An aspiration system includes a plurality of catheters located at least partially within the lumen of an outer sheath. The outer sheath and the catheters are configured to slide relative to each other between a first state in which the distal ends of the catheters are located within the lumen of the outer sheath, and a second state in which the distal end and an end length section of each catheter is extended through the distal end of the outer sheath and outside of the lumen of the outer sheath. The end length section of each catheter is configured to spring or flare outward relative to the first state, when the outer sheath and the plurality of catheters are in the second state. The distal end of the outer sheath may be placed in an inferior vena cava or iliac vein in a transplant kidney patient, adjacent at least one renal vein, with the outer sheath and the plurality of catheters in the first state. Then, the system may be transitioned to the second state to cause the end length sections of the catheters to spring or flare outward adjacent the renal vein. The catheters are connected to a suction source for aspiration through the catheter end length sections.

An aspiration system includes a plurality of catheters located at least partially within the lumen of an outer sheath. The outer sheath and the catheters are configured to slide relative to each other between a first state in which the distal ends of the catheters are located within the lumen of the outer sheath, and a second state in which the distal end and an end length section of each catheter is extended through the distal end of the outer sheath and outside of the lumen of the outer sheath. The end length section of each catheter is configured to spring or flare outward relative to the first state, when the outer sheath and the plurality of catheters are in the second state. The distal end of the outer sheath may be placed in an inferior vena cava or iliac vein in a transplant kidney patient, adjacent at least one renal vein, with the outer sheath and the plurality of catheters in the first state. Then, the system may be transitioned to the second state to cause the end length sections of the catheters to spring or flare outward adjacent the renal vein. The catheters are connected to a suction source for aspiration through the catheter end length sections.

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

An improved valve leak detection system. The improved valve leak detection system comprises a membrane pump defining a flow path arranged to be opened and closed by at least one valve, a measuring device, a comparator, and a signal generator. The measuring device is configured to determine a conductivity value between two points on the flow path of the membrane pump, one point arranged upstream of the at least one valve and the other point arranged downstream of the at least one valve. The measuring device measures the conductivity value when the at least one valve is closed. The comparator is configured to continuously monitor the conductivity value. The signal generator is arranged to provide an output signal when the conductivity value is indicative of a valve leak condition for a set number of measurements within a set period of time.

An improved valve leak detection system. The improved valve leak detection system comprises a membrane pump defining a flow path arranged to be opened and closed by at least one valve, a measuring device, a comparator, and a signal generator. The measuring device is configured to determine a conductivity value between two points on the flow path of the membrane pump, one point arranged upstream of the at least one valve and the other point arranged downstream of the at least one valve. The measuring device measures the conductivity value when the at least one valve is closed. The comparator is configured to continuously monitor the conductivity value. The signal generator is arranged to provide an output signal when the conductivity value is indicative of a valve leak condition for a set number of measurements within a set period of time.

A dialysis fluid system includes a dialysis fluid inlet; a dialysis fluid outlet; a pump positioned and arranged to pump dialysis fluid through the dialysis fluid inlet and the dialysis fluid outlet; and an inductive heater located between the dialysis fluid inlet and the dialysis fluid outlet, the inductive heater including a fluid flowpath positioned and arranged to receive non-heated dialysis fluid from the dialysis fluid inlet and to output heated dialysis fluid to the a dialysis fluid outlet, a conductive heater element located within the fluid flowpath so as to be or act as a secondary coil of a transformer, and a primary coil of the transformer located outside of the fluid flowpath and positioned so as to magnetically induce a current into the conductive heater element, causing the conductive heater element and surrounding fluid to heat.

A dialysis fluid system includes a dialysis fluid inlet; a dialysis fluid outlet; a pump positioned and arranged to pump dialysis fluid through the dialysis fluid inlet and the dialysis fluid outlet; and an inductive heater located between the dialysis fluid inlet and the dialysis fluid outlet, the inductive heater including a fluid flowpath positioned and arranged to receive non-heated dialysis fluid from the dialysis fluid inlet and to output heated dialysis fluid to the a dialysis fluid outlet, a conductive heater element located within the fluid flowpath so as to be or act as a secondary coil of a transformer, and a primary coil of the transformer located outside of the fluid flowpath and positioned so as to magnetically induce a current into the conductive heater element, causing the conductive heater element and surrounding fluid to heat.

Filtration systems and methods using a pump and pressure sensor are provided for improved efficiency in fluid filtration systems. A filtration system includes a pre-filter container joined to a post-filter container by a filter line having a filter. To reduce the time required for filtration a pump and pressure sensor are included in a filter inlet flow path. The pump also is used to provide air management in the system via pre-filtration evacuation of air from at least the filter.

An assembly for an extracorporeal life support system with a suction line that features a venous cannula and a pressure line that features an arterial cannula furthermore includes a pump that is arranged between the suction line and the pressure line. This assembly has a discharge line with a discharge cannula, wherein the discharge cannula is longer than the arterial cannula, and wherein the discharge line is connected to the suction line or the pressure line.