Systems, methods, and collection devices are disclosed for rapid, local PCR testing. The PCR testing system may be configured for use with a disposable sample collection device that includes a swab configured for collecting a biological sample from a patient; and a sample container configured to receive the swab and separate a bulk quantity of the biological sample from the swab for containment in a bulk collection chamber, which is located with the sample container, wherein the sample container is configured to meter a selected volume of the biological sample into a PCR sample tube, which contains a lyophilized master mix, releasably attachable to the sample container.

Provided herein, in some embodiments, are rapid diagnostic tests to detect one or more target nucleic acid sequences (e.g., a nucleic acid sequence of one or more pathogens). In some embodiments, the pathogens are viral, bacterial, fungal, parasitic, or protozoan pathogens, such as SARS-CoV-2 or an influenza virus. In one embodiment, a rapid test method is provided comprising performing an isothermal nucleic acid amplification-based rapid test, accessing fluorescence data of a reaction tube of the test, and visually detecting, via the fluorescence data, presence or absence of a target pathogen, such as COVID-19 and/or an influenza virus and/or a target nucleic acid.

One embodiment of the invention is directed to a sample processing system for analyzing a biological sample from a patient. The sample processing system comprises: a plurality of analyzers comprising at least one mass spectrometer, wherein each analyzer in the plurality of analyzers is configured to acquire at least one measurement value corresponding to at least one characteristic of the biological sample; at least one data storage component which stores (i) a list of parameters for the plurality of analyzers, and (ii) at least two condition sets, which contain data associated with completing one or more test orders. The condition sets contain data which differ by at least one variable; and a control system operatively coupled to the plurality of analyzers, and the at least one data storage component. The control system is configured to (i) determine which condition set of the at least two condition sets to use based on the determined condition set, (ii) determine which analyzer or analyzers of the plurality of analyzers to use to process each test order based on the determined condition set and one or more parameters from the list of parameters, and (iii) cause the determined analyzer or analyzers to acquire one or more measurement values for the biological sample.

The health support system according to a preferred embodiment includes a sensor that outputs an output signal corresponding to a specific component in urine, a transmitter connected to the sensor, and a user terminal carried by the user. The user terminal includes a storage unit that stores an identifier corresponding to the user, a wireless receiving unit that receives a wireless signal from the transmitter, an output unit that outputs the data to an analysis system that analyzes the health state of the user based on a specific component indicated by the data when the identifier indicated by the wireless signal matches the identifier stored in the storage unit, and an acquisition unit that acquires information corresponding to the results of the analysis of the analysis system.

A system performs one or more magnetic resonance (MR) measurements on at least a portion of a biological life form. Moreover, the system quantitatively simulates an MR response of at least the portion of the biological life form, and compares the one or more MR measurements and the quantitative simulation to obtain a first test result. Next, the system determines one or more additional medical tests to perform. In response, the system accesses the biological sample in storage, and performs the one or more additional medical tests on at least a second portion of the biological sample to obtain one or more additional test results. Furthermore, the system computes a second test result based at least in part on the first test result and the one or more additional test results, where the second test result has an improved accuracy relative to the first test result.

Example implementations relate to a microfluidics sensing system. For example, a microfluidics sensing system may include a portable computing device to execute a microfluidics application, a microfluidic chip coupled to the portable computing device, the microfluidic chip including a microfluidic pumping and sensing region to perform a test on a biologic sample, and a printed circuit board (PCB) on a microfluidic reader to instruct the microfluidic pumping and sensing region to perform the test based on a command received from the microfluidics application.

A urine sample testing apparatus may include a urine qualitative measuring section configured to acquire a measurement result for each of a plurality of urine qualitative measurement items and a urine sediment measuring section configured to acquire a measurement result for each of a plurality of urine sediment measurement items. The apparatus may also include an operation part that can specify a combination of one of the plurality of urine qualitative measurement items and one of the plurality of urine sediment measurement items. An information processing unit may also be included.

Methods and devices to monitor an analyte in body fluid are provided. Embodiments include continuous or discrete acquisition of analyte related data from a transcutaneously positioned in vivo analyte sensor automatically or upon request from a user. The in vivo analyte sensor is coupled to an electronics unit holding a memory with instruction to cause processing circuitry to initiate a predetermined time period that is longer than a predetermined life of the sensor, during the predetermined time period, convert signals from the sensor related to glucose to respective corresponding glucose levels, without relying on any post-manufacture independent analyte measurements from a reference device, and at the expiration of the predetermined time period, disable, deactivate, or cease use of one or more feature.

The claimed invention provides personalized glucose and insulin information to a user in need thereof. Non-invasive body fluid capture techniques utilize saliva to provide body levels of glucose and insulin as well as optional pharmaceutical ingestion coordinated over time. Saliva captured on cellulose strips are analyzed in real time using oxidation and aptamer conjugate hybridization together with traditional analytical chemistry techniques including liquid chromatography/mass spectrometry (LC/MS) and coordinated against time of pharmaceutical administration. By embracing the P4 (Participatory, Personalized, Predictive, and Preventive) health management method the patient can determine glucose and insulin related wellness levels and if a pharmaceutical is having the correct and desired effect for maximum therapeutic benefit.

Systems and methods for monitoring the health status of a subject are provided. In certain embodiments, the method includes: applying a sample provided from a subject to a signal enhancing detector configured to indicate an output that is representative of the sample; processing the output with a device configured to acquire the detector output as input data and process the input data to generate a report; and receiving the report. In certain embodiments, the device is a mobile device. In certain embodiments, the method further includes transmitting the sample-derived data in the device to a remote location where the transmitted data is analyzed; and receiving the results of the analysis. Also provided are systems for use in practicing the methods. Kits for use in monitoring the health status of a subject are also provided.