A pulse application method includes: setting a wavelength of light within a range in which a temperature rise width of collagen fibers in living tissue when the light is applied to the living tissue is larger than a temperature rise width of water containing cells that are contained in the living tissue and that are present around the collagen fibers; and applying a pulse of light with the set wavelength to the living tissue to heat the living tissue.

Dermatological systems and methods for providing a therapeutic laser treatment of tissue having poor chromophore selectivity using a laser source having a grating element to provide laser light having reduced linewidth. In some embodiments, the linewidth is reduced by at least half compared to the linewidth that would be provided in a system without the grating filter element. The linewidth may be reduced in some cases to 500 GHz or less, 300 GHz or less, or 200 Hz or less.

A medical interventional tool has distal and proximal ends. A responsive material is located at the distal end or elsewhere along the interventional tool and is capable of providing a temperature-dependent or pressure-dependent optical response. At least one optical guide is in optical communication with the responsive material to collect an optical signal from the responsive material located at the distal end or other location along the interventional tool. The at least one optical guide further guides the collected optical signal to an optical output at the proximal end of the interventional tool. An optical response analyzer is configured to receive the collected optical signal from the optical output and to process the collected optical signal to derive therefrom a temperature or pressure reading or indication representative of a temperature or pressure at the distal end or other location along the interventional tool.

A method of assessing optical properties of surgical tissue by observing the tissue thermal response to laser irradiation includes exposing the tissue in a surgical region to a short laser pulse for triggering a localized temperature increase, and observing the triggered temperature increase by a thermal sensor. Optical properties of the tissue are then estimated, for determining laser surgery parameters for an eminent procedure, based on the observed temperature increase. In an example configuration, the thermal sensor is a thermal infrared camera, and estimation includes using an Ensemble Kalman Filter (EnKF) for comparing the temperature sensor data with the output of a computational laser-tissue interaction model.

Systems and methods for treating a body region are provided herein. A treatment device for treating a body region is provided, and may include a first applicator and a second applicator. The first and second applicators are held on the body region by a belt. The first applicator may include a first magnetic field generating device and a radiofrequency electrode. The second applicator may include a second magnetic field generating device. The first and second magnetic field generating devices may each generate a time-vary magnetic field with a plurality of sequential magnetic impulses to cause muscle contraction in the body region. The radiofrequency electrode may provide radiofrequency waves causing heating of tissue within the body region. The treatment device may further include an energy storage device and a switching device. The switching device my discharge energy from the energy storage device to the first or the second magnetic field generating device to generate the time-vary magnetic field.

An energy delivery system comprises a transmission member and an antenna at a distal end of the transmission member. The antenna includes a first conductive arm, an insulator extending around the first conductive arm, and a second conductive arm. The second conductive arm includes a coil. The system also comprises a barrier layer radially spaced from the insulator and surrounding the transmission member and antenna. The barrier layer extends from a proximal portion of the transmission member to a distal portion of the antenna. The system also comprises a jacket surrounding the barrier layer and forming a fluid channel for flow of a cooling fluid.

The present disclosure is directed to systems, device and methods for cancer ablation treatment of human and animal subjects through the application of a combination of electromagnetic sources, in particular, microwave and radio frequency radiation that are focused on a tumor harboring magnetic or other metallic nanoparticles to result in synergetic heating effect whereby the tumor is heated to ablative temperature due to the strong absorption of the nanoparticles while the surrounding healthy tissue is hardly affected.

A method of cutting a bone (2) comprises the steps of: preparing the bone (2) in order to be accessible to an osteotomic instrument; predefining an osteotomic geometry on the bone (2); and applying the osteotomic instrument to the bone (2) thereby cutting the bone (2) along the osteotomic geometry and generating a cut surface (21) to the bone (2). The method further comprises delivering a laser beam to the cut surface (21) of the bone (2) such that the cut surface (21) of the bone (2) is ablated. The method according to the invention allows to improve healing of a bone at its cut surface after being cut by the osteotomic instrument.

According to an aspect, there is provided a handheld device (2) for applying energy pulses to skin (17) of a subject to perform a treatment operation as the handheld device is moved across the skin, the handheld device comprising: an aperture (6) that is to be placed adjacent to the skin; at least one energy source (8) for generating an energy pulse and for providing the energy pulse through the aperture to perform the treatment operation on 5 skin adjacent the aperture, wherein the at least one energy source has a minimum pulse repetition period following the generation of an energy pulse before a subsequent energy pulse can be generated; a first skin property sensor (14) for measuring a skin property and for outputting a first measurement signal representing measurements of the skin property at a first sensing position (24), wherein the skin property is a property that changes in response to the application of an energy pulse to the skin, and wherein the first sensing position is in front of the aperture relative to an intended motion direction of the handheld device over the skin; a second skin property sensor (16) for measuring the skin property and for outputting a second measurement signal representing measurements of the skin property at a second sensing position (26), wherein the second sensing position is behind the aperture relative to the intended motion direction; a memory unit (56); and a control unit (10) that is coupled to the at least one energy source to control the generation of energy pulses by the at least one energy source, and coupled to the first skin property sensor and the second skin property sensor to obtain the first measurement signal and the second measurement signal, wherein the control unit is configured to store a profile of at least the first measurement signal in the memory unit; wherein the control unit is further configured to, when the handheld device is moving in the intended motion direction over the skin: analyse the profile of the first measurement signal to determine if the first skin property sensor is passing over a previously treated area of skin; on detecting that the first skin property sensor is not passing over a previously treated area of skin, control the at least one energy source to generate an energy pulse if, or once, the minimum pulse repetition period following the generation of a previous energy pulse has expired; on detecting that the first skin property sensor is passing over a previously treated area of skin, performing the consecutive operations of: preventing the generation of an energy pulse, even if the minimum pulse repet

Devices, systems, and methods for degassing fluid prior to applying fluid to a treatment site during ablation therapy are provided. In one embodiment, an ablation system can include an elongate body, an ablation element, a heating assembly, and a fluid source. Fluid in the fluid source can be at least partially degassed prior to being provided as part of the system, or, in some embodiments, a degassing apparatus can be provided that can be configured to degas fluid within the system prior to applying the fluid to the treatment site. The degassing apparatus can include one or more gas-permeable and fluid-impermeable tubes disposed therein, which can allow gas to be removed from fluid passing through the apparatus. Other exemplary devices, systems, and methods are also provided.