A method for producing a nanoscale channel structure disclosed. The method includes depositing and structuring a first sacrificial layer on a substrate, depositing a second sacrificial layer on the substrate and on the first sacrificial layer, depositing an etching masking layer on the second sacrificial layer, partly removing the etching masking layer and the second sacrificial layer, removing the first sacrificial layer and additionally partly removing the second sacrificial layer, depositing a wall layer on the etching masking layer and on the substrate, structuring access openings to the second sacrificial layer, and removing the remaining second sacrificial layer.

A system and method is provided for depositing nanosensors including directing a plasma stream onto a low energy substrate having a surface energy of from 10 mN/m to 43 mN/m to increase the surface energy of the substrate to from 44 mN/m to 80 mN/m, applying an adhesive layer to the plasma discharge treated substrate; and depositing nanosensors on the adhesive coated substrate of step (b) via electrostatic force assisted deposition using a high strength electrostatic field of from 2 kV/cm to 10 kV/cm to form vertically standing nanosensors.

The present invention provides a system and method for building and optimizing biosensors to create a multi-layered bio-sensing system by incorporating two different formats comprised of i) a single wall carbon tubular sensing element and ii) a non-tubular graphene sensing element. This multi-layered system allows for assaying molecules across a large range of molecular weights by sensing molecules in both gas and liquid from a common sample simultaneously. By collecting and analyzing both larger, heavier molecules, including, but not limited to: proteins hormones, nucleic acids, lipids, lipoproteins, etc., with non-tubular graphene sensors and smaller, lighter volatile organic compounds (VOCs) as emitted in gas form from the same sample are assayed with single walled-carbon nanotubules (SWNTs), this invention provides a more complete, holistic understanding of the organism's current state of health.

A small transistor type sensor capable of detecting a specific compound such as oxytocin is provided. The transistor type sensor includes a detection electrode that detects a compound by capturing the compound, and a field effect transistor that has a gate electrode connected to the detection electrode, wherein a surface of the detection electrode is provided with a film of a molecularly imprinted polymer having a space to which the compound is allowed to bond.

A DNA sequencing device and methods of making. The device includes a pair of electrodes having a spacing of no greater than about 2 nm, the electrodes being exposed within a nanopore to measure a DNA strand passing through the nanopore. The device can be made by depositing a conductive layer over a sacrificial channel and then removing the sacrificial channel to form the electrode gap.

In various embodiments of the present disclosure, a molecular electronics sensor array chip comprises: (a) an integrated circuit semiconductor chip; and (b) a plurality of molecular electronic sensor devices disposed thereon, each of said sensor devices comprising: (i) a pair of nanoscale source and drain electrodes separated by a nanogap; (ii) a gate electrode; and (iii) a bridge and/or probe molecule spanning the nanogap and connecting the source and drain electrodes, wherein the molecular electronic sensor devices are organized into an electronically addressable, controllable, and readable array of sensor pixels.

A monolithic, three-dimensional (3D) integrated circuit (IC) device includes a sensing layer, a memory layer, and a processing layer. The sensing layer includes a plurality of carbon nanotube field-effect transistors (CNFETs) that are functionalized with at least 50 functional materials to generate data in response to exposure to a gas. The memory layer stores the data generated by the plurality of CNFETs, and the processing layer identifies one or more components of the gas based on the data generated by the plurality of CNFETs.

A semiconductor device includes a first gate electrode, an insulating part, a source electrode, a drain electrode, and a contact part. The insulating part is on one surface of the first gate electrode. The source electrode is connected to the insulating part. The drain electrode is connected to the insulating part. The contact part is between the source electrode and the drain electrode and on the insulating part. The contact part contains an atomic layered material. The contact part has a second part contactable with a sample. The second surface is opposite to a first surface facing the insulating part. A surface of the insulating part, the surface facing the contact part, has an uneven structure with respect to the first gate electrode.

An electrochemical ion sensor and a method for sensing a presence of at least one ion species in a solution are provided. The electrochemical sensor includes a solid-state electrolyte medium doped with an organometallic material, having an electrochemical affinity with the ion species, and a pair of electrodes electrically contacting the solid-state electrolyte. The electrochemical sensor also includes an electrical circuit configured to drive the pair of electrodes with an AC electrical excitation and to measure at least one parameter related to a complex electrical impedance of the doped solid-state electrolyte medium in response to the AC electrical excitation. The parameter may be an electrical resistance, an inductance or a combination of both, and represents the presence of the ion species in the solution when the solid-state electrolyte medium is exposed to the solution.

A wireless sensor platform design and a single walled carbon nanotube/ionic liquid-based chemidosimeter system can incorporated into a highly sensitive and selective chemical hazard badge that can dosimetrically detect an analyte down to a sub parts-per-million concentration.