Methods for analysis of a glucuronide ligand-drug conjugate are provided.

Treating, and compositions for treating, a condition and/or a symptom associated with an effect of at least one element of the opioid system in an animal by administering to the animal (i) a therapeutically effective amount of at least one microorganism and/or of a prebiotic thereof, where the microorganism is capable of modulating an effect of at least one element of the opioid system of the animal and (ii) a therapeutically effective amount of at least one compound capable of modulating an effect of an element of the opioid system of the animal.

Compounds and methods for use in detecting pregabalin in a sample suspected of containing pregabalin are disclosed. Pregabalin derivatives are described for producing pregabalin conjugates. A pregabalin-immunogenic carrier conjugate may be used as an immunogen for the preparation of an anti-pregabalin antibody. A pregabalin-detectable label conjugate may be used in a signal producing system in pregabalin assays.

Provided are methods for labeling a pharmaceutical product to indicate the origin, and/or intended recipient, and/or a predetermined characteristic (e.g. geographic location) of an intended recipient of the pharmaceutical product. The methods include incorporating certain pharmaceutically inactive marker substances into the pharmaceutical product at manufacture.

Provided are methods for labeling a pharmaceutical product to indicate the origin, and/or intended recipient, and/or a predetermined characteristic (e.g. geographic location) of an intended recipient of the pharmaceutical product. The methods include incorporating certain pharmaceutically inactive marker substances into the pharmaceutical product at manufacture.

Methods and devices for sampling, processing and identifying use of a substance or substances of abuse are provided. Systems and kits for sampling, processing and identifying acute use of a substance of abuse is also provided.

An all-in-one handheld machine for testing drugs in hairs comprises a handheld shell, a control mechanism, a fluorescent immune reagent card test mechanism, an identity recognition mechanism, and a control instruction input unit communicatively connected to the control mechanism are provided in the shell; a shell surface is provided with a reagent card inlet that corresponds to a reagent card socket of the test mechanism; the control mechanism is controllably connected to the test mechanism and the identity recognition mechanism, and is communicatively connected with a communication unit; the control mechanism, the test mechanism and the identity recognition mechanism are all electrically connected to a power supply module. The invention can achieve the functions of identity card reading and wireless data transmission, and the test for trace drug residues in hairs, thereby meeting the requirements for rapidity, portability and accuracy of an on-site test.

An all-in-one handheld machine for testing drugs in hairs comprises a handheld shell, a control mechanism, a fluorescent immune reagent card test mechanism, an identity recognition mechanism, and a control instruction input unit communicatively connected to the control mechanism are provided in the shell; a shell surface is provided with a reagent card inlet that corresponds to a reagent card socket of the test mechanism; the control mechanism is controllably connected to the test mechanism and the identity recognition mechanism, and is communicatively connected with a communication unit; the control mechanism, the test mechanism and the identity recognition mechanism are all electrically connected to a power supply module. The invention can achieve the functions of identity card reading and wireless data transmission, and the test for trace drug residues in hairs, thereby meeting the requirements for rapidity, portability and accuracy of an on-site test.

A method for labeling urine in a subject using fluorophores is provided that allows for determining if a urine sample originates from the subject that accepted the administered fluorophore. The method comprises detection of the fluorophore in the urine sample with optical means. One suitable fluorophore is fluorescein sodium. The method may be suitable for ensuring that urine samples for drug, illicit substance or other substance tests are genuine.

A method for labeling urine in a subject using fluorophores is provided that allows for determining if a urine sample originates from the subject that accepted the administered fluorophore. The method comprises detection of the fluorophore in the urine sample with optical means. One suitable fluorophore is fluorescein sodium. The method may be suitable for ensuring that urine samples for drug, illicit substance or other substance tests are genuine.