A method for quantification of the concentration of one or more cannabinoid compounds in a liquid sample is provided. The method involves contacting the liquid sample with at least one cannabinoid-sensitive visualization reagent, allowing the at least one cannabinoid-sensitive visualization reagent to develop for a defined amount of time; and comparing the resulting color change of the at least one cannabinoid-sensitive visualization reagent to a calibrated quantification reference chart.

Contamination detection systems, kits, and techniques are described for testing surfaces for the presence of hazardous contaminants, while minimizing user exposure to these contaminants. Even trace amounts of contaminants can be detected. A collection kit provides a swab that is simple to use, easy to hold and grip, allows the user to swab large areas of a surface, and keeps the user's hands away from the surface being tested. The kit also provides open and closed fluid transfer mechanism to transfer the collected fluid to a detection device while minimizing user exposure to hazardous contaminants in the collected fluid. Contamination detection kits can rapidly collect and detect hazardous drugs, including trace amounts of antineoplastic agents, in healthcare settings at the site of contamination.

A configurable washing arrangement (176) washes away at least unreacted components (230, 630) of patient samples (224, 624) from a reaction cell (220, 320) with a multiple number of wash actions (206, 210, 606). The configurable washing arrangement is suitable for use with an immunoassay diagnostic system (100) and washes the reaction cell within a predetermined timed sequence (Tww). The number of the wash actions correspond with an assay type of a plurality of assay types (200, 600). The various number of wash actions may be selected without compromising overall process speed. The immunoassay diagnostic system is configured to perform the plurality of the assay types and thereby detect analytes (244, 644) in patient samples (224, 624) by at least combining each of the patient samples with at least one reagent (216, 232, 616) in the reaction cell.

This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

A time-resolved fluorescence immunochromatography test paper card for detecting butralin, which comprises a cover body and a housing body, wherein the cover body is provided with a test hole, a loading hole and a through-hole, an isolating mechanism is arranged in the test hole and the loading hole, the isolating mechanism comprises a first isolating ring and a second isolating ring, the top lateral walls of which are respectively provided with a first lug boss and a second lug boss, one end of the upper surface of the working board is concave towards the inner of the working board to provide a groove, there is a nitrocellulose membrane, a binding pad, a sample pad and a mark zone successively provided between the water absorbing block and the other end of the working board, and the lateral wall at one end of the working board is provided with a bump.

An indicator of a first type and an indicator of a second type are attached to a unit of a chemical component in a sample to form a first multi-indicator complex. The first multi-indicator complex includes the unit of the chemical component, the indicator of the first type, and the indicator of the second type. The indicator of the first type and the indicator of the second type have different discernible characteristics. An image of the sample, including the first multi-indicator complex corresponding to the unit of the chemical component, is captured by an image sensor. Based on a first image of the sample, a count is generated of multi-indicator complexes that include an indicator of the first type and an indicator of the second type, including the first multi-indicator complex. Based on the count, a presence or a level of the chemical component in the sample is identified.

Medical test cards for detecting analytes are provided including a substantially planar body, an analyte detection means, an opening feature, and an optical code. The analyte detection means is enclosed within the planar body and is configured to provide a colorimetric change when a portion of the analyte detection means is contacted with the analyte. The opening feature is configured to provide access to the analyte detection means and the optical code includes information identifying the analyte detection means. Uses of such medical test cards include accessing the analyte detection means enclosed within the planar body by using the opening feature and contacting the analyte detection means with the sample. The optical code is read using an imaging device to identify the analyte detection means and the analyte detection means is imaged following contact with the sample using the imaging device.

An instrument for detecting signal from a biological sample includes a pipettor module configured to hold a plurality of pipettes in respective pipette positions, to hold liquid in one or more pipette tips, and to pipette liquid in and out of the one or more pipette tips. Each of the one or more pipette tips has a pipette tip point. The instrument further includes one or more magnets positioned such that each of the one or more pipette tips is adjacent one of the one or more magnets.

In some embodiments, the present invention is a device, including: a swab including an absorptive component attached to a stem, an extraction chamber configured to receive the swab and position the absorptive component of the swab configured to be in fluid communication with an extraction reagent, a test strip configured to be brought in fluid communication with the extraction reagent following extraction of the analyte from the biological sample, including: a sample receiving portion configured to accept a sample, a site on the strip where the analyte-specific labeled reagent has been incorporated, such reagent configured to bind the analyte from the biological sample, a capture portion configured to receive: the analyte from the biological sample and the analyte-specific labeled reagent so as to result in displaying a positive or negative result at the completion of the assay, and an adsorbent pad attached to the test strip.

A luminometer (400) includes a light detector (630) configured to sense photons (135). The luminometer (400) includes an analog circuit (915a) configured to provide an analog signal (965) based on the photons (135) emitted from assay reactions over a time period and a counter circuit (915b) configured to provide a photon count (970) based on the photons (135) emitted from the assay reactions over the time period. The luminometer (400) includes a luminometer controller (905) configured to, in response to an analog signal value of the analog signal (965) being greater than a predetermined value, determine and report a measurement value of the photons (135) emitted from the assay reactions over the time period based on the analog signal value of the analog signal (965) and a linear function (1010). Optionally, the linear function (1010) is derived from a relationship between the analog signal (965) and the photon count (970).