An apparatus for measuring blood pressure includes: a pulse wave measurer including a first light source configured to emit a first light, a second light source configured to emit a second light, and a photodetector configured to measure a pulse wave signal of an object based on the first light emitted by the first light source onto the object and returning from the object; a force measurer configured to measure a contact force between the object and the pulse wave measurer; and a processor configured to control emission of the second light from the second light source based on the measured contact force, and configured to estimate blood pressure of the object based on the measured pulse wave signal and the measured contact force.

A system is provided for augmenting a three-dimensional (3D) model of a heart to indicate the tissue state. The system accesses a 3D model of a heart, accesses two-dimensional (2D) images of tissue state slices of the heart, and accesses source location information of an arrhythmia. The system augments the 3D model with an indication of a source location based on the source location information. For each of a plurality of the tissue state slices of the heart, the system augments a 3D model slice of the 3D model that corresponds to that tissue state slice with an indication of the tissue state of the heart represented by the tissue state information of that tissue state slice. The system then displays a representation of the 3D model that indicates the source location of the arrhythmia and the tissue state of the heart.

Disclosed are devices and methods for estimating blood pressure, which implement a pulse-transit-time-based blood pressure model that can be calibrated. Some implementations provide reliable and user friendly means for calibrating the blood pressure model using blood pressure perturbation methods and multiple sensors.

Embodiments of the presently-disclosed subject matter include methods and systems for measuring a level of a neurotransmitter in a subject. Embodiments of the present methods comprise displaying a fixation point, a reward target, and a non-reward target, and measuring one or more saccade movement parameters for reward saccades and non-reward saccades. The saccade movement parameters can include velocity, amplitude, reaction time, or a combination thereof. The present methods can further include determining a reward modulation of the subject, the reward modulation being equal to a difference between the reward and the non-reward values for a respective saccade movement parameter. Some embodiments further include identifying the subject as including a deficiency of the neurotransmitter if there is a statistically measurable difference between the reward modulation of the subject and a reference reward modulation and/or if the non-reward and the reward saccade movement parameters are statistically equivalent.

In a respiratory apparatus for treatment of sleep apnea and other disorders associated with an obstruction of a patient's airway and which uses an airflow signal, an obstruction index is generated which detects the flattening of the inspiratory portion of the airflow. The obstruction index is used to differentiate normal and obstructed breathing. The obstruction index is based upon different weighting factors applied to sections of the airflow signal thereby improving sensitivity to various types of respiration obstructions.

A method is described for the determination of the taking of a medication utilizing at least one physiological parameter monitoring platform. In addition, the method also may enable the determination of physiological effects or events resultant from the taking of a medication (or lack thereof) through the use of one or more physiological monitoring platforms.

The present invention relates to a decision support system (DSS), a medical monitoring system (100), and a corresponding method for identifying the need for measurement of cardiac output (CO) based on one or more comparisons (COMP1, COMP2) in a physiological model. More specifically, for identifying when an approximated value of CO cannot be correct due to circulatory compromise and as such that another estimated or measured value of CO is required.

A measurement apparatus includes a wearing portion to be worn by a subject and at least one sensor supported by the wearing portion and configured to acquire biological information of the subject while in contact with a measured part of the subject. The sensor contacts the measured part at a predetermined pressure or less while the wearing portion is worn by the subject.

Provided is an electronic device to monitor a user's biological measurements, where a sensor is configured to acquire a first signal from a user, and a diagnostic processor is configured to pre-process the first signal to generate a second signal, segment the second signal to form signal segments, determine at least one event location for each of the signal segments, match adjacent signal segments for feature alignment, and provide a third signal using results of the feature alignment.

The non-invasive blood glucose level measurement device (1) is provided with a pulse waveform measurement unit (2) having FBG sensors (4) for measuring an acceleration pulse wave of a test subject; and a data-processing unit (3) for calculating the blood glucose level of the test subject at the point in time of measurement of the acceleration pulse wave, from waveform information of the measured acceleration pulse wave, on the basis of a predetermined correlation. The correlation is a calibration curve constructed by carrying out a PLS regression analysis, using the blood glucose level measured by a non-invasive blood glucose method as the objective variable, and a simultaneously-measured acceleration pulse wave as the explanatory variable. A non-invasive blood glucose level measurement device capable of measuring blood glucose level at about the same measurement accuracy as an invasive blood glucose measurement device can be achieved thereby.