided with a buffer space (28) communicating with a terminal end of the flow path (26), and a vent hole (30) opened at an outer surface of the main body portion (20) and communicating with the buffer space (28), and in a region where the buffer space (28) and the flow path (26) are connected, a cross-sectional area (Sb) of the buffer space (28) is larger than a cross-sectional area (S) of the flow path (26).

The present invention provides compositions and methods for determining a saccharide level in a sample. In particular, compositions and methods of the invention include a boronic acid moiety that forms a complex with a saccharide.

The present invention provides compositions and methods for determining a saccharide level in a sample. In particular, compositions and methods of the invention include a boronic acid moiety that forms a complex with a saccharide.

NADP-dependent oxidoreductase compositions, and electrodes, sensors and systems that include the same. Analyte sensors include an electrode having a sensing layer disposed thereon, the sensing layer comprising a polymer and an enzyme composition distributed therein. The enzyme composition includes nicotinamide adenine dinucleotide phosphate (NAD(P).sup.+) or derivative thereof; an NAD(P).sup.+-dependent dehydrogenase; an NAD(P)H oxidoreductase; and an electron transfer agent comprising a transition metal complex.

NADP-dependent oxidoreductase compositions, and electrodes, sensors and systems that include the same. Analyte sensors include an electrode having a sensing layer disposed thereon, the sensing layer comprising a polymer and an enzyme composition distributed therein. The enzyme composition includes nicotinamide adenine dinucleotide phosphate (NAD(P).sup.+) or derivative thereof; an NAD(P).sup.+-dependent dehydrogenase; an NAD(P)H oxidoreductase; and an electron transfer agent comprising a transition metal complex.

A single flex double-sided electrode useful in a continuous glucose monitoring sensor. In one example, a counter electrode is placed on the back-side of the flex and a work electrode is placed on the top-side of the sensor flex. The electrode is fabricated on physical vapor deposited metal deposited on a base substrate. Adhesion of the electrode to the base substrate is carefully controlled so that the electrode can be processed on the substrate and subsequently removed from the substrate after processing.