The present invention provides novel peptides, compositions, and methods for creating quantitative novel compositions, as well as methods for creating quantitative standards to calibrate analytes. These peptides, compositions, and methods enable the creation of standards and calibrators for analyzing analytes and measuring clinical biomarkers (e.g., Tau). Also provided are kits comprising the peptides or compositions described herein, for use in assays (e.g., sandwich immunoassays).

This invention relates to glucose-sensitive albumin-binding diboron conjugates. More particularly the invention provides novel diboron compounds, and in particular diboronate or diboroxole compounds, useful as intermediate compounds for the synthesis of diboron conjugates. The diboron compounds are characterized by formula (I), which is: R1-XR2, and wherein X is a mono- to multiatomic linker and where R.sup.1 and R.sup.2, which may be identical or different, each represents a group of Formula (11a) or (IIb) Also described are diboron conjugates represented by the general Formula (I), which is: R1-XR2, in which either the moeities R1 or R2 or X carry a drug that is covalently attached to the diboron compound.

Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

Systems and method that relate to improving levels, functions, and resistances related to chronic conditions by using lysine-based supplements are described. For example, a method of monitoring an analyte level may include administering a supplement that may include lysine, zinc, and vitamin C to a user. The method may also include monitoring an analyte level in a bio-sample before and after the supplement is administered.

The present invention concerns a method for determining the concentration of a protein in a gastrointestinal (GI) tract sample taken from a human or an animal. The present invention is characterized by the feature that a dilution of the sample in the buffered aqueous extraction medium in a range of 1:100 to 1:10,000 is obtained. The present invention leads to a significant improvement of the technical situation, and provides a simple, sensitive and specific determination tool of proteins in GI tract samples. The determination of proteins, e.g. calprotectin, elastases or hemoglobin, in GI tract samples leads to more accurate and reproducible results.

Systems and methods for a urinalysis home testing kit are provided. In one implementation, a system may include a container configured to contain a urine sample, a dipstick including a plurality of test reagent pads thereon for measuring differing urinary properties, a blot pad, and a colorized surface containing a dipstick placement region and a plurality of colored reference elements greater than a number of the plurality of test reagent pads. The blot pad may be for removing excess urine from the dipstick after being dipped in urine, to thereby enable non-distorted image capture of the plurality of reagent pads by an image sensor. The colorized surface may be for enabling color normalization of the plurality of test reagent pads using the plurality of colored reference elements.

Systems and methods for tracking healing progress of multiple adjacent wounds are provided. In one embodiment, a system may include a processor configured to receive a first image of a plurality of adjacent wounds near a form of colorized surface having colored reference elements, determine colors of the plurality of wounds, correct for local illumination conditions, receive a second image of the plurality of wounds near the form of colorized surface, to determine second colors of the plurality of wounds in the second image, match each of the plurality of wounds in the second image to a wound of the plurality of wounds in the first image, and determine an indicator of the healing progress for each of the plurality of wounds based on changes between the first image and the second image.

Systems and methods for a color board for use in reagent strip testing are disclosed. One implementation may include a color board surface, a first colored reference element printed on the color board surface, and a second colored reference element printed on the color board surface. The color board may also include a test region on the color board surface configured to receive at least one reagent pad. The color board may also include a unique code, and the code may reflect specific chromatic properties associated with each of the first colored reference element and the second color reference element at a time of printing. The unique code may be machine readable to enable a machine to later normalize a comparison color, for determining chromatic properties of the at least one reagent pad.

Systems and methods automatically populate an electronic medical record of a patient with the results of image analysis. A token is generated for a specific patient in need of a medical test. The token is transmitted to a mobile communications device associated with the specific patient. Once a token-based communications session is initiated between the mobile communications device and a remote server, image-related information is transmitted to the remote server from the mobile communications device to perform an analysis of the image-related data. Upon verification that the transmitted image-related information is associated with the specific patient, an electronic medical record of the specific patient is updated to reflect a test result.

A method of updating an electronic medical record based on patient generated image data includes providing a test kit and a verification code to a patient. The patient performs a procedure associated with the test kit, then captures a medical image. The verification code is used to verify that the image was received from the patient. Upon verification, a notification is sent to a healthcare provider for updating an electronic medical record of the patient with data associated with the new image.