An apparatus includes a shaft having a proximal end and a distal end; a stem extending from the distal end of the shaft and comprising a first cover and a second cover, the first cover and the second cover being configured to inhibit access to fallopian tubes of a patient; and a plurality of temperature sensors disposed on the shaft and on the stem. At least one of the temperature sensors is positioned between the proximal end of the shaft and the distal end of the shaft and at least one of the temperature sensors is positioned on the stem.

An extended forward looking RF coil is shaped similarly to the tip of a pencil, for use in imaging and visualization of anatomy or certain conditions, including cancer. The RF coils are designed using the concept of image RF fields. The coils all include an inner void, which is surrounded by a cone-shaped plastic enclosure. A metallic layer is deposited on a surface of the cone and serves as a metallic layer backing the coils. The metallic layer includes a dielectric region, with altered size and geometry. Several solenoidal coil windings are placed outside the dielectric. The coil windings are denser on the Left (Forward) as compared to the Right (Backwards), in order to concentrate the magnetic field in the Forward direction. The extended forward looking coil is further integrated into an anatomy-specific, imaging array with sideways-looking RF coils, intended for improved imaging along cylindrical sides of the pencil-shaped device.

A system for imaging and examination of a cervix, comprising a control module connectable with a changeable head configured to image the cervix and collect a tissue biopsy, the head selected from a group consisting of a digital colposcope module, a transvaginal optical probe module and an endo-cervical endoscope module. The system may additionally comprise light source(s) to illuminate cervix tissue; sensing device(s) to generate signal(s) from light and/or to acquire image(s) of a portion of a cervix; and processor(s) in communication with the sensing device(s). The system is configured to: (i) analyze the signal(s); (ii) detect the size of the cervix; (iii) determine parameters defining properties of the cervix; (iv) determine and distinguish normal tissue from abnormal tissue within the cervix; (v) determine the location of area(s) of abnormal tissue in the cervix; and (vi) generate a panoramic view of the cervix.

Devices, systems and related methods for direct and in-vivo monitoring and stimulation of the endometrial cavity include a plurality of sensing modalities incorporated on a set of flexible conductive filaments that allows its insertion in an endometrial cavity through the vagina. The flexible set of conductive filaments is in direct contact with the endometrium to maximize recording sensitivity and acquire direct readings, which correspond to the functionality of the endometrium and/or electrically stimulate endometrial peristalsis in a controlled manner. The same electrodes can be used for a controlled stimulation to strengthen weakened muscle tissue before and after medical and surgical interventions on the uterus, to reset to normal contractility. The methods and systems disclosed herein can be used to improve the chances of success for artificial insemination, including in-vitro fertilization, embryo transfer, and intrauterine insemination, diagnostic tests, and may further improve the overall understanding of endometrial functionality.

A method for non-invasively classifying a tumorous modification of a tissue according to different stages of the tumorous modification comprises the steps of: a) receiving raw magnetic resonance imaging (MRI) data that has been recorded by applying at least one diffusion weighted imaging (DWI) sequence using three to nine different b-values to a tissue being suspicious to a tumorous modification without application of a contrast agent; b) extracting at least two quantification scheme parameters from the raw MRI data by using at least one quantification scheme, wherein each of the quantification scheme parameters is related to a microstructural property of the tissue; c) applying a weight to each quantification scheme parameter, wherein the weight is dependent on a kind of the tissue and on the quantification scheme, whereby a set of weighted quantification scheme parameters is obtained; d) determining a scoring value by combining the weighted quantification scheme parameters within the set, wherein each of the weighted quantification scheme parameters is used only once for determining the scoring value; and e) classifying the tumorous modification of the tissue into one of at least two classes according to the scoring value. The method and a corresponding classification device are capable of performing non-invasive tissue characterization without contrast agent administration in a highly accurate manner while supplementary information related to conventional imaging properties and clinical information can further increase the high diagnostic accuracy. They are used in their entirety for classifying the tumorous modification of the tissue.

A non-invasive and accurate vagina evaluation device and uterine evaluation devices are provided that measure the receptivity (uterine implantation capacity) of the mother's body to a fertilized egg implanting itself into the uterus. A first vagina evaluation device includes: a main body stretchable and expandable after insertion into a vagina, followed by air injection thereinto; four electrodes brought into contact with the vagina wall as the main body expands and stretches; and fixation means configured to fix the interval of arrangement of the electrodes. Second and third uterine evaluation device include: a flexible and rod-shaped main body for insertion into a uterine cavity; and four or two impedance electrodes arranged with a predetermined interval therebetween in an insertion direction of the main body and brought into contact with an endometrium of the uterine cavity to measure a uterine endometrial impedance generated between the endometrium and each of the electrodes.

Methods and system are described for multi-modal, multi-parametric, non-invasive, and real-time assessment of cervical tissue through a multi-modal probe device for use within a vaginal canal and an associated imaging system to assess a risk of preterm delivery of an expectant mother. The multi-modal system may include ultrasound (US) imaging, viscoelastic (VE) imaging, and/or photoacoustic (PA) imaging of the cervical issue to determine cervical biomarker information indicative of parameters including, but not limited to, a collagen to water ratio such that a more water dominant ratio is indicative of a risk of preterm delivery.

The disclosure concerns a medical kit arranged with componentry for fluorescein sodium (FNa)-based diagnosis and trichloroacetic acid (TCA)-based treatment of neoplastic tissue, and related methods for utilizing aspects of the medical kit.

A medical monitoring device comprises at least one inspection sensor, configured to detect one or more events, changes or characteristic of tissue, when interfaced with a patient's body, and at least one auxiliary sensor configured to provide data regarding actuation of the device with relation to the anatomy of the patient's body.

A system for the imaging and analysis of human lesions having an illumination component, an imaging sensor, a tunable liquid imaging lens, and driver controlling different focal length settings of the electrically tunable liquid imaging lens. An enclosure houses the tunable liquid imaging lens, the illumination component, and the imaging sensor. The tunable liquid imaging lens has either a bendable lens membrane allowing the focal length to be controlled by fluid pressure, or the tunable liquid imaging lens includes two transparent liquids that are placed between two electrodes to control the focal length. An imaging sensor captures lesion images within a fraction of a second from each other across a range of focus settings to produce a single, sharp, all-focus image.