The present invention provides for the treatment, prevention, and/or reduction of a risk of a disease, disorder, or condition in which aldehyde toxicity is implicated in the pathogenesis, including ocular disorders, skin disorders, conditions associated with injurious effects from blister agents, and autoimmune, inflammatory, neurological and cardiovascular diseases by the use of a primary amine to scavenge toxic aldehydes, such as MDA and HNE.

The present invention relates generally to methods of use and compositions useful for moisturizing skin and/or lightening or whitening skin. The composition includes a combination of Angelica acutiloba root extract and a Salicornia herbacea extract.

Provided herein are compounds and pharmaceutical compositions thereof for treating a birthmark in a subject in need thereof, wherein the compound is according to any one of formula (I), (II), (III), (IV), and (V). wherein, X.sup.1, X.sup.2, X.sup.3, R.sup.1, R.sup.2, R.sup.2a, R.sup.13, R.sup.13a, R.sup.23, R.sup.23a, R.sup.23b, R.sup.33, R.sup.33a, R.sup.33b, R.sup.43, R.sup.43a, R.sup.51, R.sup.53, R.sup.53a, R.sup.53b, bond “a”, and subscript n are described herein.

New cosmetic compositions and their use, in particular, as a shampoo or a cleanser. The compositions are in powder form substantially free of water. The compositions are composed of constituents and ingredients that are natural or of natural origin, non-allergenic, healthy, and free of preservatives. Also, a device including the novel compositions.

The present invention is directed to a personal composition comprising a) a strobilurin; b) salicylic acid wherein the ratio of a:b is from about 1:1 to about 100:1; wherein there is a synergistic anti-inflammatory/cellular stress activity.

The invention relates to an aluminum salt-free, antiperspirant, deodorizing, cosmetic and/or dermatological composition comprising at least one antiperspirant active ingredient, wherein the antiperspirant active ingredient is selected from the group of ionic liquids.

The present invention provides improved anti-aging skin cream formulations. The anti-aging cream formulations contain tretinoin, niacinamide, hyaluronic acid, collagen, red wine extract, α-tocopheryl acetate, Butyrospermum parkii (shea butter) extract, and suspendisse cream. The present invention also provides kits containing the formulations, methods of making the formulations as well as methods of using these formulations to visibly reduce signs of aging.

The invention relates to an anhydrous cosmetic or dermatological formulation comprising a viscose lipid-containing preparation and propellant gas consisting essentially of one or more substances selected from hydrofluorocarbons, n-butane, isobutane and propane. The formulation permits application to the skin by spraying of an otherwise nonsprayable preparation. The formulation is free from readily volatile solvents, surfactants, and preferably free from silicones.

The present invention relates to a low-skin irritating deodorant composition. The composition comprises an effective amount of an active ingredient comprising hexamine, derivatives thereof, or a combination thereof for reducing, inhibiting or suppressing development of malodour from a body part; a buffer system for substantially neutralising topical acidity of the body part; and an anti-irritating agent in an effective amount, wherein the anti-irritating agent comprises one or more botanically derived compounds selected from a group consisting of flavonoids, alkaloids, iridoids, terpenes, phenols, or a combination thereof.

The present invention provides compounds as PPAR agonists and their application, involving a new class of peroxisome proliferator-activated receptor (PPAR) gamma receptor agonist, which can inhibit the production of mitochondrial reactive oxygen species, and most of which can readily cross the blood-brain barrier. The present invention also includes pharmaceutical uses of the compounds.